ID A1CH62_ASPCL Unreviewed; 614 AA.
AC A1CH62;
DT 23-JAN-2007, integrated into UniProtKB/TrEMBL.
DT 23-JAN-2007, sequence version 1.
DT 27-MAR-2024, entry version 91.
DE SubName: Full=SnRNP assembly factor, putative {ECO:0000313|EMBL:EAW10217.1};
GN ORFNames=ACLA_046830 {ECO:0000313|EMBL:EAW10217.1};
OS Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 /
OS NRRL 1 / QM 1276 / 107).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Fumigati.
OX NCBI_TaxID=344612 {ECO:0000313|EMBL:EAW10217.1, ECO:0000313|Proteomes:UP000006701};
RN [1] {ECO:0000313|EMBL:EAW10217.1, ECO:0000313|Proteomes:UP000006701}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1
RC {ECO:0000313|Proteomes:UP000006701};
RX PubMed=18404212; DOI=10.1371/journal.pgen.1000046;
RA Fedorova N.D., Khaldi N., Joardar V.S., Maiti R., Amedeo P., Anderson M.J.,
RA Crabtree J., Silva J.C., Badger J.H., Albarraq A., Angiuoli S., Bussey H.,
RA Bowyer P., Cotty P.J., Dyer P.S., Egan A., Galens K., Fraser-Liggett C.M.,
RA Haas B.J., Inman J.M., Kent R., Lemieux S., Malavazi I., Orvis J.,
RA Roemer T., Ronning C.M., Sundaram J.P., Sutton G., Turner G., Venter J.C.,
RA White O.R., Whitty B.R., Youngman P., Wolfe K.H., Goldman G.H.,
RA Wortman J.R., Jiang B., Denning D.W., Nierman W.C.;
RT "Genomic islands in the pathogenic filamentous fungus Aspergillus
RT fumigatus.";
RL PLoS Genet. 4:E1000046-E1000046(2008).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; DS027054; EAW10217.1; -; Genomic_DNA.
DR RefSeq; XP_001271643.1; XM_001271642.1.
DR AlphaFoldDB; A1CH62; -.
DR STRING; 344612.A1CH62; -.
DR EnsemblFungi; EAW10217; EAW10217; ACLA_046830.
DR GeneID; 4704415; -.
DR KEGG; act:ACLA_046830; -.
DR VEuPathDB; FungiDB:ACLA_046830; -.
DR eggNOG; KOG2026; Eukaryota.
DR HOGENOM; CLU_016848_2_1_1; -.
DR OMA; NKFVAER; -.
DR OrthoDB; 719409at2759; -.
DR Proteomes; UP000006701; Unassembled WGS sequence.
DR GO; GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
DR GO; GO:0004843; F:cysteine-type deubiquitinase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0000245; P:spliceosomal complex assembly; IEA:InterPro.
DR CDD; cd02669; Peptidase_C19M; 1.
DR Gene3D; 3.90.70.10; Cysteine proteinases; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR001394; Peptidase_C19_UCH.
DR InterPro; IPR033809; USP39.
DR InterPro; IPR028889; USP_dom.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR001607; Znf_UBP.
DR PANTHER; PTHR21646:SF16; U4_U6.U5 TRI-SNRNP-ASSOCIATED PROTEIN 2; 1.
DR PANTHER; PTHR21646; UBIQUITIN CARBOXYL-TERMINAL HYDROLASE; 1.
DR Pfam; PF00443; UCH; 1.
DR Pfam; PF02148; zf-UBP; 1.
DR SMART; SM00290; ZnF_UBP; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50235; USP_3; 1.
DR PROSITE; PS50271; ZF_UBP; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW mRNA processing {ECO:0000256|ARBA:ARBA00022664};
KW mRNA splicing {ECO:0000256|ARBA:ARBA00023187};
KW Reference proteome {ECO:0000313|Proteomes:UP000006701};
KW Spliceosome {ECO:0000256|ARBA:ARBA00022728};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00502}.
FT DOMAIN 107..204
FT /note="UBP-type"
FT /evidence="ECO:0000259|PROSITE:PS50271"
FT DOMAIN 229..599
FT /note="USP"
FT /evidence="ECO:0000259|PROSITE:PS50235"
FT REGION 1..102
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 22..58
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 65..84
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 614 AA; 68824 MW; 782F25CAD10E13A3 CRC64;
MSKRQAELSL EDEPAVGSPV SKKARVEDEF DENDPRNRAL PLRRATGQEM EEHERNGQNI
LAAADLEEEE MEEAIPENAD VAESSDVDDD RPAIAAPKRQ SEPMEGYSDL YLDTINRQIL
DFDFEKQCSI TLSNINVYAC LVCGKYFQGR GPKSHAYFHA LEVGHHVFIN MSTKKVYVLP
EGYEVKNKSL EDIKYVVDPH YTKEEVSKLD KQVQDAFDLA GNRYRPGFVG MNNIKANDYL
NVVVQLLAHV FPVRNYFLLH EFPTPGTPQL ALRFSTLVRK LWNPKAFRSH VSPHELLQEI
ALRSSKRFTL TQQSDPVEFL SWFLNNLHLS LGGSKKPTAT PTSVIHAAFQ GHLRIESQAI
TAHSDTQNAR LVFTESGTIN SQKTPFLILT LDLPPTPLFQ SANRESIIPQ VPLTTLLNKY
NGITASEKLA HRVRHRLLHP LPPYLLFHIK RFSKNRFVSE RNPTIVTFPS PRSLDMSPYV
EPNPDIWPPG EPILYDLVAN IILDPTVAAP GATEDAAEKG VNAAGGSSSA GAGAGSERVA
WLVQLHDKAM AAENVRHQSQ GAGEHQGPEW LEIQDLFVNK AESETLFTRE GYLMVWERRK
TPGMANRKGK NAGK
//
