ID   A1CTH5_ASPCL            Unreviewed;       899 AA.
AC   A1CTH5;
DT   23-JAN-2007, integrated into UniProtKB/TrEMBL.
DT   23-JAN-2007, sequence version 1.
DT   27-MAR-2024, entry version 70.
DE   SubName: Full=Lipase/esterase family protein {ECO:0000313|EMBL:EAW06612.1};
GN   ORFNames=ACLA_083060 {ECO:0000313|EMBL:EAW06612.1};
OS   Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 /
OS   NRRL 1 / QM 1276 / 107).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Fumigati.
OX   NCBI_TaxID=344612 {ECO:0000313|EMBL:EAW06612.1, ECO:0000313|Proteomes:UP000006701};
RN   [1] {ECO:0000313|EMBL:EAW06612.1, ECO:0000313|Proteomes:UP000006701}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1
RC   {ECO:0000313|Proteomes:UP000006701};
RX   PubMed=18404212; DOI=10.1371/journal.pgen.1000046;
RA   Fedorova N.D., Khaldi N., Joardar V.S., Maiti R., Amedeo P., Anderson M.J.,
RA   Crabtree J., Silva J.C., Badger J.H., Albarraq A., Angiuoli S., Bussey H.,
RA   Bowyer P., Cotty P.J., Dyer P.S., Egan A., Galens K., Fraser-Liggett C.M.,
RA   Haas B.J., Inman J.M., Kent R., Lemieux S., Malavazi I., Orvis J.,
RA   Roemer T., Ronning C.M., Sundaram J.P., Sutton G., Turner G., Venter J.C.,
RA   White O.R., Whitty B.R., Youngman P., Wolfe K.H., Goldman G.H.,
RA   Wortman J.R., Jiang B., Denning D.W., Nierman W.C.;
RT   "Genomic islands in the pathogenic filamentous fungus Aspergillus
RT   fumigatus.";
RL   PLoS Genet. 4:E1000046-E1000046(2008).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; DS027060; EAW06612.1; -; Genomic_DNA.
DR   RefSeq; XP_001268038.1; XM_001268037.1.
DR   AlphaFoldDB; A1CTH5; -.
DR   EnsemblFungi; EAW06612; EAW06612; ACLA_083060.
DR   GeneID; 4699772; -.
DR   KEGG; act:ACLA_083060; -.
DR   VEuPathDB; FungiDB:ACLA_083060; -.
DR   eggNOG; KOG1515; Eukaryota.
DR   HOGENOM; CLU_004893_0_1_1; -.
DR   OMA; PHWVRTE; -.
DR   OrthoDB; 1943592at2759; -.
DR   Proteomes; UP000006701; Unassembled WGS sequence.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR013094; AB_hydrolase_3.
DR   PANTHER; PTHR48081; AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C; 1.
DR   PANTHER; PTHR48081:SF35; AB HYDROLASE SUPERFAMILY PROTEIN C4A8.06C; 1.
DR   Pfam; PF07859; Abhydrolase_3; 1.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000006701}.
FT   DOMAIN          160..241
FT                   /note="Alpha/beta hydrolase fold-3"
FT                   /evidence="ECO:0000259|Pfam:PF07859"
FT   REGION          482..518
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          642..700
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          716..745
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          775..794
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        485..510
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        642..682
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        683..700
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   899 AA;  98763 MW;  9ADB3308424E487C CRC64;
     MPLNTVALGA ALTPTVVATL FSHFLHRKSR QSKPTVHISY DEGIQIIREF LTYASKHPVE
     DLQAFTAQRV PAPHWVKTDK VTISENHLSS AATTIINQLG SKGVSRVGGE KWWQWRGPSD
     GLKGEWIEMK KDYNERKRAK GDYPSQKRIM LYIHGGAYFF GTEYRLAPQF PFPCALQDCL
     AAYLYLLDEH DPKNIIFAGD SAGGGMVLSI LVILRDQGLP LPAGAILISP WVDLTHSFPS
     VVSDCPGDYI PPNGFRHKPS AAWPPPNADE IEAMRKSAGK SSSKSVVEQI LLNKNSEAHE
     TAVKGYSVEQ GGPEAMEPAF PGTQATIHDG CGNIKIPIEG KTIELKDQIQ MYVTNQLISH
     PLVSPVLQPS LGGLPPLQIL VGGGERLRDE QFYLAHKAAN PTAYSPSNAF LDQYDPTREI
     LHKYPGTYVQ LQVWDDLCHV TPALSFTRPA KYMYRSIAQF GAWALACAQT SGIDIIDDDE
     ISPISSTDTD GPSAATKGVQ KQNTDISTAS VGRAGDPLPS FRDRMIRQRV DKRGHIYPLE
     PPASYAVLQR SKSHIGTMNP HLVTKWISSK QEWDIKFAKA KLRVQRQRLK ELAHGFQDFE
     GETPPPSSLA ARRLAPGVIP AEKARMGRKS YPMTMWSRIA SKHDERTLER ERQLGDRSRR
     KSVECGRAGE SMGKEKPENR IESFPTEQPS GSDVQKQPTS DAQGLALVDA GITSHKISKQ
     EPIDAAGNLS EDEPSRQDTL SIGKSSNPLI LLPEYESRQF TRENASTTTL LHAAGTLPAT
     SDNQRPASQA GSGTVRSVLT ADLEETSTID DQRSLALTTT TGLDNASTRA VRNSKGVVSL
     MNHGNSTNDS VDAFSAARRS GDLDSFYSIN ANTEGDAYSY IGRPDMPDRD VFKTADEYH
//