ID A1SI94_NOCSJ Unreviewed; 841 AA.
AC A1SI94;
DT 06-FEB-2007, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2007, sequence version 1.
DT 27-MAR-2024, entry version 84.
DE SubName: Full=AMP-dependent synthetase and ligase {ECO:0000313|EMBL:ABL81529.1};
GN OrderedLocusNames=Noca_2019 {ECO:0000313|EMBL:ABL81529.1};
OS Nocardioides sp. (strain ATCC BAA-499 / JS614).
OC Bacteria; Actinomycetota; Actinomycetes; Propionibacteriales;
OC Nocardioidaceae; Nocardioides.
OX NCBI_TaxID=196162 {ECO:0000313|EMBL:ABL81529.1, ECO:0000313|Proteomes:UP000000640};
RN [1] {ECO:0000313|Proteomes:UP000000640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-499 / JS614 {ECO:0000313|Proteomes:UP000000640};
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA Thompson L.S., Brettin T., Bruce D., Han C., Tapia R., Schmutz J.,
RA Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Mattes T., Gossett J.,
RA Richardson P.;
RT "Complete sequence of chromosome 1 of Nocardioides sp. JS614.";
RL Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ABL81529.1, ECO:0000313|Proteomes:UP000000640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-499 / JS614 {ECO:0000313|Proteomes:UP000000640};
RX PubMed=21551312; DOI=10.1128/JB.05109-11;
RA Coleman N.V., Wilson N.L., Barry K., Brettin T.S., Bruce D.C., Copeland A.,
RA Dalin E., Detter J.C., Del Rio T.G., Goodwin L.A., Hammon N.M., Han S.,
RA Hauser L.J., Israni S., Kim E., Kyrpides N., Land M.L., Lapidus A.,
RA Larimer F.W., Lucas S., Pitluck S., Richardson P., Schmutz J., Tapia R.,
RA Thompson S., Tice H.N., Spain J.C., Gossett J.G., Mattes T.E.;
RT "Genome Sequence of the ethene- and vinyl chloride-oxidizing actinomycete
RT Nocardioides sp. strain JS614.";
RL J. Bacteriol. 193:3399-3400(2011).
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DR EMBL; CP000509; ABL81529.1; -; Genomic_DNA.
DR RefSeq; WP_011755476.1; NC_008699.1.
DR AlphaFoldDB; A1SI94; -.
DR STRING; 196162.Noca_2019; -.
DR KEGG; nca:Noca_2019; -.
DR eggNOG; COG0318; Bacteria.
DR HOGENOM; CLU_337954_0_0_11; -.
DR Proteomes; UP000000640; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR Gene3D; 1.10.1200.10; ACP-like; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 2.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR002656; Acyl_transf_3_dom.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR006162; Ppantetheine_attach_site.
DR PANTHER; PTHR43767; LONG-CHAIN-FATTY-ACID--COA LIGASE; 1.
DR PANTHER; PTHR43767:SF10; SURFACTIN SYNTHASE SUBUNIT 1; 1.
DR Pfam; PF01757; Acyl_transf_3; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF00550; PP-binding; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR SUPFAM; SSF47336; ACP-like; 1.
DR PROSITE; PS00012; PHOSPHOPANTETHEINE; 1.
PE 4: Predicted;
KW Ligase {ECO:0000313|EMBL:ABL81529.1}; Membrane {ECO:0000256|SAM:Phobius};
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000000640};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 569..588
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 600..621
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 646..667
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 679..701
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 707..725
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 732..748
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 754..770
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 777..796
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 808..827
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 106..325
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 475..516
FT /note="Carrier"
FT /evidence="ECO:0000259|Pfam:PF00550"
FT DOMAIN 549..824
FT /note="Acyltransferase 3"
FT /evidence="ECO:0000259|Pfam:PF01757"
SQ SEQUENCE 841 AA; 89743 MW; 3607AE6AFCDB9D9C CRC64;
MTTDQFARVA VPARELDLTL LGGHPDDPAL VTGDRTVTYA ELAALVQRRA LELDDPGRLL
LLEMANDLPS VVTYLAALAL HRPVVIATPG AHDDIARTYR PALDADAPPP LHPDLAVLLS
TSGSTGSPKL VRLSRANVVA NARSIADYLG IRRSDRALTS LPLHYCYGLS VLNSHLVAGA
AVVLTDLSVA DECFWDLART HRATTFAGVP YTFDLLDATG FADRDLPHLR YVTQAGGRLA
PETVVRYAEL GQRRGWDLFV MYGQTEATAR MAYLPPTLAP TRPEAIGVAV PGGTLRVDLD
GPGREGLPAD VGELVYGGPN VMMGYAHGPA DLARGAELTE LRTGDLARRG PDGLWEVVGR
LNRTAKVFGL RLDLDRIERR LATAGAPARA VVVGEGLHLF TTRPRDRRVL PTHLARIAGI
PAGTVTAHVV ETVPTTASGK CDYAALRRQA EAALALAEPD AGSEAAPAYG DVTGLRDLYA
VLLGRPDATA QDTFVGLGGD SLSFVELSTR LAARIGHLPA DWPHRSIESL ALESRPARRF
TTPVELGVVL RAVAIILIVV THVDVVHLLG GAHVLLALVG YHLARFGLAV DGRRTRTRRL
LVGLAGVAVP ASLWIGGAAL LTGEYRPATA LYLNGVVGES RWSDDWQFWF LDVLVWGTLA
VALALAVPWV DRRQRRSPYA VALVALVAAL GLRYATVGVS ADLTEKYTVA GSLWLIALGW
AVAEARTRTQ RLVVAAVAAL GLVGFFPGEP SRTAIVGIGV LLLLWARPVP VPTVLAAPLR
VVAGASLWIY LTQWQVYPGL EAAGRPALAI GASLAVGVAC CCAYTRLERA VRPRLSRRRR
G
//
