ID A0Z266_9GAMM Unreviewed; 535 AA.
AC A0Z266;
DT 23-JAN-2007, integrated into UniProtKB/TrEMBL.
DT 23-JAN-2007, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE SubName: Full=Predicted esterase of the alpha-beta hydrolase superfamily protein {ECO:0000313|EMBL:EAW42040.1};
GN ORFNames=MGP2080_11583 {ECO:0000313|EMBL:EAW42040.1};
OS marine gamma proteobacterium HTCC2080.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Cellvibrionales; Halieaceae.
OX NCBI_TaxID=247639 {ECO:0000313|EMBL:EAW42040.1, ECO:0000313|Proteomes:UP000004719};
RN [1] {ECO:0000313|EMBL:EAW42040.1, ECO:0000313|Proteomes:UP000004719}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HTCC2080 {ECO:0000313|EMBL:EAW42040.1,
RC ECO:0000313|Proteomes:UP000004719};
RX PubMed=20472793; DOI=10.1128/jb.00511-10;
RA Thrash J.C., Cho J.C., Ferriera S., Johnson J., Vergin K.L.,
RA Giovannoni S.J.;
RT "Genome sequences of strains HTCC2148 and HTCC2080, belonging to the
RT OM60/NOR5 clade of the Gammaproteobacteria.";
RL J. Bacteriol. 192:3842-3843(2010).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAW42040.1}.
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DR EMBL; AAVV01000002; EAW42040.1; -; Genomic_DNA.
DR AlphaFoldDB; A0Z266; -.
DR eggNOG; COG1752; Bacteria.
DR Proteomes; UP000004719; Unassembled WGS sequence.
DR GO; GO:0004806; F:triglyceride lipase activity; IEA:InterPro.
DR GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-UniRule.
DR CDD; cd07206; Pat_TGL3-4-5_SDP1; 1.
DR Gene3D; 3.40.1090.10; Cytosolic phospholipase A2 catalytic domain; 2.
DR InterPro; IPR016035; Acyl_Trfase/lysoPLipase.
DR InterPro; IPR002641; PNPLA_dom.
DR InterPro; IPR021771; Triacylglycerol_lipase_N.
DR PANTHER; PTHR14226; NEUROPATHY TARGET ESTERASE/SWISS CHEESE D.MELANOGASTER; 1.
DR PANTHER; PTHR14226:SF10; TRIACYLGLYCEROL LIPASE 4-RELATED; 1.
DR Pfam; PF11815; DUF3336; 1.
DR Pfam; PF01734; Patatin; 1.
DR SUPFAM; SSF52151; FabD/lysophospholipase-like; 1.
DR PROSITE; PS51635; PNPLA; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:EAW42040.1};
KW Lipid degradation {ECO:0000256|ARBA:ARBA00022963};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Reference proteome {ECO:0000313|Proteomes:UP000004719}.
FT DOMAIN 134..321
FT /note="PNPLA"
FT /evidence="ECO:0000259|PROSITE:PS51635"
FT REGION 469..535
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 535 AA; 59223 MW; 1E117F3818316750 CRC64;
MANSENYADW LGAARDHDDL TGMTDWRHIE HTDLYDYAQI RLRLDRLRNL RARSDHQGLL
YALNEGIHGN MGGMGKGVLY RMAKAGTKRL IEDYIDEIDA SLKLLAELDD GIIPAQQKMD
FFYRANICFG RSALMLSGGG VLGFLHLGVV NVLLEQGLLP RVISGSSAGA LVAGVLACHT
DDEVADLEEL AILQNGAKED TGFLRKLLTG GPSISLDDLE QLVERLIPNS TFEEAYAKTG
RQVSITIAPA EPHQRSRLLN AVTSPNVYIR SAVMASCAVP GVFPAVMLMA RNVHGEPQPY
LPGRRWIDGS VADDLPAKRL SRLFGTNHHI VSMVNPIATA FISKDEDRGG LSKAAGALGV
GVGREFLNFY RGLAQKRGDK WPRFNMMLHG LHALMDQEYT GDINIMPSFR LANPLRLLSH
LNEEELIRLT HHGAHACYEK VEAIRRCTQI SRTLEDILYR YEYGDLRPDP AAVRKPRSSR
RRPAPTLAQR ERLSGRSDST RVPMKPRSGR AGSGKSAETS KVAQKPVRKA VRVTH
//
