ID A1CLI2_ASPCL Unreviewed; 481 AA.
AC A1CLI2;
DT 23-JAN-2007, integrated into UniProtKB/TrEMBL.
DT 23-JAN-2007, sequence version 1.
DT 24-JAN-2024, entry version 55.
DE SubName: Full=DUF895 domain membrane protein {ECO:0000313|EMBL:EAW10006.1};
GN ORFNames=ACLA_042280 {ECO:0000313|EMBL:EAW10006.1};
OS Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 /
OS NRRL 1 / QM 1276 / 107).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Fumigati.
OX NCBI_TaxID=344612 {ECO:0000313|EMBL:EAW10006.1, ECO:0000313|Proteomes:UP000006701};
RN [1] {ECO:0000313|EMBL:EAW10006.1, ECO:0000313|Proteomes:UP000006701}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1
RC {ECO:0000313|Proteomes:UP000006701};
RX PubMed=18404212; DOI=10.1371/journal.pgen.1000046;
RA Fedorova N.D., Khaldi N., Joardar V.S., Maiti R., Amedeo P., Anderson M.J.,
RA Crabtree J., Silva J.C., Badger J.H., Albarraq A., Angiuoli S., Bussey H.,
RA Bowyer P., Cotty P.J., Dyer P.S., Egan A., Galens K., Fraser-Liggett C.M.,
RA Haas B.J., Inman J.M., Kent R., Lemieux S., Malavazi I., Orvis J.,
RA Roemer T., Ronning C.M., Sundaram J.P., Sutton G., Turner G., Venter J.C.,
RA White O.R., Whitty B.R., Youngman P., Wolfe K.H., Goldman G.H.,
RA Wortman J.R., Jiang B., Denning D.W., Nierman W.C.;
RT "Genomic islands in the pathogenic filamentous fungus Aspergillus
RT fumigatus.";
RL PLoS Genet. 4:E1000046-E1000046(2008).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; DS027056; EAW10006.1; -; Genomic_DNA.
DR RefSeq; XP_001271432.1; XM_001271431.1.
DR AlphaFoldDB; A1CLI2; -.
DR EnsemblFungi; EAW10006; EAW10006; ACLA_042280.
DR GeneID; 4702686; -.
DR KEGG; act:ACLA_042280; -.
DR VEuPathDB; FungiDB:ACLA_042280; -.
DR eggNOG; KOG3098; Eukaryota.
DR HOGENOM; CLU_030884_2_0_1; -.
DR OMA; FIGIKWT; -.
DR OrthoDB; 1448322at2759; -.
DR Proteomes; UP000006701; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR010291; Ion_channel_UNC-93.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR23294:SF19; DUF895 DOMAIN MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_3G15000); 1.
DR PANTHER; PTHR23294; ET TRANSLATION PRODUCT-RELATED; 1.
DR Pfam; PF05978; UNC-93; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000006701};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 50..70
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 82..102
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 109..127
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 139..164
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 176..197
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 209..229
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 267..292
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 298..319
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 331..353
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 373..392
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 437..455
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..35
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..24
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 481 AA; 53118 MW; BBCB9FBA55BE2059 CRC64;
MTSTEKDIRP IDEEIAHSPS PEPKKYPGRR TLQPHNTVPN RSVKWYRSTF YNALILGICN
LLAPGIWGAM NSLGAGGAEK PYLVNTANAL TFCLMVVTCF FGSAIVRLIG IKWTLIVGTM
GYAPYAAGLY TNNRYGTEWF VLLGAALCGL SAGIFWMAEA AIALSYPEPH NQGRFLGFWL
SFRVGGQILG GAINLGINSS RAQAGSVSYT VYLVFIALQA LGPFAGLLLS QPAQVQRTDG
IPVRLHISHR PLYELRAMTK QFLRRDFLLI VPLIVQAVFT EAIMFTFLSL WFSVRARALG
SFLSGIIALL VGNLLGAFLD TRRLSLRARS RGAFIVILGL QGAWWVWATV IVTEYHRTRP
TYDWVDSGFG RGFALYLFWV AGFQLNYMYL YFVVSNLASN EEEVIRLASL LRGTESAAQA
VSYGLDSVHI MGSVGSSYLN FGLWAIALLP AWLVVKEIGV SLGDKKVERE ARQLENRGGE
E
//
