ID A1S011_THEPD Unreviewed; 559 AA.
AC A1S011;
DT 06-FEB-2007, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2007, sequence version 1.
DT 27-MAR-2024, entry version 78.
DE RecName: Full=Helicase HerA central domain-containing protein {ECO:0000259|Pfam:PF01935};
GN OrderedLocusNames=Tpen_1394 {ECO:0000313|EMBL:ABL78791.1};
OS Thermofilum pendens (strain DSM 2475 / Hrk 5).
OC Archaea; Thermoproteota; Thermoprotei; Thermofilales; Thermofilaceae;
OC Thermofilum.
OX NCBI_TaxID=368408 {ECO:0000313|EMBL:ABL78791.1, ECO:0000313|Proteomes:UP000000641};
RN [1] {ECO:0000313|Proteomes:UP000000641}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 2475 / Hrk 5 {ECO:0000313|Proteomes:UP000000641};
RX PubMed=18263724; DOI=10.1128/JB.01949-07;
RA Anderson I., Rodriguez J., Susanti D., Porat I., Reich C., Ulrich L.E.,
RA Elkins J.G., Mavromatis K., Lykidis A., Kim E., Thompson L.S., Nolan M.,
RA Land M., Copeland A., Lapidus A., Lucas S., Detter C., Zhulin I.B.,
RA Olsen G.J., Whitman W., Mukhopadhyay B., Bristow J., Kyrpides N.;
RT "Genome sequence of Thermofilum pendens reveals an exceptional loss of
RT biosynthetic pathways without genome reduction.";
RL J. Bacteriol. 190:2957-2965(2008).
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DR EMBL; CP000505; ABL78791.1; -; Genomic_DNA.
DR AlphaFoldDB; A1S011; -.
DR STRING; 368408.Tpen_1394; -.
DR EnsemblBacteria; ABL78791; ABL78791; Tpen_1394.
DR KEGG; tpe:Tpen_1394; -.
DR eggNOG; arCOG00280; Archaea.
DR HOGENOM; CLU_023842_1_0_2; -.
DR OrthoDB; 107033at2157; -.
DR Proteomes; UP000000641; Chromosome.
DR CDD; cd01127; TrwB_TraG_TraD_VirD4; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR002789; HerA_central.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR42957; HELICASE MJ1565-RELATED; 1.
DR PANTHER; PTHR42957:SF1; HELICASE MJ1565-RELATED; 1.
DR Pfam; PF01935; DUF87; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000000641}.
FT DOMAIN 123..308
FT /note="Helicase HerA central"
FT /evidence="ECO:0000259|Pfam:PF01935"
FT REGION 540..559
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 545..559
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 559 AA; 62096 MW; 5B8CDC707216CC2D CRC64;
MEVGRVVTVY GQSLLRFAVH EDKLGYLARP GAYVKVEASG GWSYAMVVSF NLLDELYRKS
RIVEELEGYP EIRPSRNELV AMLVGYYDGK GFVRGVPELP RPGQKVYLAD GEELARFVGS
GDIAIGRLSQ NPEVRYTLSL DMLCSRHFAV LAMTGAGKSN AVAVILGEIL EKFPYSRVVV
VDTHNEYVPL AEKFDRVRVL SPAGRIARLV EARYGVKPSP LEVPIWTLGL EEIAGLLRLD
PTRATKQVMY LRGALQEVRR ARYKYAGADD PIYFRAEELL GYLEGLQKSS RQRYDRSLDD
LVLKLEMLLE NSELRYVTRP RNSDRLYEGL GGEEPRRSVE AYMRVYGALL EPGVTLIALG
GLASDAQVST AATILKSLWR IITASVLAGK PQPTLLVVEE AHNYAPQGRW SPAREILEKI
AKEGRKFGIG LGVVSQRPRE LSQTLLAQCG TLIALRTANP RDQEYILGSM EDVMREMVEG
LSGLVTGEAL ISGSAAPLPG IVRIDSFPER YGVNLGGKDI DWRAAWSTPQ PKADLAEYVL
GEPEEEEEER KTSTIDKFL
//
