ID A1HN79_9FIRM Unreviewed; 1185 AA.
AC A1HN79;
DT 06-FEB-2007, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2007, sequence version 1.
DT 24-JAN-2024, entry version 74.
DE RecName: Full=Chromosome partition protein Smc {ECO:0000256|HAMAP-Rule:MF_01894};
GN Name=smc {ECO:0000256|HAMAP-Rule:MF_01894};
GN ORFNames=TcarDRAFT_2177 {ECO:0000313|EMBL:EAX48705.1};
OS Thermosinus carboxydivorans Nor1.
OC Bacteria; Bacillota; Negativicutes; Selenomonadales; Sporomusaceae;
OC Thermosinus.
OX NCBI_TaxID=401526 {ECO:0000313|EMBL:EAX48705.1, ECO:0000313|Proteomes:UP000005139};
RN [1] {ECO:0000313|EMBL:EAX48705.1, ECO:0000313|Proteomes:UP000005139}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Nor1 {ECO:0000313|EMBL:EAX48705.1,
RC ECO:0000313|Proteomes:UP000005139};
RG US DOE Joint Genome Institute (JGI-ORNL);
RA Larimer F., Land M., Hauser L.;
RT "Annotation of the draft genome assembly of Thermosinus carboxydivorans
RT Nor1.";
RL Submitted (JAN-2007) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EAX48705.1, ECO:0000313|Proteomes:UP000005139}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Nor1 {ECO:0000313|EMBL:EAX48705.1,
RC ECO:0000313|Proteomes:UP000005139};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E.,
RA Tice H., Bruce D., Pitluck S., Richardson P.;
RT "Sequencing of the draft genome and assembly of Thermosinus carboxydivorans
RT Nor1.";
RL Submitted (JAN-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for chromosome condensation and partitioning.
CC {ECO:0000256|HAMAP-Rule:MF_01894}.
CC -!- SUBUNIT: Homodimer. {ECO:0000256|HAMAP-Rule:MF_01894}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_01894}.
CC -!- DOMAIN: Contains large globular domains required for ATP hydrolysis at
CC each terminus and a third globular domain forming a flexible hinge near
CC the middle of the molecule. These domains are separated by coiled-coil
CC structures. {ECO:0000256|HAMAP-Rule:MF_01894}.
CC -!- SIMILARITY: Belongs to the SMC family. SMC3 subfamily.
CC {ECO:0000256|ARBA:ARBA00005917}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EAX48705.1}.
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DR EMBL; AAWL01000002; EAX48705.1; -; Genomic_DNA.
DR RefSeq; WP_007288476.1; NZ_AAWL01000002.1.
DR AlphaFoldDB; A1HN79; -.
DR eggNOG; COG1196; Bacteria.
DR OrthoDB; 9808768at2; -.
DR Proteomes; UP000005139; Unassembled WGS sequence.
DR GO; GO:0005694; C:chromosome; IEA:InterPro.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0030261; P:chromosome condensation; IEA:InterPro.
DR GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-UniRule.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR GO; GO:0007062; P:sister chromatid cohesion; IEA:InterPro.
DR CDD; cd03278; ABC_SMC_barmotin; 2.
DR Gene3D; 1.10.287.1490; -; 1.
DR Gene3D; 1.20.1060.20; -; 1.
DR Gene3D; 3.30.70.1620; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR HAMAP; MF_01894; Smc_prok; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR003395; RecF/RecN/SMC_N.
DR InterPro; IPR024704; SMC.
DR InterPro; IPR010935; SMC_hinge.
DR InterPro; IPR036277; SMC_hinge_sf.
DR InterPro; IPR011890; SMC_prok.
DR NCBIfam; TIGR02168; SMC_prok_B; 1.
DR PANTHER; PTHR43977; STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 3; 1.
DR PANTHER; PTHR43977:SF1; STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 3; 1.
DR Pfam; PF06470; SMC_hinge; 1.
DR Pfam; PF02463; SMC_N; 1.
DR PIRSF; PIRSF005719; SMC; 1.
DR SMART; SM00968; SMC_hinge; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF75553; Smc hinge domain; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|HAMAP-Rule:MF_01894};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|HAMAP-
KW Rule:MF_01894};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490, ECO:0000256|HAMAP-Rule:MF_01894};
KW DNA-binding {ECO:0000256|HAMAP-Rule:MF_01894};
KW Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_01894};
KW Reference proteome {ECO:0000313|Proteomes:UP000005139}.
FT DOMAIN 522..640
FT /note="SMC hinge"
FT /evidence="ECO:0000259|SMART:SM00968"
FT COILED 167..201
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01894"
FT COILED 234..310
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01894"
FT COILED 346..450
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01894"
FT COILED 682..856
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01894"
FT COILED 899..933
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01894"
FT BINDING 32..39
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01894"
SQ SEQUENCE 1185 AA; 133747 MW; 45687B915C3AE19B CRC64;
MLLRKLELYG FKSFADKTEV EFGPGITAIV GPNGSGKSNI TDAIRWALGE QNIRNLRGAK
VEDVIFAGSA KRRPLGVAEV SLVFDNSSGT LPLDFNEVTI TRRVYRSGDS EYYINKAPCR
LKDIHELLFD VGIGRDSLTV IGQNKIDEVL NAKAEERRLF FEEAAGITKY KHRKREALRK
LEETEQNLVR VNDLIAEIHN QLGPLAESAE RTKRYNVLRQ ELISCQVTVL LDRLERATKM
AESARLEQET LTEQEVVAAA QLSVRESEKE RLTDEINRYS EQQSILDQQI SQAATELERI
DGKLAVLRER IEQGHRSGER VAREITRLED TAQGLDAKIT FLKSTLAAKE TQLAAAKETL
AASNTNYEKL VMDIHQAEQE LEQGKAQTFV HIQQLVDERN KLRLMERDLA KLVARRDSLA
AERQNYLAQL TKAEEQRQNL TAERDWLIQQ IGSAKDRISV LTSEKEKWEQ HLQDFVRIQH
NLQAERDELR SRLKILTGMQ QDYEGFSRGI KSLLKTDAPW RRYIHGAVAE VIGVARPYLT
AIEVALGGAL QYIITDNDET AKQAIAFLKT HNLGRATFLP LNTVRPSLPR PAEIAAAKAR
GAIGLAASLV DCAPIYRPVI DFLLGHTVVV ETLDAAVKIA KEQSFTVRLV TLDGQQVNPG
GTLTGGSTAK KENSFLGRSH EIEKLKERLA EMDQRLAAQQ AQAVAARTEV ERLAAEIAAV
QREMQGKEVR LAEVAVHFDT VRADAARLRL ALQTIEQEME TNEAEQQELA QSVKNLENGI
ALMESRDSQQ KETMVRLQQE LKKLQEQKEE LLAELAERRV QLATLEQDIH TGQANCLQYE
QDKGALDRQL QNLRDEQVHI ADQIARAGAE IDALTVARLK RSTEKCEWER QRQETVQTKV
NLLAELQRVD KDIRELRRKH QELRNRLHDV SLIAAKYNYE IAHCQEQLRD SCSLSVEEAA
MLRRNDPPEV LEGLIRRLEM EIAAIGPVNP AAVEEYNRLN QRYNFYQSQS QDLIAAKEYL
TSVINQIDDT MAKQFKTAFS AINRYFGEIF TRLFGGGKAE LVLQQPDDIL NTGIDVIAQP
PGKKLQNLAL LSGGERALTV IALLFAFLTY RPSPFCVVDE IDAALDEANV QRFSEFLRDY
KGKTQFIVVT HRKGTMEFAD IMQGVTMEES GVSRLVSVKF MDKAG
//
