ID A1CX04_NEOFI Unreviewed; 505 AA.
AC A1CX04;
DT 23-JAN-2007, integrated into UniProtKB/TrEMBL.
DT 23-JAN-2007, sequence version 1.
DT 24-JAN-2024, entry version 66.
DE SubName: Full=ZIP Zinc transporter, putative {ECO:0000313|EMBL:EAW25156.1};
GN ORFNames=NFIA_106440 {ECO:0000313|EMBL:EAW25156.1};
OS Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164
OS / JCM 1740 / NRRL 181 / WB 181) (Aspergillus fischerianus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Fumigati.
OX NCBI_TaxID=331117 {ECO:0000313|EMBL:EAW25156.1, ECO:0000313|Proteomes:UP000006702};
RN [1] {ECO:0000313|Proteomes:UP000006702}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 /
RC NRRL 181 / WB 181 {ECO:0000313|Proteomes:UP000006702};
RX PubMed=18404212; DOI=10.1371/journal.pgen.1000046;
RA Fedorova N.D., Khaldi N., Joardar V.S., Maiti R., Amedeo P., Anderson M.J.,
RA Crabtree J., Silva J.C., Badger J.H., Albarraq A., Angiuoli S., Bussey H.,
RA Bowyer P., Cotty P.J., Dyer P.S., Egan A., Galens K., Fraser-Liggett C.M.,
RA Haas B.J., Inman J.M., Kent R., Lemieux S., Malavazi I., Orvis J.,
RA Roemer T., Ronning C.M., Sundaram J.P., Sutton G., Turner G., Venter J.C.,
RA White O.R., Whitty B.R., Youngman P., Wolfe K.H., Goldman G.H.,
RA Wortman J.R., Jiang B., Denning D.W., Nierman W.C.;
RT "Genomic islands in the pathogenic filamentous fungus Aspergillus
RT fumigatus.";
RL PLoS Genet. 4:E1000046-E1000046(2008).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; DS027685; EAW25156.1; -; Genomic_DNA.
DR RefSeq; XP_001267053.1; XM_001267052.1.
DR AlphaFoldDB; A1CX04; -.
DR STRING; 331117.A1CX04; -.
DR EnsemblFungi; EAW25156; EAW25156; NFIA_106440.
DR GeneID; 4593410; -.
DR KEGG; nfi:NFIA_106440; -.
DR VEuPathDB; FungiDB:NFIA_106440; -.
DR eggNOG; KOG1558; Eukaryota.
DR HOGENOM; CLU_027089_5_0_1; -.
DR OMA; QYTGCHS; -.
DR OrthoDB; 1112460at2759; -.
DR Proteomes; UP000006702; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0046873; F:metal ion transmembrane transporter activity; IEA:InterPro.
DR InterPro; IPR003689; ZIP.
DR PANTHER; PTHR11040:SF44; PROTEIN ZNTC; 1.
DR PANTHER; PTHR11040; ZINC/IRON TRANSPORTER; 1.
DR Pfam; PF02535; Zip; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000006702};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..16
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 17..505
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002633255"
FT TRANSMEM 195..218
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 230..248
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 268..287
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 348..372
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 378..399
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 411..434
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 440..462
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 483..502
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 125..155
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 298..339
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 132..151
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 305..328
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 505 AA; 52557 MW; B63E9C80F3BFBE5C CRC64;
MAKALLLLSL LGLAHAQYVT YTGCHNHGST EYCFGPDGKE TPFPTPTPSA SKTVPVTAAA
STTASADASA VTGCHSHGSD VFCIDGDGHE VQVILPSTPT GELPAQYTGC HSHGGETFCM
DPEGNDVQIV GEGGSTGASS SSGSSEESHS GSKEGMNCHF HAGVEHCVGA GESESGSSQK
SCGLRNRDYD VPLRIGTLFV VLVTSSIGVF LPMLLVKLPS AKINGVVSTV IKQFGTGVIL
STAFVHLYTH ANLMFTNECL GELEYEATTS AVVMAGIFLS FLFEYIGHRI ILARGKRSAS
PCPEHTGEVS PSSTSKEPPS NQPQQPTLAA LGHHHGPPLD PTNPNTKLSV LVMEAGVIFH
SILIGLTLVV AGDSFYKTLL VVIIFHQFFE GLALGARIAM LPGRLLGSKG LMAGAFAVIT
PIGMAIGLGV LHSFNGNDQS TLVALGTLDA LSAGILVWVG LVDMWARDWV MEGGEMMDAT
MSSVAVGGFS LIAGMVLMGV LGKWA
//
