ID ZB8AB_XENLA Reviewed; 469 AA.
AC A1L2U9;
DT 07-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT 06-FEB-2007, sequence version 1.
DT 27-MAR-2024, entry version 72.
DE RecName: Full=Zinc finger and BTB domain-containing protein 8A.1-B;
GN Name=zbtb8a.1-b;
OS Xenopus laevis (African clawed frog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX NCBI_TaxID=8355;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Thymus;
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: May be involved in transcriptional regulation.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
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DR EMBL; BC129718; AAI29719.1; -; mRNA.
DR RefSeq; NP_001091193.1; NM_001097724.1.
DR AlphaFoldDB; A1L2U9; -.
DR SMR; A1L2U9; -.
DR DNASU; 100036960; -.
DR GeneID; 100036960; -.
DR KEGG; xla:100036960; -.
DR AGR; Xenbase:XB-GENE-6255849; -.
DR CTD; 100036960; -.
DR Xenbase; XB-GENE-6255849; zbtb8a.1.S.
DR OrthoDB; 5343486at2759; -.
DR Proteomes; UP000186698; Chromosome 2S.
DR Bgee; 100036960; Expressed in oocyte and 19 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd18329; BTB_POZ_ZBTB8A_BOZF1; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 2.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR46105; AGAP004733-PA; 1.
DR PANTHER; PTHR46105:SF12; ZINC FINGER AND BTB DOMAIN-CONTAINING PROTEIN 8A; 1.
DR Pfam; PF00651; BTB; 1.
DR Pfam; PF00096; zf-C2H2; 1.
DR SMART; SM00225; BTB; 1.
DR SMART; SM00355; ZnF_C2H2; 2.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 1.
DR SUPFAM; SSF54695; POZ domain; 1.
DR PROSITE; PS50097; BTB; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 2.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 2.
PE 2: Evidence at transcript level;
KW DNA-binding; Metal-binding; Nucleus; Phosphoprotein; Reference proteome;
KW Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger.
FT CHAIN 1..469
FT /note="Zinc finger and BTB domain-containing protein 8A.1-
FT B"
FT /id="PRO_0000378512"
FT DOMAIN 24..92
FT /note="BTB"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00037"
FT ZN_FING 315..337
FT /note="C2H2-type 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT ZN_FING 343..366
FT /note="C2H2-type 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
SQ SEQUENCE 469 AA; 52998 MW; BA2B6D07F4AAB559 CRC64;
MEFSSHHIRL LQQLDEQRRR DLFCDCHIIV EGQMFKAHRN VLFASSGYFK MLLSQSCRDM
GEPITATFDV FSADTFTAIL DFVYSGKLPL SGQNVIEVMS AASYLQMTDV IGVCKMFIKS
SLDINEKDRD GFFSLSDKDT DSNGSGLYAA GWRTESSPTH THKTTEHGSF IAGYNYPPPI
SSRLQHPFSK SPRKPELVRK HRRRLLPEAL TPALSHIPLG DLVGGSTECM LHDEETVESV
SQEEERTQTQ VSIISIKVED LDATSNSWPE SPPQESLDQG SALHITKAEE LYKAMPTILG
GVSGWGEDEL SSGRFKCPFC THTVKRKADL KRHLRCHTGE RPYPCEACGK RFTRLEHLRN
HFQTIHEAGK LICRRCKLPV TKVTGRVIQD GTRRYRLCQA CLAEAGLDNV NFDYGEDQPL
VLPPENEREH CWNFKEEGRQ ENGSEAAESD LVIQEVVDSE EDELKQKQD
//
