ID A1KC83_AZOSB Unreviewed; 252 AA.
AC A1KC83;
DT 06-FEB-2007, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2007, sequence version 1.
DT 27-MAR-2024, entry version 71.
DE RecName: Full=Metallo-beta-lactamase domain-containing protein {ECO:0000259|SMART:SM00849};
GN Name=ycbL {ECO:0000313|EMBL:CAL96439.1};
GN OrderedLocusNames=azo3823 {ECO:0000313|EMBL:CAL96439.1};
OS Azoarcus sp. (strain BH72).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Rhodocyclales; Zoogloeaceae;
OC Azoarcus.
OX NCBI_TaxID=418699 {ECO:0000313|EMBL:CAL96439.1, ECO:0000313|Proteomes:UP000002588};
RN [1] {ECO:0000313|EMBL:CAL96439.1, ECO:0000313|Proteomes:UP000002588}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BH72 {ECO:0000313|EMBL:CAL96439.1,
RC ECO:0000313|Proteomes:UP000002588};
RX PubMed=17057704; DOI=10.1038/nbt1243;
RA Krause A., Ramakumar A., Bartels D., Battistoni F., Bekel T., Boch J.,
RA Boehm M., Friedrich F., Hurek T., Krause L., Linke B., McHardy A.C.,
RA Sarkar A., Schneiker S., Syed A.A., Thauer R., Vorhoelter F.-J.,
RA Weidner S., Puehler A., Reinhold-Hurek B., Kaiser O., Goesmann A.;
RT "Complete genome of the mutualistic, N2-fixing grass endophyte Azoarcus sp.
RT strain BH72.";
RL Nat. Biotechnol. 24:1385-1391(2006).
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
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DR EMBL; AM406670; CAL96439.1; -; Genomic_DNA.
DR AlphaFoldDB; A1KC83; -.
DR STRING; 62928.azo3823; -.
DR KEGG; azo:azo3823; -.
DR eggNOG; COG0491; Bacteria.
DR HOGENOM; CLU_030571_5_0_4; -.
DR Proteomes; UP000002588; Chromosome.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd07737; YcbL-like_MBL-fold; 1.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR PANTHER; PTHR46233; HYDROXYACYLGLUTATHIONE HYDROLASE GLOC; 1.
DR PANTHER; PTHR46233:SF3; HYDROXYACYLGLUTATHIONE HYDROLASE GLOC; 1.
DR Pfam; PF00753; Lactamase_B; 1.
DR SMART; SM00849; Lactamase_B; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:CAL96439.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000002588};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..252
FT /note="Metallo-beta-lactamase domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002635452"
FT DOMAIN 52..232
FT /note="Metallo-beta-lactamase"
FT /evidence="ECO:0000259|SMART:SM00849"
FT REGION 233..252
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 252 AA; 27007 MW; 53646CBDD4719CD6 CRC64;
MSALARAAVR ICFQAARGLA MAVRASVTLP AAFSAEPAAM LQIQIVPVTA FEQNCSILWC
DRSMKAAVVD PGGDLERIHA AVKKLGVSVE KILITHGHID HAGGTARLAR DLGVPVEGPQ
QEDRFWIVAM PQQSKMFGFP DVEAFEPDRW LGDGDTVSVG EETLQVIHAP GHTPGHVVFF
QPEARLAVVG DVLFAGSIGR TDFPRGNHAE LISSIRNKLF PLGDDVTFIP GHGPASTFGD
ERDSNPYVGD HA
//
