ID A1T6X5_MYCVP Unreviewed; 549 AA.
AC A1T6X5;
DT 06-FEB-2007, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2007, sequence version 1.
DT 27-MAR-2024, entry version 79.
DE SubName: Full=AMP-dependent synthetase and ligase {ECO:0000313|EMBL:ABM12925.1};
GN OrderedLocusNames=Mvan_2110 {ECO:0000313|EMBL:ABM12925.1};
OS Mycolicibacterium vanbaalenii (strain DSM 7251 / JCM 13017 / BCRC 16820 /
OS KCTC 9966 / NRRL B-24157 / PYR-1) (Mycobacterium vanbaalenii).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycolicibacterium.
OX NCBI_TaxID=350058 {ECO:0000313|EMBL:ABM12925.1, ECO:0000313|Proteomes:UP000009159};
RN [1] {ECO:0000313|EMBL:ABM12925.1, ECO:0000313|Proteomes:UP000009159}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 7251 / JCM 13017 / BCRC 16820 / KCTC 9966 / NRRL B-24157 /
RC PYR-1 {ECO:0000313|Proteomes:UP000009159};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA Singan V., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N.,
RA Anderson I.J., Miller C., Richardson P.;
RT "Complete sequence of Mycobacterium vanbaalenii PYR-1.";
RL Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP000511; ABM12925.1; -; Genomic_DNA.
DR RefSeq; WP_011779339.1; NZ_JACKSD010000243.1.
DR AlphaFoldDB; A1T6X5; -.
DR STRING; 350058.Mvan_2110; -.
DR KEGG; mva:Mvan_2110; -.
DR eggNOG; COG0318; Bacteria.
DR HOGENOM; CLU_000022_59_2_11; -.
DR Proteomes; UP000009159; Chromosome.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR CDD; cd05904; 4CL; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR24096:SF149; 4-COUMARATE--COA LIGASE 1-RELATED; 1.
DR PANTHER; PTHR24096; LONG-CHAIN-FATTY-ACID--COA LIGASE; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW Ligase {ECO:0000313|EMBL:ABM12925.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000009159}.
FT DOMAIN 34..407
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 458..539
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 549 AA; 57357 MW; 12CFF58547E14B2D CRC64;
MTFLSPFPEV DIPTASVYDY LFSGLAGPED SVLDRVALID AKSGRQTTYR EMVARIDSFA
GALAARGIGV GDVVALLAPN SSVFAVAFHG ILRAGATATT VNALFTAKDI AKQLTDSKAT
MLVTVAALLP QAKAGAAAAG LSDEDVVVLD GAGRDGSGEG AGHPNAADLL AAGTPAPQVD
FAPSSHLAVL PYSSGTTGNP KGVMLTHRNL VANVAQIRPL HGMVADDVVL AVLPFFHIYG
MTVLLNAALH ARARLVIMPS FDLGEFLGNI AEHRCTIAFI APPVAVALAK HPLVDEHDLS
SLNVVMSGAA PLDADLGHAV AKRLGCKVVQ GYGMSELSPV SHITPFDGGL VDMHEDAPLS
SVGWTVSNAA SKLVDPETGD EIPIPEEGLS KTGELWFKGP NVMAGYLNND EATRSTIDED
GWLHTGDLAQ VDARGLVYIV DRLKELIKYK GYQVPPAELE ALLLSHPGIA DAAVVGVHDE
EGEEVPKAFV VRQASTDADG GAALTEADVI EFVAGQVAPY KKVRQVEFID AIPKSASGKI
LRKDLRNGG
//
