ID A1CW43_NEOFI Unreviewed; 733 AA.
AC A1CW43;
DT 23-JAN-2007, integrated into UniProtKB/TrEMBL.
DT 23-JAN-2007, sequence version 1.
DT 27-MAR-2024, entry version 87.
DE SubName: Full=CCCH zinc finger and SMR domain protein {ECO:0000313|EMBL:EAW24845.1};
GN ORFNames=NFIA_103330 {ECO:0000313|EMBL:EAW24845.1};
OS Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164
OS / JCM 1740 / NRRL 181 / WB 181) (Aspergillus fischerianus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Fumigati.
OX NCBI_TaxID=331117 {ECO:0000313|EMBL:EAW24845.1, ECO:0000313|Proteomes:UP000006702};
RN [1] {ECO:0000313|Proteomes:UP000006702}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 /
RC NRRL 181 / WB 181 {ECO:0000313|Proteomes:UP000006702};
RX PubMed=18404212; DOI=10.1371/journal.pgen.1000046;
RA Fedorova N.D., Khaldi N., Joardar V.S., Maiti R., Amedeo P., Anderson M.J.,
RA Crabtree J., Silva J.C., Badger J.H., Albarraq A., Angiuoli S., Bussey H.,
RA Bowyer P., Cotty P.J., Dyer P.S., Egan A., Galens K., Fraser-Liggett C.M.,
RA Haas B.J., Inman J.M., Kent R., Lemieux S., Malavazi I., Orvis J.,
RA Roemer T., Ronning C.M., Sundaram J.P., Sutton G., Turner G., Venter J.C.,
RA White O.R., Whitty B.R., Youngman P., Wolfe K.H., Goldman G.H.,
RA Wortman J.R., Jiang B., Denning D.W., Nierman W.C.;
RT "Genomic islands in the pathogenic filamentous fungus Aspergillus
RT fumigatus.";
RL PLoS Genet. 4:E1000046-E1000046(2008).
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DR EMBL; DS027685; EAW24845.1; -; Genomic_DNA.
DR RefSeq; XP_001266742.1; XM_001266741.1.
DR AlphaFoldDB; A1CW43; -.
DR STRING; 331117.A1CW43; -.
DR EnsemblFungi; EAW24845; EAW24845; NFIA_103330.
DR GeneID; 4593261; -.
DR KEGG; nfi:NFIA_103330; -.
DR VEuPathDB; FungiDB:NFIA_103330; -.
DR eggNOG; KOG2401; Eukaryota.
DR HOGENOM; CLU_015244_0_0_1; -.
DR OMA; WRHRNRN; -.
DR OrthoDB; 11936at2759; -.
DR Proteomes; UP000006702; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR GO; GO:0045892; P:negative regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 3.30.1370.110; -; 1.
DR Gene3D; 4.10.1000.10; Zinc finger, CCCH-type; 1.
DR InterPro; IPR013899; DUF1771.
DR InterPro; IPR002625; Smr_dom.
DR InterPro; IPR036063; Smr_dom_sf.
DR InterPro; IPR045124; Su(sable)-like.
DR InterPro; IPR000571; Znf_CCCH.
DR InterPro; IPR036855; Znf_CCCH_sf.
DR PANTHER; PTHR13119:SF12; PROTEIN SUPPRESSOR OF SABLE; 1.
DR PANTHER; PTHR13119; ZINC FINGER CCCH DOMAIN-CONTAINING PROTEI; 1.
DR Pfam; PF08590; DUF1771; 1.
DR Pfam; PF01713; Smr; 1.
DR Pfam; PF14608; zf-CCCH_2; 2.
DR SMART; SM01162; DUF1771; 1.
DR SMART; SM00463; SMR; 1.
DR SMART; SM00356; ZnF_C3H1; 2.
DR SUPFAM; SSF90229; CCCH zinc finger; 1.
DR SUPFAM; SSF160443; SMR domain-like; 1.
DR PROSITE; PS50828; SMR; 1.
DR PROSITE; PS50103; ZF_C3H1; 2.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723, ECO:0000256|PROSITE-
KW ProRule:PRU00723}; mRNA processing {ECO:0000256|ARBA:ARBA00022664};
KW Reference proteome {ECO:0000313|Proteomes:UP000006702};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|PROSITE-ProRule:PRU00723};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00723}.
FT DOMAIN 277..304
FT /note="C3H1-type"
FT /evidence="ECO:0000259|PROSITE:PS50103"
FT DOMAIN 307..329
FT /note="C3H1-type"
FT /evidence="ECO:0000259|PROSITE:PS50103"
FT DOMAIN 604..687
FT /note="Smr"
FT /evidence="ECO:0000259|PROSITE:PS50828"
FT ZN_FING 277..304
FT /note="C3H1-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00723"
FT ZN_FING 307..329
FT /note="C3H1-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00723"
FT REGION 56..139
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 381..514
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 698..719
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 79..126
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 384..398
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 495..514
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 733 AA; 79877 MW; 5EECC5FE88B34582 CRC64;
MISDDLLDSC FQILQDKALD EEEQAEKVES FLRENTSLSG ASLENAVLDV LWRHRNRTLP
DSSPPPPRHT VIRRTSPAPW QMARSSTPLS PPSNLGTSPG GSSWFQSSRG FSRAPLSSTV
SPFTSPRPSP RLALAQPIPH SPNLNAYEFS DQSQVSDFYS DFGNDSNVDW LVADDAQSTT
SSVGTMSASG ALSATAPEFV PDMSPHDILR TVLGDKRSNE EIEAALEANG YDLGATIASL
SQDQSGGSFS QSDDGRVVVG KSMTMEQPRL STSPNHNRSP VVCKYWLSTG QCLRADCRFS
HDLTNHVCKY WIMGNCLAGD GCPFSHDPSA LIANLSVGES NQQGGPTFNV ENTSEAFPPL
QSAGGVGEQW TNHYLGKYPH LSGSAGNKSP QAMQLTPGKR NGHGSRPHSR PTSRHQHREL
NSTALSVDDP DAFPSLAAVS AKNASKKHGK RNNRETGSVK ETLPTSLADV VRMSPSPAPG
KGKPTSKNSR EGTKSRENSA AAQSIPAPQN IPWLETGSRA NQQYIKYRTE AIRHGTVRNK
FLQSAAQAWN RNDARAAKAL SLRGQAENEA MRKCHREAAR QLYEERNKHL LSAGLDESSE
ELYVDLHGLH PEEAIEYLEK ILLKHAREGR RVIYAITGTG HHSKNGKDKI GKAVKAWLNE
WKYLYREFSV PGERGGYVGG ILGIDPTSYD KTLAKSLEEG EDGKGGDSNG NQPVMTMGKI
QLLKREDLES KSS
//
