ID A1R6H7_PAEAT Unreviewed; 543 AA.
AC A1R6H7;
DT 06-FEB-2007, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2007, sequence version 1.
DT 27-MAR-2024, entry version 120.
DE RecName: Full=Glucose-6-phosphate isomerase {ECO:0000256|RuleBase:RU000612};
DE EC=5.3.1.9 {ECO:0000256|RuleBase:RU000612};
GN Name=pgi {ECO:0000313|EMBL:ABM08410.1};
GN OrderedLocusNames=AAur_2095 {ECO:0000313|EMBL:ABM08410.1};
OS Paenarthrobacter aurescens (strain TC1).
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Micrococcaceae;
OC Paenarthrobacter.
OX NCBI_TaxID=290340 {ECO:0000313|EMBL:ABM08410.1, ECO:0000313|Proteomes:UP000000637};
RN [1] {ECO:0000313|EMBL:ABM08410.1, ECO:0000313|Proteomes:UP000000637}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TC1 {ECO:0000313|EMBL:ABM08410.1,
RC ECO:0000313|Proteomes:UP000000637};
RX PubMed=17194220; DOI=10.1371/journal.pgen.0020214;
RA Mongodin E.F., Shapir N., Daugherty S.C., DeBoy R.T., Emerson J.B.,
RA Shvartzbeyn A., Radune D., Vamathevan J., Riggs F., Grinberg V., Khouri H.,
RA Wackett L.P., Nelson K.E., Sadowsky M.J.;
RT "Secrets of soil survival revealed by the genome sequence of Arthrobacter
RT aurescens TC1.";
RL PLoS Genet. 2:2094-2106(2006).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate;
CC Xref=Rhea:RHEA:11816, ChEBI:CHEBI:57634, ChEBI:CHEBI:58225;
CC EC=5.3.1.9; Evidence={ECO:0000256|RuleBase:RU000612};
CC -!- PATHWAY: Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-
CC phosphate and glycerone phosphate from D-glucose: step 2/4.
CC {ECO:0000256|RuleBase:RU000612}.
CC -!- SIMILARITY: Belongs to the GPI family. {ECO:0000256|RuleBase:RU000612}.
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DR EMBL; CP000474; ABM08410.1; -; Genomic_DNA.
DR RefSeq; WP_011774783.1; NC_008711.1.
DR AlphaFoldDB; A1R6H7; -.
DR SMR; A1R6H7; -.
DR STRING; 290340.AAur_2095; -.
DR KEGG; aau:AAur_2095; -.
DR eggNOG; COG0166; Bacteria.
DR HOGENOM; CLU_036298_0_0_11; -.
DR OrthoDB; 140919at2; -.
DR UniPathway; UPA00109; UER00181.
DR Proteomes; UP000000637; Chromosome.
DR GO; GO:0097367; F:carbohydrate derivative binding; IEA:InterPro.
DR GO; GO:0004347; F:glucose-6-phosphate isomerase activity; IEA:UniProtKB-EC.
DR GO; GO:0006094; P:gluconeogenesis; IEA:UniProtKB-KW.
DR GO; GO:0006096; P:glycolytic process; IEA:UniProtKB-UniPathway.
DR InterPro; IPR001672; G6P_Isomerase.
DR InterPro; IPR046348; SIS_dom_sf.
DR PANTHER; PTHR11469; GLUCOSE-6-PHOSPHATE ISOMERASE; 1.
DR PANTHER; PTHR11469:SF1; GLUCOSE-6-PHOSPHATE ISOMERASE; 1.
DR Pfam; PF00342; PGI; 1.
DR PRINTS; PR00662; G6PISOMERASE.
DR SUPFAM; SSF53697; SIS domain; 1.
DR PROSITE; PS51463; P_GLUCOSE_ISOMERASE_3; 2.
PE 3: Inferred from homology;
KW Gluconeogenesis {ECO:0000256|ARBA:ARBA00022432,
KW ECO:0000256|RuleBase:RU000612};
KW Glycolysis {ECO:0000256|ARBA:ARBA00023152, ECO:0000256|RuleBase:RU000612};
KW Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000256|RuleBase:RU000612}.
SQ SEQUENCE 543 AA; 56272 MW; 47A703B14757EB54 CRC64;
MSTISYDASG AAQEAIAQHI DSLVEDKIAT RIFAKDHTLW GPDAESESAI RLGWVEAATV
SQALVGDILE LRDALRADGV SRIVLCGMGG SSLAPEVIAG TAGVELTVLD STDPEQVSAA
LADRLEETAI VVSSKSGSTV ETDSQRRVFE KAFNDAGIDA KSRIIIVTDP GSPLDKASRE
AGYRAVFNAD PNVGGRFSAL TAFGLVPSGL AGVDIQAFLD EAEEAAEILN EDSADNIGLA
LGIALGGTSP LRNKIVIAED GSGIVGFADW AEQLIAESTG KLGTGVLPVV AGPDSPEATN
GADDVLVVRL VGADADVELR ENEVAIAGGL PSQMFVWEFA TAVAGRLLGI NPYDQPDVEA
AKVAARGLLD ARPEPTPAVF TDGAVEVRGG DWLGSASTVS EAVQALLAQL GADGYLSVQA
YFDRISYAPL EGIRDELAAV SGRPVTFGWG PRFLHSTGQF HKGGPAIGVF LQITAASSTD
LDIPERPFTF GQLIAAQASG DAQVLEGHGR PVLRLHLTER AAGVAQLQEV VAALTTQASA
LES
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