ID A1K4D2_AZOSB Unreviewed; 296 AA.
AC A1K4D2;
DT 06-FEB-2007, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2007, sequence version 1.
DT 27-MAR-2024, entry version 80.
DE SubName: Full=Probable prephenate dehydrogenase {ECO:0000313|EMBL:CAL93687.1};
DE EC=1.3.1.12 {ECO:0000313|EMBL:CAL93687.1};
GN Name=tyrA {ECO:0000313|EMBL:CAL93687.1};
GN OrderedLocusNames=azo1070 {ECO:0000313|EMBL:CAL93687.1};
OS Azoarcus sp. (strain BH72).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales; Zoogloeaceae;
OC Azoarcus.
OX NCBI_TaxID=418699 {ECO:0000313|EMBL:CAL93687.1, ECO:0000313|Proteomes:UP000002588};
RN [1] {ECO:0000313|EMBL:CAL93687.1, ECO:0000313|Proteomes:UP000002588}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BH72 {ECO:0000313|EMBL:CAL93687.1,
RC ECO:0000313|Proteomes:UP000002588};
RX PubMed=17057704; DOI=10.1038/nbt1243;
RA Krause A., Ramakumar A., Bartels D., Battistoni F., Bekel T., Boch J.,
RA Boehm M., Friedrich F., Hurek T., Krause L., Linke B., McHardy A.C.,
RA Sarkar A., Schneiker S., Syed A.A., Thauer R., Vorhoelter F.-J.,
RA Weidner S., Puehler A., Reinhold-Hurek B., Kaiser O., Goesmann A.;
RT "Complete genome of the mutualistic, N2-fixing grass endophyte Azoarcus sp.
RT strain BH72.";
RL Nat. Biotechnol. 24:1385-1391(2006).
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DR EMBL; AM406670; CAL93687.1; -; Genomic_DNA.
DR RefSeq; WP_011764804.1; NC_008702.1.
DR AlphaFoldDB; A1K4D2; -.
DR STRING; 62928.azo1070; -.
DR KEGG; azo:azo1070; -.
DR eggNOG; COG0287; Bacteria.
DR HOGENOM; CLU_055968_0_1_4; -.
DR Proteomes; UP000002588; Chromosome.
DR GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR GO; GO:0008977; F:prephenate dehydrogenase (NAD+) activity; IEA:UniProtKB-EC.
DR GO; GO:0004665; F:prephenate dehydrogenase (NADP+) activity; IEA:InterPro.
DR GO; GO:0006571; P:tyrosine biosynthetic process; IEA:InterPro.
DR Gene3D; 1.10.3660.10; 6-phosphogluconate dehydrogenase C-terminal like domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR046825; PDH_C.
DR InterPro; IPR046826; PDH_N.
DR InterPro; IPR003099; Prephen_DH.
DR PANTHER; PTHR21363; PREPHENATE DEHYDROGENASE; 1.
DR PANTHER; PTHR21363:SF0; PREPHENATE DEHYDROGENASE [NADP(+)]; 1.
DR Pfam; PF20463; PDH_C; 1.
DR Pfam; PF02153; PDH_N; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS51176; PDH_ADH; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:CAL93687.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000002588}.
FT DOMAIN 5..293
FT /note="Prephenate/arogenate dehydrogenase"
FT /evidence="ECO:0000259|PROSITE:PS51176"
SQ SEQUENCE 296 AA; 31480 MW; DE4EAD9F95D6C066 CRC64;
MALIGKLVVC GVGLIGGSFA LALKQAGAVE RVVGVGRNPA TLARAVELGV IDEIAAGWRD
ALDGADFVLL ATPVGQLDAI MEAMAPHLQP GTIVTDAGST KRDVIEAVYR RLDPHLATVV
PAHPIAGAEK SGVEAGFPTL YRGKKVVVTP LPENRPDAVE RVRAAWTACG ATVVEMSPQD
HDRVFAAVSH LPHLLAFGLV HDLAGRANAE LLFSHAASGF RDFTRIAGSH PEMWRDICLA
NRQALLAELD QYLAELAYLR ALLLAGDGTR LEQLFGEARR ARDAWAAQFP PPSTAE
//
