ID   A1D1U4_NEOFI            Unreviewed;       747 AA.
AC   A1D1U4;
DT   23-JAN-2007, integrated into UniProtKB/TrEMBL.
DT   23-JAN-2007, sequence version 1.
DT   27-MAR-2024, entry version 83.
DE   SubName: Full=Kelch repeat protein {ECO:0000313|EMBL:EAW22387.1};
GN   ORFNames=NFIA_010680 {ECO:0000313|EMBL:EAW22387.1};
OS   Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164
OS   / JCM 1740 / NRRL 181 / WB 181) (Aspergillus fischerianus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Fumigati.
OX   NCBI_TaxID=331117 {ECO:0000313|EMBL:EAW22387.1, ECO:0000313|Proteomes:UP000006702};
RN   [1] {ECO:0000313|Proteomes:UP000006702}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 /
RC   NRRL 181 / WB 181 {ECO:0000313|Proteomes:UP000006702};
RX   PubMed=18404212; DOI=10.1371/journal.pgen.1000046;
RA   Fedorova N.D., Khaldi N., Joardar V.S., Maiti R., Amedeo P., Anderson M.J.,
RA   Crabtree J., Silva J.C., Badger J.H., Albarraq A., Angiuoli S., Bussey H.,
RA   Bowyer P., Cotty P.J., Dyer P.S., Egan A., Galens K., Fraser-Liggett C.M.,
RA   Haas B.J., Inman J.M., Kent R., Lemieux S., Malavazi I., Orvis J.,
RA   Roemer T., Ronning C.M., Sundaram J.P., Sutton G., Turner G., Venter J.C.,
RA   White O.R., Whitty B.R., Youngman P., Wolfe K.H., Goldman G.H.,
RA   Wortman J.R., Jiang B., Denning D.W., Nierman W.C.;
RT   "Genomic islands in the pathogenic filamentous fungus Aspergillus
RT   fumigatus.";
RL   PLoS Genet. 4:E1000046-E1000046(2008).
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DR   EMBL; DS027688; EAW22387.1; -; Genomic_DNA.
DR   RefSeq; XP_001264284.1; XM_001264283.1.
DR   AlphaFoldDB; A1D1U4; -.
DR   STRING; 331117.A1D1U4; -.
DR   EnsemblFungi; EAW22387; EAW22387; NFIA_010680.
DR   GeneID; 4591525; -.
DR   KEGG; nfi:NFIA_010680; -.
DR   VEuPathDB; FungiDB:NFIA_010680; -.
DR   eggNOG; KOG0379; Eukaryota.
DR   eggNOG; KOG1426; Eukaryota.
DR   HOGENOM; CLU_014024_0_0_1; -.
DR   OMA; NLYDMPK; -.
DR   OrthoDB; 4030895at2759; -.
DR   Proteomes; UP000006702; Unassembled WGS sequence.
DR   CDD; cd14733; BACK; 1.
DR   Gene3D; 2.120.10.80; Kelch-type beta propeller; 1.
DR   InterPro; IPR000210; BTB/POZ_dom.
DR   InterPro; IPR015915; Kelch-typ_b-propeller.
DR   InterPro; IPR006652; Kelch_1.
DR   InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR   PANTHER; PTHR46376; LEUCINE-ZIPPER-LIKE TRANSCRIPTIONAL REGULATOR 1; 1.
DR   PANTHER; PTHR46376:SF1; LEUCINE-ZIPPER-LIKE TRANSCRIPTIONAL REGULATOR 1; 1.
DR   Pfam; PF00651; BTB; 1.
DR   Pfam; PF13415; Kelch_3; 1.
DR   Pfam; PF13418; Kelch_4; 1.
DR   Pfam; PF13854; Kelch_5; 1.
DR   SMART; SM00612; Kelch; 2.
DR   SUPFAM; SSF117281; Kelch motif; 1.
DR   SUPFAM; SSF54695; POZ domain; 1.
DR   PROSITE; PS50097; BTB; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000006702}.
FT   DOMAIN          529..598
FT                   /note="BTB"
FT                   /evidence="ECO:0000259|PROSITE:PS50097"
FT   REGION          1..64
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          718..747
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..22
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        32..53
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        733..747
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   747 AA;  82997 MW;  187449659A9C0542 CRC64;
     MARQPSSTIT SNTTSTPVFT QFREDPPSWI RSRDSNPMTP TPSVHQRPQS AYLMPTSPAR
     GRRGSTDYRP VIRKAQGNVP ACLVNASVTY CNNEQIYAFG GFDQFTDEVY NHVLRLDLKA
     LRWELVDNYG DIPGVRMGHT ATLYQGDKLI VFGGENEHRE YLSDIVILDI PTSTWTQPEI
     RGQIPRGRAR HAAVIHDEKL FIIGGVTGEN NVILDDLCYL DLKTWTWSRS WRFTARFDHT
     AWVWGDRLWI FGGLDPDMER TTDIWWLDLK GSPFLGTPSS QGTVDSPGIL NRLTHSPDTV
     YSSPTQQLPG RSGSYAANSG SVQVRNAGRK KPIAPGAISC HKFRSGPYVP ALSAGTHFQA
     HASGVLLDLI TPSETVRTYE CKLSALELDT LRWQKLADGQ EIFKPGYRWH YCTVDASGTK
     AWLLGCSLDV GAAPGNSDEN HMSEVLCIDL EKYGLLGNEL ATLSPDQSRA LVSERSGLPP
     ISGLGADLSA VFDQPPESGS DADFIITANP DDIEYPDDVA EDAPPTESQP AFLPANAPTS
     PPIHVHRIIL QLRWPHFKRL YSAQMAEYHS KRMHIPEPYS VVRAFLYYLY TDSISGHPEY
     CSSIIDVAGM LVMANLYDMP KLRLLCVNRL SRELDVENAA IIWERAGRTN EDWLMRRAAQ
     FCLSHWGRVV RTDGFKSLSR QSLIELCEVV DMEGRIVAGP ELELVGALGA EGLDLSRDTK
     RSRPSVGGAM TDVDDLEGDD VDGMEIV
//