ID A0Z9S8_NODSP Unreviewed; 1020 AA.
AC A0Z9S8;
DT 23-JAN-2007, integrated into UniProtKB/TrEMBL.
DT 23-JAN-2007, sequence version 1.
DT 27-MAR-2024, entry version 68.
DE SubName: Full=Polyketide synthase {ECO:0000313|EMBL:AHJ29028.1};
GN ORFNames=NSP_27000 {ECO:0000313|EMBL:AHJ29028.1};
OS Nodularia spumigena CCY9414.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales; Aphanizomenonaceae;
OC Nodularia.
OX NCBI_TaxID=313624 {ECO:0000313|EMBL:AHJ29028.1, ECO:0000313|Proteomes:UP000019325};
RN [1] {ECO:0000313|EMBL:AHJ29028.1, ECO:0000313|Proteomes:UP000019325}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCY9414 {ECO:0000313|EMBL:AHJ29028.1};
RX PubMed=23555932;
RA Voss B., Bolhuis H., Fewer D.P., Kopf M., Moke F., Haas F., El-Shehawy R.,
RA Hayes P., Bergman B., Sivonen K., Dittmann E., Scanlan D.J., Hagemann M.,
RA Stal L.J., Hess W.R.;
RT "Insights into the physiology and ecology of the brackish-water-adapted
RT Cyanobacterium Nodularia spumigena CCY9414 based on a genome-transcriptome
RT analysis.";
RL PLoS ONE 8:E60224-E60224(2013).
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DR EMBL; CP007203; AHJ29028.1; -; Genomic_DNA.
DR RefSeq; WP_006194157.1; NZ_CP007203.1.
DR AlphaFoldDB; A0Z9S8; -.
DR STRING; 313624.NSP_27000; -.
DR PATRIC; fig|313624.11.peg.2720; -.
DR eggNOG; COG2220; Bacteria.
DR eggNOG; COG3320; Bacteria.
DR HOGENOM; CLU_296104_0_0_3; -.
DR Proteomes; UP000019325; Chromosome.
DR CDD; cd05235; SDR_e1; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR Gene3D; 1.10.10.1830; Non-ribosomal peptide synthase, adenylation domain; 1.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR041141; CmlA_N.
DR InterPro; IPR013120; Far_NAD-bd.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR InterPro; IPR010080; Thioester_reductase-like_dom.
DR InterPro; IPR041464; TubC_N.
DR InterPro; IPR044894; TubC_N_sf.
DR NCBIfam; TIGR01746; Thioester-redct; 1.
DR PANTHER; PTHR44845:SF6; BETA-ALANINE-ACTIVATING ENZYME; 1.
DR PANTHER; PTHR44845; CARRIER DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF18456; CmlA_N; 1.
DR Pfam; PF13483; Lactamase_B_3; 1.
DR Pfam; PF07993; NAD_binding_4; 1.
DR Pfam; PF18563; TubC_N; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450}.
FT DOMAIN 7..238
FT /note="Diiron non-heme beta-hydroxylase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF18456"
FT DOMAIN 559..613
FT /note="TubC N-terminal docking"
FT /evidence="ECO:0000259|Pfam:PF18563"
FT DOMAIN 651..887
FT /note="Thioester reductase (TE)"
FT /evidence="ECO:0000259|Pfam:PF07993"
SQ SEQUENCE 1020 AA; 115344 MW; 92BAA11DED4AB9C4 CRC64;
MINQLIYLKP NVIVEPLFNQ WYAWSYLISP ATAAMYIAHS HLPIMQSFVA APQVHQDALK
NPAMIGGPFI NYDSSRVEDI QILLETTQKQ QAHLLELAQA IQDLEKILAE HTQGYSLEPL
YEKIPQALRG YVELVQDSNN YPSIRFIEGL LYRSPYYNPA NQSVNLYLGD GDKRAFVLST
PRLPDEQSIH LKMAFSDRAL DQLFQMRHTP QPYEDIRDTL KIKPQQETLF ADFFTTTPPK
QEPDYRGEAV RVRYFGHACV LIQTESISIL CDPIISYPDD SGDNRYTYQH LPPVIDYVLI
THNHQDHIML ETLLQLRHKI QTVVVPKSNK GTLIDPSLKL MLQQIGFKNV REIDELEVIH
LTDGYITGLP FLGEHGDLNI ATKAAYLINL KGRSILCAAD SNNIDPQLYS HLQQIFGDID
VLFIGMECGG APYTWAYGAL LTNQVPRKIA QTRRLDGSDS SRAIALVQQL HPQQVYIYAM
GQEPWLTFIT SIIYTAESKA IIESNQLIAY CHSQEILSKR LFGCEEIFLI PNPKTSSIIG
NIKTHTLLQP EVWGEVSSIQ SFLFELQRLD IRIWLEDTDS IPKLRCNAPK GVLKPTLKAQ
LQERKSEIIE FLQNSGKTKV EIDWQQETTL DSTIIPPSSS SLSPAASSLL LTGATGFIGA
FLLQELLNKT TASIYCLIRA ENIETAKQRI VKTLQNYQIW DNSYSERIIP IVGDLAKPKL
GLSALEFANL ANQIDIIYHN GAKVNHTEPY NRLKSANVLG TQEIFRLASQ SKLKPVHLIS
STSIFAANNH SNLQITEDDN LDKYGIPIGG YAQSKWAAEK LAITAINRGI PVKIYRLGAV
SGDSKTGAFN QDDFLYKLLL GYVQLGSIPD TAMPLEILPV DYVCSAIIEL SKIASNHQIF
HIIQPKPVSS EIIFEQLKKI GFKIEKISYQ QWRNKILEIA QNSPEHILYP LIPLLPKQRT
THESQPNTKL QIDNRKTQNI LNQLITPPTI NENLIQTYLS HLIQQNLIKK PPSNLREPLR
//
