ID A1D1R4_NEOFI Unreviewed; 748 AA.
AC A1D1R4;
DT 23-JAN-2007, integrated into UniProtKB/TrEMBL.
DT 23-JAN-2007, sequence version 1.
DT 24-JAN-2024, entry version 68.
DE RecName: Full=Protein SDA1 {ECO:0000256|RuleBase:RU365057};
GN ORFNames=NFIA_010380 {ECO:0000313|EMBL:EAW22357.1};
OS Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164
OS / JCM 1740 / NRRL 181 / WB 181) (Aspergillus fischerianus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Fumigati.
OX NCBI_TaxID=331117 {ECO:0000313|EMBL:EAW22357.1, ECO:0000313|Proteomes:UP000006702};
RN [1] {ECO:0000313|Proteomes:UP000006702}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 /
RC NRRL 181 / WB 181 {ECO:0000313|Proteomes:UP000006702};
RX PubMed=18404212; DOI=10.1371/journal.pgen.1000046;
RA Fedorova N.D., Khaldi N., Joardar V.S., Maiti R., Amedeo P., Anderson M.J.,
RA Crabtree J., Silva J.C., Badger J.H., Albarraq A., Angiuoli S., Bussey H.,
RA Bowyer P., Cotty P.J., Dyer P.S., Egan A., Galens K., Fraser-Liggett C.M.,
RA Haas B.J., Inman J.M., Kent R., Lemieux S., Malavazi I., Orvis J.,
RA Roemer T., Ronning C.M., Sundaram J.P., Sutton G., Turner G., Venter J.C.,
RA White O.R., Whitty B.R., Youngman P., Wolfe K.H., Goldman G.H.,
RA Wortman J.R., Jiang B., Denning D.W., Nierman W.C.;
RT "Genomic islands in the pathogenic filamentous fungus Aspergillus
RT fumigatus.";
RL PLoS Genet. 4:E1000046-E1000046(2008).
CC -!- FUNCTION: Required for 60S pre-ribosomal subunits export to the
CC cytoplasm. {ECO:0000256|RuleBase:RU365057}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|RuleBase:RU365057}.
CC -!- SIMILARITY: Belongs to the SDA1 family. {ECO:0000256|ARBA:ARBA00005783,
CC ECO:0000256|RuleBase:RU365057}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; DS027688; EAW22357.1; -; Genomic_DNA.
DR RefSeq; XP_001264254.1; XM_001264253.1.
DR AlphaFoldDB; A1D1R4; -.
DR STRING; 331117.A1D1R4; -.
DR EnsemblFungi; EAW22357; EAW22357; NFIA_010380.
DR GeneID; 4592020; -.
DR KEGG; nfi:NFIA_010380; -.
DR VEuPathDB; FungiDB:NFIA_010380; -.
DR eggNOG; KOG2229; Eukaryota.
DR HOGENOM; CLU_009161_2_1_1; -.
DR OMA; AMYKTYK; -.
DR OrthoDB; 5482564at2759; -.
DR Proteomes; UP000006702; Unassembled WGS sequence.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR GO; GO:0042273; P:ribosomal large subunit biogenesis; IEA:UniProtKB-UniRule.
DR GO; GO:0000055; P:ribosomal large subunit export from nucleus; IEA:UniProtKB-UniRule.
DR GO; GO:0007089; P:traversing start control point of mitotic cell cycle; IEA:EnsemblFungi.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR027312; Sda1.
DR InterPro; IPR048292; SDA1_C.
DR InterPro; IPR007949; SDA1_MD.
DR InterPro; IPR012977; SDA1_N.
DR PANTHER; PTHR12730; HSDA/SDA1-RELATED; 1.
DR PANTHER; PTHR12730:SF0; PROTEIN SDA1 HOMOLOG; 1.
DR Pfam; PF21638; SDA1_C; 1.
DR Pfam; PF05285; SDA1_dom; 1.
DR Pfam; PF08158; SDA1_HEAT; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU365057};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927,
KW ECO:0000256|RuleBase:RU365057};
KW Reference proteome {ECO:0000313|Proteomes:UP000006702};
KW Ribosome biogenesis {ECO:0000256|ARBA:ARBA00022517,
KW ECO:0000256|RuleBase:RU365057};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU365057}.
FT DOMAIN 69..437
FT /note="SDA1 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF08158"
FT DOMAIN 549..673
FT /note="SDA1 middle"
FT /evidence="ECO:0000259|Pfam:PF05285"
FT DOMAIN 695..740
FT /note="SDA1 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF21638"
FT REGION 466..487
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 505..604
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 620..748
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 517..548
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 565..590
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 662..708
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 748 AA; 84675 MW; 9697811F563C610E CRC64;
MVKRKLGALE KVEADLPNLQ HKIRRDPKSY IEDFRAQHYQ YESHREIFMA APTAATDTGI
ISLRELIDFI AHVADCYPTI TKDFSQQLID ILTQHHLVLE PELREKIVGS LVLLRKKELL
DSATLLQTLF PILITTPSKT LRALIFQKIL MDLRSSNAKT TNHKLNRTMQ TVLFNLVTSD
RTSSKGLWAI KLTRELWKRQ IWTDAKAVEV MKEACLSENE KVIVGGVRFF LGGDKEREEM
EDESSDEETI DLGRVKHQVG INKKTRKKSR AVEKAKAIVK KRERKKNQPH PLNFSALHLL
HDPQGFAEAL FAKHLQNTKS NLNLEQKLLV LQLVSRLVGL HRLHIMHLYS YFQKYLTPRQ
ASVTSFLASL AQASHDLVPP DVLEPLVQKI ANEFVSEAAA SEVATAGLNA IREICARQPL
AMNETLLQDL VMYRKSKDKG VVMAARGLLS LYRDVGADML KRRDRGKEAS MSLRAGEKKE
RRFGEQQTGE IEGLELLEKW KEEERRKRRI EKGLPSDAED DEDDEAEDDA AWDKWNIEDD
EDSDDSGGWI DVQSDAEIEL SDSDDDQSPP AKKAKQGDEE EDKANSETAR PETKKTNLAT
TRILTPADLA KLAELRSEAA VNSLLPKRLR SDQKNGPSRH ADDPLTAAEI EGLAALSAGK
ATREERIAHA KEGKDRSEYK SVTARRKERK EAQGKSTTNK EKARRKNLFM TLGKAKSKGK
RSLVETRNVL RAHQQRQKRG GRRGNTGS
//
