ID A0Z4C2_9GAMM Unreviewed; 805 AA.
AC A0Z4C2;
DT 23-JAN-2007, integrated into UniProtKB/TrEMBL.
DT 23-JAN-2007, sequence version 1.
DT 27-MAR-2024, entry version 63.
DE SubName: Full=Aminomethyl transferase family protein {ECO:0000313|EMBL:EAW41159.1};
GN ORFNames=MGP2080_09938 {ECO:0000313|EMBL:EAW41159.1};
OS marine gamma proteobacterium HTCC2080.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Cellvibrionales; Halieaceae.
OX NCBI_TaxID=247639 {ECO:0000313|EMBL:EAW41159.1, ECO:0000313|Proteomes:UP000004719};
RN [1] {ECO:0000313|EMBL:EAW41159.1, ECO:0000313|Proteomes:UP000004719}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HTCC2080 {ECO:0000313|EMBL:EAW41159.1,
RC ECO:0000313|Proteomes:UP000004719};
RX PubMed=20472793; DOI=10.1128/jb.00511-10;
RA Thrash J.C., Cho J.C., Ferriera S., Johnson J., Vergin K.L.,
RA Giovannoni S.J.;
RT "Genome sequences of strains HTCC2148 and HTCC2080, belonging to the
RT OM60/NOR5 clade of the Gammaproteobacteria.";
RL J. Bacteriol. 192:3842-3843(2010).
CC -!- SIMILARITY: Belongs to the GcvT family.
CC {ECO:0000256|ARBA:ARBA00008609}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAW41159.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AAVV01000005; EAW41159.1; -; Genomic_DNA.
DR AlphaFoldDB; A0Z4C2; -.
DR eggNOG; COG0404; Bacteria.
DR eggNOG; COG0665; Bacteria.
DR OrthoDB; 5287468at2; -.
DR Proteomes; UP000004719; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR Gene3D; 2.40.30.110; Aminomethyltransferase beta-barrel domains; 1.
DR Gene3D; 3.30.70.1400; Aminomethyltransferase beta-barrel domains; 1.
DR Gene3D; 3.30.9.10; D-Amino Acid Oxidase, subunit A, domain 2; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR006076; FAD-dep_OxRdtase.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR032503; FAO_M.
DR InterPro; IPR028896; GCST/YgfZ/DmdA.
DR InterPro; IPR013977; GCV_T_C.
DR InterPro; IPR006222; GCV_T_N.
DR InterPro; IPR029043; GcvT/YgfZ_C.
DR InterPro; IPR027266; TrmE/GcvT_dom1.
DR PANTHER; PTHR43757; AMINOMETHYLTRANSFERASE; 1.
DR PANTHER; PTHR43757:SF2; AMINOMETHYLTRANSFERASE, MITOCHONDRIAL; 1.
DR Pfam; PF01266; DAO; 1.
DR Pfam; PF16350; FAO_M; 1.
DR Pfam; PF01571; GCV_T; 1.
DR Pfam; PF08669; GCV_T_C; 1.
DR SUPFAM; SSF101790; Aminomethyltransferase beta-barrel domain; 1.
DR SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF103025; Folate-binding domain; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000004719};
KW Transferase {ECO:0000313|EMBL:EAW41159.1}.
FT DOMAIN 6..367
FT /note="FAD dependent oxidoreductase"
FT /evidence="ECO:0000259|Pfam:PF01266"
FT DOMAIN 371..424
FT /note="FAD dependent oxidoreductase central"
FT /evidence="ECO:0000259|Pfam:PF16350"
FT DOMAIN 426..695
FT /note="Aminomethyltransferase folate-binding"
FT /evidence="ECO:0000259|Pfam:PF01571"
FT DOMAIN 719..797
FT /note="Glycine cleavage T-protein C-terminal barrel"
FT /evidence="ECO:0000259|Pfam:PF08669"
SQ SEQUENCE 805 AA; 88778 MW; F8D7DFBD7A5EEFE3 CRC64;
METQAKVVIV GGGIMGVALA YHLAEEGETD VLLIEKGELT SGSTWHAAGQ CPSLVSNYNL
AKIHDYGNRL YPTLEEKTGQ YVSWHASGGI RVARQQADLD WFHYMKGIAD NVGFHMEIIS
PAKIKEINPF YDIDGVLAGA WTLDDGHADP SGLTNAMARG ATNLGVRIVR HNRVLDINAL
PSGDWEIDTE KGKVTAQIIV NAAGSFARQI AQMVGADLPI ANMEHHYIVT GAIQDFVDRD
EEFPVMRDPY ASAYIRQEQK SGLIGIYESS GITEAWGPSG LPPWSSDSEL FPDDLDRIMP
WLERAMHCMP NMLDAGIKRV VNGAIPHSPD GPPLLGPVAG IPNFWLCCGS SFGIAQGAGC
GKYLAQWMVY GDSEINMTGF DPRRFGVFAD RDFMRAKGFQ DYGLTYATPL PGEEFEAARE
CRLSPLYGKL KSKGAIHTQT FGWERPKWFS INGREEDHSY RRNATFDVVR EECLAVRERV
GIIDLTGFAK YDICGADAES FLNRVLANRM PKRDGGIALA HFLSRNGRIL GEATVTRVTS
EHFYLLSAAS AEMRDLDHLT QQVESGEQVT IRNTTDERGV LALVGPKSRD VLAKLTDAPL
DNENFRWRSS QDIEISGMKV RALRINYVGE LGWELHPKME DLSALYDAVW GAGQDQGMVD
FGLYALNSLR MEKAYRGWGT ELTNEVTLLE ADMARFFSRT KADFVGKFAT EEKADNTLKL
VYFEVNAKDS DVRGGEPIFI DDACIGVTTS GGYGYAVEKS LGFGYVSPEH ATPGSAFQVG
LLDARYDARV LEDPAYDATN NRLAS
//
