ID A1D1J9_NEOFI Unreviewed; 344 AA.
AC A1D1J9;
DT 23-JAN-2007, integrated into UniProtKB/TrEMBL.
DT 23-JAN-2007, sequence version 1.
DT 24-JAN-2024, entry version 88.
DE SubName: Full=Oxidoreductase, zinc-binding dehydrogenase family, putative {ECO:0000313|EMBL:EAW22292.1};
GN ORFNames=NFIA_009720 {ECO:0000313|EMBL:EAW22292.1};
OS Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164
OS / JCM 1740 / NRRL 181 / WB 181) (Aspergillus fischerianus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Fumigati.
OX NCBI_TaxID=331117 {ECO:0000313|EMBL:EAW22292.1, ECO:0000313|Proteomes:UP000006702};
RN [1] {ECO:0000313|Proteomes:UP000006702}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 /
RC NRRL 181 / WB 181 {ECO:0000313|Proteomes:UP000006702};
RX PubMed=18404212; DOI=10.1371/journal.pgen.1000046;
RA Fedorova N.D., Khaldi N., Joardar V.S., Maiti R., Amedeo P., Anderson M.J.,
RA Crabtree J., Silva J.C., Badger J.H., Albarraq A., Angiuoli S., Bussey H.,
RA Bowyer P., Cotty P.J., Dyer P.S., Egan A., Galens K., Fraser-Liggett C.M.,
RA Haas B.J., Inman J.M., Kent R., Lemieux S., Malavazi I., Orvis J.,
RA Roemer T., Ronning C.M., Sundaram J.P., Sutton G., Turner G., Venter J.C.,
RA White O.R., Whitty B.R., Youngman P., Wolfe K.H., Goldman G.H.,
RA Wortman J.R., Jiang B., Denning D.W., Nierman W.C.;
RT "Genomic islands in the pathogenic filamentous fungus Aspergillus
RT fumigatus.";
RL PLoS Genet. 4:E1000046-E1000046(2008).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; DS027688; EAW22292.1; -; Genomic_DNA.
DR RefSeq; XP_001264189.1; XM_001264188.1.
DR AlphaFoldDB; A1D1J9; -.
DR EnsemblFungi; EAW22292; EAW22292; NFIA_009720.
DR GeneID; 4591190; -.
DR KEGG; nfi:NFIA_009720; -.
DR VEuPathDB; FungiDB:NFIA_009720; -.
DR eggNOG; KOG1196; Eukaryota.
DR HOGENOM; CLU_026673_29_1_1; -.
DR OMA; PIKNIHN; -.
DR OrthoDB; 179761at2759; -.
DR Proteomes; UP000006702; Unassembled WGS sequence.
DR GO; GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR CDD; cd05288; PGDH; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013149; ADH-like_C.
DR InterPro; IPR041694; ADH_N_2.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR045010; MDR_fam.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020843; PKS_ER.
DR PANTHER; PTHR43205; PROSTAGLANDIN REDUCTASE; 1.
DR PANTHER; PTHR43205:SF7; PROSTAGLANDIN REDUCTASE 1; 1.
DR Pfam; PF16884; ADH_N_2; 1.
DR Pfam; PF00107; ADH_zinc_N; 1.
DR SMART; SM00829; PKS_ER; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000006702}.
FT DOMAIN 20..342
FT /note="Enoyl reductase (ER)"
FT /evidence="ECO:0000259|SMART:SM00829"
SQ SEQUENCE 344 AA; 37492 MW; CE019CF6FEA90A7B CRC64;
MSSNKALVFK KVPEGYPVPG EHLTIEPVEY DANTPAPENG VVLQSLYTSF DPYMRGRMRP
PHVKSYSPAL ELGKPIDSTT IAKVLRSNNA SFKEGDLVIG FVPIQEYIVL DGSQVARIRP
LENPLGIEDI RVFLGALGMP GLTAYSSLYE IGKPKKGETI FVSAASGAVG QLVGQLAKHE
GLKVIGSVGS DEKLEYITKD LGFDGGFNYK KEKPADALAR LAPQGIDIYY ENVGGEHLEA
ALDAMNNFGR VVVCGLISQY NTAPYPIKNI HNVLIKRIDM RGFIVSDPGM GDKYTEEHQK
NVQKWIKEGS FKALLHETTG IDNAAEGLVG IFHGKNKGKA VLKF
//
