ID   A0YZ02_LYNSP            Unreviewed;       737 AA.
AC   A0YZ02;
DT   23-JAN-2007, integrated into UniProtKB/TrEMBL.
DT   23-JAN-2007, sequence version 1.
DT   27-MAR-2024, entry version 67.
DE   RecName: Full=Diguanylate cyclase with PAS/PAC and Chase2 sensors {ECO:0008006|Google:ProtNLM};
GN   ORFNames=L8106_18616 {ECO:0000313|EMBL:EAW33728.1};
OS   Lyngbya sp. (strain PCC 8106) (Lyngbya aestuarii (strain CCY9616)).
OC   Bacteria; Cyanobacteriota; Cyanophyceae; Oscillatoriophycideae;
OC   Oscillatoriales; Oscillatoriaceae; Lyngbya.
OX   NCBI_TaxID=313612 {ECO:0000313|EMBL:EAW33728.1, ECO:0000313|Proteomes:UP000000737};
RN   [1] {ECO:0000313|EMBL:EAW33728.1, ECO:0000313|Proteomes:UP000000737}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PCC8106 {ECO:0000313|Proteomes:UP000000737};
RA   Stal L., Ferriera S., Johnson J., Kravitz S., Halpern A., Remington K.,
RA   Beeson K., Tran B., Rogers Y.-H., Friedman R., Venter J.C.;
RL   Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EAW33728.1}.
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DR   EMBL; AAVU01000063; EAW33728.1; -; Genomic_DNA.
DR   RefSeq; WP_009787690.1; NZ_AAVU01000063.1.
DR   AlphaFoldDB; A0YZ02; -.
DR   eggNOG; COG2199; Bacteria.
DR   eggNOG; COG4252; Bacteria.
DR   Proteomes; UP000000737; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd01949; GGDEF; 1.
DR   CDD; cd00130; PAS; 1.
DR   Gene3D; 3.30.70.270; -; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 1.
DR   InterPro; IPR007890; CHASE2.
DR   InterPro; IPR000160; GGDEF_dom.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR000700; PAS-assoc_C.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR013656; PAS_4.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   NCBIfam; TIGR00254; GGDEF; 1.
DR   NCBIfam; TIGR00229; sensory_box; 1.
DR   PANTHER; PTHR46663; DIGUANYLATE CYCLASE DGCT-RELATED; 1.
DR   PANTHER; PTHR46663:SF4; TWO-COMPONENT RESPONSE REGULATOR; 1.
DR   Pfam; PF05226; CHASE2; 1.
DR   Pfam; PF00990; GGDEF; 1.
DR   Pfam; PF08448; PAS_4; 1.
DR   SMART; SM01080; CHASE2; 1.
DR   SMART; SM00267; GGDEF; 1.
DR   SMART; SM00091; PAS; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR   PROSITE; PS50887; GGDEF; 1.
DR   PROSITE; PS50113; PAC; 1.
DR   PROSITE; PS50112; PAS; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000737};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        370..392
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          422..494
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   DOMAIN          495..546
FT                   /note="PAC"
FT                   /evidence="ECO:0000259|PROSITE:PS50113"
FT   DOMAIN          592..725
FT                   /note="GGDEF"
FT                   /evidence="ECO:0000259|PROSITE:PS50887"
FT   COILED          537..564
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   737 AA;  82726 MW;  DD98090A2882FD6F CRC64;
     MLWILRTRVG KFQKYKQKLA SLTGWFSQNR RVILTSSSIA GIVIALRALG LLQPLEWSVL
     DLFFRWRPLE PIDERILIVG IDESDLQAYG FPIPDNKLAQ LLQQINAAEP QAIGLDLYRD
     LPTEPGYAEL VKAFQTIPNI VGIETFESGN GAAVNPPPIL AQKDQVGFNN FMTDTDGVVR
     RGLLHVWFPD DVIIQSFPLK LATIYLENQG VSLPSLAPAS DFPIGEGNII RFRKNDGAYV
     RADAGGYQFL ANLRGPLGRF RQVSMTEVLE GRVSSELIRD RIVLIGPTAP SVKDTHFTSY
     SGGLFQSREK MYGVELMANF VSQILSTALD NRTQIQVWSD PVEWLWILGW SWVGASLCWK
     LRAPYRSTTL VLLLSVGLSG GAYLIFCYGW WIPVVPPLIT LLASAAVVVG YLAHLQGEFK
     RSTDFLSSVI NTIPDPIYVK NKNHHKIVIN QAYCRLVGYP MQTLISKSDY ELFPQQEADI
     VWKQDELAFY LAGEQENEEK LTDAQGITRF IATKRSIHRD AAGNIFLVGV IRDITERKRL
     EEELKRIAAE LEHYNAQLKV HAEQDPLTGL ANRKVFYERL AQSLEWATNN NKLVALFYLD
     LNDFKIINDT MGHHIGDLLL KTVAQRLNDC LRSSDTVARL GGDEFTIILP GIPRKADVAK
     VAEKILQTIN QETHLEGHVV SVTTSIGISV YPLDAHDLNL LTQKADDAMY QAKRSGKNRY
     KFATSSPEFD VQPSPED
//