ID A1D3A4_NEOFI Unreviewed; 255 AA.
AC A1D3A4;
DT 23-JAN-2007, integrated into UniProtKB/TrEMBL.
DT 23-JAN-2007, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE RecName: Full=VPS37 C-terminal domain-containing protein {ECO:0000259|PROSITE:PS51314};
GN ORFNames=NFIA_015900 {ECO:0000313|EMBL:EAW22897.1};
OS Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164
OS / JCM 1740 / NRRL 181 / WB 181) (Aspergillus fischerianus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Fumigati.
OX NCBI_TaxID=331117 {ECO:0000313|EMBL:EAW22897.1, ECO:0000313|Proteomes:UP000006702};
RN [1] {ECO:0000313|Proteomes:UP000006702}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 /
RC NRRL 181 / WB 181 {ECO:0000313|Proteomes:UP000006702};
RX PubMed=18404212; DOI=10.1371/journal.pgen.1000046;
RA Fedorova N.D., Khaldi N., Joardar V.S., Maiti R., Amedeo P., Anderson M.J.,
RA Crabtree J., Silva J.C., Badger J.H., Albarraq A., Angiuoli S., Bussey H.,
RA Bowyer P., Cotty P.J., Dyer P.S., Egan A., Galens K., Fraser-Liggett C.M.,
RA Haas B.J., Inman J.M., Kent R., Lemieux S., Malavazi I., Orvis J.,
RA Roemer T., Ronning C.M., Sundaram J.P., Sutton G., Turner G., Venter J.C.,
RA White O.R., Whitty B.R., Youngman P., Wolfe K.H., Goldman G.H.,
RA Wortman J.R., Jiang B., Denning D.W., Nierman W.C.;
RT "Genomic islands in the pathogenic filamentous fungus Aspergillus
RT fumigatus.";
RL PLoS Genet. 4:E1000046-E1000046(2008).
CC -!- SIMILARITY: Belongs to the VPS37 family.
CC {ECO:0000256|ARBA:ARBA00007617}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; DS027688; EAW22897.1; -; Genomic_DNA.
DR RefSeq; XP_001264794.1; XM_001264793.1.
DR AlphaFoldDB; A1D3A4; -.
DR EnsemblFungi; EAW22897; EAW22897; NFIA_015900.
DR GeneID; 4591488; -.
DR KEGG; nfi:NFIA_015900; -.
DR VEuPathDB; FungiDB:NFIA_015900; -.
DR eggNOG; ENOG502S268; Eukaryota.
DR HOGENOM; CLU_088665_0_0_1; -.
DR OMA; SWRKKQT; -.
DR OrthoDB; 2732551at2759; -.
DR Proteomes; UP000006702; Unassembled WGS sequence.
DR GO; GO:0000813; C:ESCRT I complex; IEA:UniProt.
DR GO; GO:0072666; P:establishment of protein localization to vacuole; IEA:UniProt.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-UniRule.
DR GO; GO:0043162; P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; IEA:UniProt.
DR GO; GO:0007034; P:vacuolar transport; IEA:UniProt.
DR InterPro; IPR037202; ESCRT_assembly_dom.
DR InterPro; IPR009851; Mod_r.
DR PANTHER; PTHR13678; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 37; 1.
DR PANTHER; PTHR13678:SF2; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 37A; 1.
DR Pfam; PF07200; Mod_r; 1.
DR SUPFAM; SSF140111; Endosomal sorting complex assembly domain; 1.
DR PROSITE; PS51314; VPS37_C; 1.
PE 3: Inferred from homology;
KW Endosome {ECO:0000256|ARBA:ARBA00022753};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000006702};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 164..255
FT /note="VPS37 C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51314"
FT REGION 1..40
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..19
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 20..40
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 255 AA; 28645 MW; EE5B7C14EF46E147 CRC64;
MDPALNPDTP PPPPPKPSSH ETSRRGTPQL NQSIPGTPQQ QFRGYYQAQE GKNGENRYQS
PSMTEAVHAN NINSLPKPPA VEEGWLPDVV KDKSTVDLQA ILKDPNLISA LASQHPACTA
QQQNLQSLLK YNQDLTKHLL ELQARLDEQR ASTETLLLKH QSLEVSWRKK QSEMDAALAP
WSPKALYQRL SASISEQEAV CRAVEESFLE EEHHGRATEK EVADWVRRVR AEAAKLAARR
EAKARWDEGR VGGWR
//
