ID   A1R634_PAEAT            Unreviewed;       342 AA.
AC   A1R634;
DT   06-FEB-2007, integrated into UniProtKB/TrEMBL.
DT   06-FEB-2007, sequence version 1.
DT   27-MAR-2024, entry version 97.
DE   RecName: Full=D-lactate dehydratase {ECO:0000256|ARBA:ARBA00013134};
DE            EC=4.2.1.130 {ECO:0000256|ARBA:ARBA00013134};
GN   OrderedLocusNames=AAur_1951 {ECO:0000313|EMBL:ABM06446.1};
OS   Paenarthrobacter aurescens (strain TC1).
OC   Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Micrococcaceae;
OC   Paenarthrobacter.
OX   NCBI_TaxID=290340 {ECO:0000313|EMBL:ABM06446.1, ECO:0000313|Proteomes:UP000000637};
RN   [1] {ECO:0000313|EMBL:ABM06446.1, ECO:0000313|Proteomes:UP000000637}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TC1 {ECO:0000313|EMBL:ABM06446.1,
RC   ECO:0000313|Proteomes:UP000000637};
RX   PubMed=17194220; DOI=10.1371/journal.pgen.0020214;
RA   Mongodin E.F., Shapir N., Daugherty S.C., DeBoy R.T., Emerson J.B.,
RA   Shvartzbeyn A., Radune D., Vamathevan J., Riggs F., Grinberg V., Khouri H.,
RA   Wackett L.P., Nelson K.E., Sadowsky M.J.;
RT   "Secrets of soil survival revealed by the genome sequence of Arthrobacter
RT   aurescens TC1.";
RL   PLoS Genet. 2:2094-2106(2006).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=H2O + methylglyoxal = (R)-lactate + H(+);
CC         Xref=Rhea:RHEA:27754, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:16004, ChEBI:CHEBI:17158; EC=4.2.1.130;
CC         Evidence={ECO:0000256|ARBA:ARBA00001524};
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DR   EMBL; CP000474; ABM06446.1; -; Genomic_DNA.
DR   AlphaFoldDB; A1R634; -.
DR   STRING; 290340.AAur_1951; -.
DR   KEGG; aau:AAur_1951; -.
DR   eggNOG; COG0693; Bacteria.
DR   HOGENOM; CLU_810497_0_0_11; -.
DR   OrthoDB; 9792284at2; -.
DR   Proteomes; UP000000637; Chromosome.
DR   CDD; cd03141; GATase1_Hsp31_like; 1.
DR   Gene3D; 3.40.50.880; -; 1.
DR   InterPro; IPR029062; Class_I_gatase-like.
DR   InterPro; IPR002818; DJ-1/PfpI.
DR   PANTHER; PTHR48094:SF11; GLUTATHIONE-INDEPENDENT GLYOXALASE HSP31-RELATED; 1.
DR   PANTHER; PTHR48094; PROTEIN/NUCLEIC ACID DEGLYCASE DJ-1-RELATED; 1.
DR   Pfam; PF01965; DJ-1_PfpI; 1.
DR   SUPFAM; SSF52317; Class I glutamine amidotransferase-like; 1.
PE   4: Predicted;
KW   Stress response {ECO:0000256|ARBA:ARBA00023016}.
FT   DOMAIN          109..299
FT                   /note="DJ-1/PfpI"
FT                   /evidence="ECO:0000259|Pfam:PF01965"
FT   REGION          315..342
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   342 AA;  37255 MW;  7E0BA1BD7BD7C217 CRC64;
     MNLFRDLAFN VSRYRRVLLF ISRHEPSIGA HADELGKAEP FSNSGQWVQS ARVVRGSEGL
     RSSSLPEGLK RVGRSVDVGR KEHFMKKILM VLTSVSELGD TGEKTGYNVA EAAHPWKVFK
     DSGHFVDFAS IKGGQPPSDE VDTDDPIQVA FTTDETTRAG LYNTARVDVI DPGQYDAVYL
     VGGHGTMWDF PDSEGLQRLV ASVYDAGGLV GAVCHGPAGL LNVELENGFR LVQGRDVAAF
     TNEEEVAAGK DKVIPFFLAD RLEEQGARHV TAGVFEEKVA VDDRLVTGQN PASAAGVAKE
     MEKLFAQVIH QEKAEEQHEA EALRAEKDAE KTAKKHAAEA EH
//