ID A1CZK1_NEOFI Unreviewed; 724 AA.
AC A1CZK1;
DT 23-JAN-2007, integrated into UniProtKB/TrEMBL.
DT 23-JAN-2007, sequence version 1.
DT 27-MAR-2024, entry version 99.
DE SubName: Full=Forkhead transcription factor (Sep1), putative {ECO:0000313|EMBL:EAW24171.1};
GN ORFNames=NFIA_037450 {ECO:0000313|EMBL:EAW24171.1};
OS Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164
OS / JCM 1740 / NRRL 181 / WB 181) (Aspergillus fischerianus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Fumigati.
OX NCBI_TaxID=331117 {ECO:0000313|EMBL:EAW24171.1, ECO:0000313|Proteomes:UP000006702};
RN [1] {ECO:0000313|Proteomes:UP000006702}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 /
RC NRRL 181 / WB 181 {ECO:0000313|Proteomes:UP000006702};
RX PubMed=18404212; DOI=10.1371/journal.pgen.1000046;
RA Fedorova N.D., Khaldi N., Joardar V.S., Maiti R., Amedeo P., Anderson M.J.,
RA Crabtree J., Silva J.C., Badger J.H., Albarraq A., Angiuoli S., Bussey H.,
RA Bowyer P., Cotty P.J., Dyer P.S., Egan A., Galens K., Fraser-Liggett C.M.,
RA Haas B.J., Inman J.M., Kent R., Lemieux S., Malavazi I., Orvis J.,
RA Roemer T., Ronning C.M., Sundaram J.P., Sutton G., Turner G., Venter J.C.,
RA White O.R., Whitty B.R., Youngman P., Wolfe K.H., Goldman G.H.,
RA Wortman J.R., Jiang B., Denning D.W., Nierman W.C.;
RT "Genomic islands in the pathogenic filamentous fungus Aspergillus
RT fumigatus.";
RL PLoS Genet. 4:E1000046-E1000046(2008).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00089}.
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DR EMBL; DS027686; EAW24171.1; -; Genomic_DNA.
DR RefSeq; XP_001266068.1; XM_001266067.1.
DR AlphaFoldDB; A1CZK1; -.
DR STRING; 331117.A1CZK1; -.
DR EnsemblFungi; EAW24171; EAW24171; NFIA_037450.
DR GeneID; 4593210; -.
DR KEGG; nfi:NFIA_037450; -.
DR VEuPathDB; FungiDB:NFIA_037450; -.
DR eggNOG; KOG2294; Eukaryota.
DR HOGENOM; CLU_012536_0_0_1; -.
DR OMA; PNDAGWQ; -.
DR OrthoDB; 5385885at2759; -.
DR Proteomes; UP000006702; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:UniProt.
DR CDD; cd00059; FH_FOX; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR001766; Fork_head_dom.
DR InterPro; IPR030456; TF_fork_head_CS_2.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11829:SF343; FORK HEAD DOMAIN TRANSCRIPTION FACTOR SLP1-RELATED; 1.
DR PANTHER; PTHR11829; FORKHEAD BOX PROTEIN; 1.
DR Pfam; PF00250; Forkhead; 1.
DR PRINTS; PR00053; FORKHEAD.
DR SMART; SM00339; FH; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00658; FORK_HEAD_2; 1.
DR PROSITE; PS50039; FORK_HEAD_3; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00089}; Nucleus {ECO:0000256|PROSITE-ProRule:PRU00089};
KW Reference proteome {ECO:0000313|Proteomes:UP000006702}.
FT DOMAIN 211..306
FT /note="Fork-head"
FT /evidence="ECO:0000259|PROSITE:PS50039"
FT DNA_BIND 211..306
FT /note="Fork-head"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00089"
FT REGION 1..118
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 134..162
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 308..460
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 640..659
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 694..724
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 27..46
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 102..118
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 308..357
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 369..384
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 385..413
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 419..442
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 709..724
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 724 AA; 79285 MW; 8520C9654B3D3FC8 CRC64;
MNPTCSGPFV PPLSEPAAEY DKKVSQSHSQ HLSSSCSSSL PLQPPENVRS GQECILDPPL
SSALRPSPMK TPRGLKTSLS GRRELGFIPI TAPAPPKFTT DSPAKRTPST TYPCNTASSS
AMPQSALFTT FPSVNHGKQS SKEKRQMAES CNDNFADFPE PSFASKPLKR TLMDAAPLKE
RTIKKQKRED VDVTRLPTPQ EMTPIEDDGT KPPYSYATLI GMSILRAPNR RLTLAQIYKW
ISDTFSYYKH SDPGWQNSIR HNLSLNKAFI KQERPKDDPG KGNYWAIEPG MEAQFLKDKP
LRRATMSSLP LPVTSQREPA HTQSSGTTTW AIPPPNHTLV PKSSQNVDLS SDATIPASDP
ALQDDMSDEG VNAATSQAPL RSSPPQPIRS SPPIAPPRFI RQGTPPTPSH PTPSAIVPHS
RKRESTTIND SGYFSSLESS AMRPKKTGPI LTSDLDIDPP RIKRGRAEEE IARIRSSSHD
ISPRRPGMLK DAGVVIGSSP VRGEYVSMLP PPLTPVIKFK KPAKPPPSVS PNTNLRNHRK
KIQQMVNSPL KHLGLTDEDL PWSPAFRIQD ESYTPSDHLH ATFDVFAESA EEGISTLAYG
SPEKRPAKRA RTDTENQTGT VLADITSVSV NSKTGMQALS SAKSKGPLFP ESPSKMPEHG
RFGDATHDDF FSFHLFDESP VEVDGVDLLQ GFQKIGSSSK EESARSKSHT SRPQPNIRSN
TALF
//
