ID A1B122_PARDP Unreviewed; 551 AA.
AC A1B122;
DT 23-JAN-2007, integrated into UniProtKB/TrEMBL.
DT 23-JAN-2007, sequence version 1.
DT 27-MAR-2024, entry version 111.
DE SubName: Full=AMP-dependent synthetase and ligase {ECO:0000313|EMBL:ABL69216.1};
GN OrderedLocusNames=Pden_1108 {ECO:0000313|EMBL:ABL69216.1}, Pden_4590
GN {ECO:0000313|EMBL:ABL72653.1};
OS Paracoccus denitrificans (strain Pd 1222).
OG Plasmid 1 {ECO:0000313|EMBL:ABL72653.1}, and
OG Plasmid pPD1222 {ECO:0000313|Proteomes:UP000000361}.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Paracoccaceae; Paracoccus.
OX NCBI_TaxID=318586 {ECO:0000313|EMBL:ABL69216.1, ECO:0000313|Proteomes:UP000000361};
RN [1] {ECO:0000313|Proteomes:UP000000361}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Pd 1222 {ECO:0000313|Proteomes:UP000000361};
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA Munk A.C., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J.,
RA Larimer F., Land M., Hauser L., Kyrpides N., Lykidis A., Spiro S.,
RA Richardson D.J., Moir J.W.B., Ferguson S.J., van Spanning R.J.M.,
RA Richardson P.;
RT "Complete sequence of chromosome 1 of Paracoccus denitrificans PD1222.";
RL Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ABL69216.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PD1222 {ECO:0000313|EMBL:ABL69216.1};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA Munk A.C., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J.,
RA Larimer F., Land M., Hauser L., Kyrpides N., Lykidis A., Spiro S.,
RA Richardson D.J., Moir J.W.B., Ferguson S.J., van Spanning R.J.M.,
RA Richardson P.;
RT "Complete sequence of Chromosome 1 of Paracoccus denitrificans PD1222.";
RL Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Proteomes:UP000000361}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Pd 1222 {ECO:0000313|Proteomes:UP000000361};
RC PLASMID=pPD1222 {ECO:0000313|Proteomes:UP000000361};
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA Munk A.C., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J.,
RA Larimer F., Land M., Hauser L., Kyrpides N., Lykidis A., Spiro S.,
RA Richardson D.J., Moir J.W.B., Ferguson S.J., van Spanning R.J.M.,
RA Richardson P.;
RT "Complete sequence of plasmid 1 of Paracoccus denitrificans PD1222.";
RL Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:ABL72653.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PD1222 {ECO:0000313|EMBL:ABL72653.1};
RC PLASMID=1 {ECO:0000313|EMBL:ABL72653.1};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA Munk A.C., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J.,
RA Larimer F., Land M., Hauser L., Kyrpides N., Lykidis A., Spiro S.,
RA Richardson D.J., Moir J.W.B., Ferguson S.J., van Spanning R.J.M.,
RA Richardson P.;
RT "Complete sequence of Plasmid 1 of Paracoccus denitrificans PD1222.";
RL Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the ATP-dependent AMP-binding enzyme family.
CC {ECO:0000256|ARBA:ARBA00006432}.
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DR EMBL; CP000489; ABL69216.1; -; Genomic_DNA.
DR EMBL; CP000491; ABL72653.1; -; Genomic_DNA.
DR RefSeq; WP_011747436.1; NC_008688.1.
DR AlphaFoldDB; A1B122; -.
DR STRING; 318586.Pden_1108; -.
DR EnsemblBacteria; ABL69216; ABL69216; Pden_1108.
DR EnsemblBacteria; ABL72653; ABL72653; Pden_4590.
DR GeneID; 75503958; -.
DR KEGG; pde:Pden_1108; -.
DR KEGG; pde:Pden_4590; -.
DR eggNOG; COG0318; Bacteria.
DR HOGENOM; CLU_000022_59_5_5; -.
DR OrthoDB; 9803968at2; -.
DR Proteomes; UP000000361; Chromosome 1.
DR Proteomes; UP000000361; Plasmid pPD1222.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR CDD; cd12118; ttLC_FACS_AEE21_like; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR43859; ACYL-ACTIVATING ENZYME; 1.
DR PANTHER; PTHR43859:SF4; BUTANOATE--COA LIGASE AAE1; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 3: Inferred from homology;
KW Ligase {ECO:0000313|EMBL:ABL69216.1};
KW Plasmid {ECO:0000313|EMBL:ABL72653.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000000361}.
FT DOMAIN 25..409
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 459..533
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 551 AA; 59358 MW; 17030B7E6AB64365 CRC64;
MTEYDEGLER AAANHQPMTP ISYLRRTARI HPDHPAVIHG RQRHGYARLW ADCCRLASAL
LGRGIGRGDT VSVLLSNTPP MIHAHFGVPM AGGAVLHSIN TRSDPATVAF QLDHAESRVL
IVDREFSAMA AEALALAGVR PLVVDFDDAE YPDDAPHPKG EPIGSLDYEQ LLAEGDPDFA
ATPPGDEWDA ISLNYTSGTT GNPKGVVYHH RGAALMALNN VIHAGMGRHP VYLWTLPMFH
CNGWCFPWTV PVQAGTQVCL RWVRAGAIFD AIADHGVTHL CGAPIVMSTL LNAAADRKRG
FPQQVTFNTA AAPPPETVLQ AMAKAGFGVT HLYGLTETYG PAVVNEWNPG WDGLPPSGQA
ARKARQGVRY LSLDELAVMD PETLQPVPAD GRTLGEVMFR GNVVMKGYLK NPEATAAAFA
GGWFHSGDLA VMHPDGYVQL KDRSKDIIIS GGENISSIEV EEQLYRHPAV ALCAVVAMPS
EKWGETPCAF VELREGGEET EPGLIAHCRA GLAGYKCPSR VVFGPLPKTS TGKIQKFALR
ARAAELARAM T
//
