ID A1C8H6_ASPCL Unreviewed; 413 AA.
AC A1C8H6;
DT 23-JAN-2007, integrated into UniProtKB/TrEMBL.
DT 23-JAN-2007, sequence version 1.
DT 27-MAR-2024, entry version 73.
DE SubName: Full=O-methyltransferase, putative {ECO:0000313|EMBL:EAW13613.1};
GN ORFNames=ACLA_043320 {ECO:0000313|EMBL:EAW13613.1};
OS Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 /
OS NRRL 1 / QM 1276 / 107).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Fumigati.
OX NCBI_TaxID=344612 {ECO:0000313|EMBL:EAW13613.1, ECO:0000313|Proteomes:UP000006701};
RN [1] {ECO:0000313|EMBL:EAW13613.1, ECO:0000313|Proteomes:UP000006701}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1
RC {ECO:0000313|Proteomes:UP000006701};
RX PubMed=18404212; DOI=10.1371/journal.pgen.1000046;
RA Fedorova N.D., Khaldi N., Joardar V.S., Maiti R., Amedeo P., Anderson M.J.,
RA Crabtree J., Silva J.C., Badger J.H., Albarraq A., Angiuoli S., Bussey H.,
RA Bowyer P., Cotty P.J., Dyer P.S., Egan A., Galens K., Fraser-Liggett C.M.,
RA Haas B.J., Inman J.M., Kent R., Lemieux S., Malavazi I., Orvis J.,
RA Roemer T., Ronning C.M., Sundaram J.P., Sutton G., Turner G., Venter J.C.,
RA White O.R., Whitty B.R., Youngman P., Wolfe K.H., Goldman G.H.,
RA Wortman J.R., Jiang B., Denning D.W., Nierman W.C.;
RT "Genomic islands in the pathogenic filamentous fungus Aspergillus
RT fumigatus.";
RL PLoS Genet. 4:E1000046-E1000046(2008).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; DS027046; EAW13613.1; -; Genomic_DNA.
DR RefSeq; XP_001275039.1; XM_001275038.1.
DR AlphaFoldDB; A1C8H6; -.
DR EnsemblFungi; EAW13613; EAW13613; ACLA_043320.
DR GeneID; 4707304; -.
DR KEGG; act:ACLA_043320; -.
DR VEuPathDB; FungiDB:ACLA_043320; -.
DR eggNOG; KOG3178; Eukaryota.
DR HOGENOM; CLU_005533_5_2_1; -.
DR OMA; HMPAHLK; -.
DR OrthoDB; 1067404at2759; -.
DR Proteomes; UP000006701; Unassembled WGS sequence.
DR GO; GO:0008171; F:O-methyltransferase activity; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0044550; P:secondary metabolite biosynthetic process; IEA:UniProt.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR016461; COMT-like.
DR InterPro; IPR001077; O_MeTrfase_dom.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR43712:SF1; HYPOTHETICAL O-METHYLTRANSFERASE (EUROFUNG)-RELATED; 1.
DR PANTHER; PTHR43712; PUTATIVE (AFU_ORTHOLOGUE AFUA_4G14580)-RELATED; 1.
DR Pfam; PF00891; Methyltransf_2; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51683; SAM_OMT_II; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW Reference proteome {ECO:0000313|Proteomes:UP000006701};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022603}.
FT DOMAIN 190..392
FT /note="O-methyltransferase"
FT /evidence="ECO:0000259|Pfam:PF00891"
SQ SEQUENCE 413 AA; 46180 MW; E4251BB42CD312F6 CRC64;
MAITEETDQY LSGVQKALQR LNGAAERCQS TLLSGQDNSL ASCSARQTVR DDLVLEALKF
LQMAQGPVDA AATCYERTAH FASVRALLEM GAFEALPTGG VSRSTQELAK ELKVDESLLA
RLLRNSSLYG PFEETGPGQY CHTPFSEAYL RPEIRGMFRF AMDDHMPAHL KLHEFLQRNG
WQEPSSTTDN PYTHAHVTNG KSMFMNLSEK PERMQAFNNG MTLQAITPLW MTDLFPWKNL
SRFQPDASTV VAVDIGGGKG KAIARIKGLC GLPGRYILQD QGHVIQSVEG VLDPKIERMG
YDFFTEQPVR GALSYLIRRC LHNWPQESVV RILKNVAAAM EPKKSCLLIE EIIVPAEKMG
VEEGWMDMIM MSLGAKQRTL KEWQTVLDLA GLEVKQVYQI PGNCHGLIEA WRK
//
