ID A1DHG4_NEOFI Unreviewed; 430 AA.
AC A1DHG4;
DT 23-JAN-2007, integrated into UniProtKB/TrEMBL.
DT 23-JAN-2007, sequence version 1.
DT 27-MAR-2024, entry version 63.
DE RecName: Full=G protein-coupled receptor GPR1 C-terminal domain-containing protein {ECO:0000259|Pfam:PF11970};
GN ORFNames=NFIA_087770 {ECO:0000313|EMBL:EAW18821.1};
OS Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164
OS / JCM 1740 / NRRL 181 / WB 181) (Aspergillus fischerianus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Fumigati.
OX NCBI_TaxID=331117 {ECO:0000313|EMBL:EAW18821.1, ECO:0000313|Proteomes:UP000006702};
RN [1] {ECO:0000313|Proteomes:UP000006702}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 /
RC NRRL 181 / WB 181 {ECO:0000313|Proteomes:UP000006702};
RX PubMed=18404212; DOI=10.1371/journal.pgen.1000046;
RA Fedorova N.D., Khaldi N., Joardar V.S., Maiti R., Amedeo P., Anderson M.J.,
RA Crabtree J., Silva J.C., Badger J.H., Albarraq A., Angiuoli S., Bussey H.,
RA Bowyer P., Cotty P.J., Dyer P.S., Egan A., Galens K., Fraser-Liggett C.M.,
RA Haas B.J., Inman J.M., Kent R., Lemieux S., Malavazi I., Orvis J.,
RA Roemer T., Ronning C.M., Sundaram J.P., Sutton G., Turner G., Venter J.C.,
RA White O.R., Whitty B.R., Youngman P., Wolfe K.H., Goldman G.H.,
RA Wortman J.R., Jiang B., Denning D.W., Nierman W.C.;
RT "Genomic islands in the pathogenic filamentous fungus Aspergillus
RT fumigatus.";
RL PLoS Genet. 4:E1000046-E1000046(2008).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; DS027696; EAW18821.1; -; Genomic_DNA.
DR RefSeq; XP_001260718.1; XM_001260717.1.
DR AlphaFoldDB; A1DHG4; -.
DR STRING; 331117.A1DHG4; -.
DR EnsemblFungi; EAW18821; EAW18821; NFIA_087770.
DR GeneID; 4587276; -.
DR KEGG; nfi:NFIA_087770; -.
DR VEuPathDB; FungiDB:NFIA_087770; -.
DR eggNOG; ENOG502RYZC; Eukaryota.
DR HOGENOM; CLU_027149_3_1_1; -.
DR OMA; FLISFHW; -.
DR OrthoDB; 2682754at2759; -.
DR Proteomes; UP000006702; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0007165; P:signal transduction; IEA:UniProt.
DR CDD; cd00637; 7tm_classA_rhodopsin-like; 1.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR InterPro; IPR022596; GPR1_C.
DR PANTHER; PTHR23112; G PROTEIN-COUPLED RECEPTOR 157-RELATED; 1.
DR PANTHER; PTHR23112:SF41; INTEGRAL MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_2G12640); 1.
DR Pfam; PF11970; GPR_Gpa2_C; 1.
DR SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000006702};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 46..69
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 90..113
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 138..156
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 163..186
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 214..235
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 256..279
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 294..315
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 252..319
FT /note="G protein-coupled receptor GPR1 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF11970"
FT REGION 376..396
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 376..390
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 430 AA; 48482 MW; E17295307E010084 CRC64;
MTSLVRTLLL LRSENGDKPY LTARSQEVQP PTFADEPLTG SLRAGFIAIG AVALCSWIAT
FSLISFLTYR FIFWQRYYKR PLAHNQYVFL IYNLLLVDIQ QATAFLLCLH WVARGGVNYP
SAACVLQGWW IQTADPGSGL FVLAIAIHTC VVVLRGRQLP FTTFVWCVVG LWAFIILLGL
IAVGLYGSKT FVISEAGWCW LSPQAQDERL WGHYVWIFLS EFGTIVLYGI MFFYLRRRMK
QAAALRQNHQ ESLNRLNRVV VYMVIYPLVY VLLSLPLAAG RMSTARHVVP SKEYFAAAGA
LMALSGLVDV IVYTLTRRHL LLDTEVSTSD RYYAHTGSNL YNTHVSTTVA GPESKKSRVK
SRLRRGLQSI NDTVLDDRGD STEDIVPKGP KGDMELSNMA HGVYQETTIE ITHEAAEPEE
ALRKPNRFSR
//
