ID A1T8A6_MYCVP Unreviewed; 734 AA.
AC A1T8A6;
DT 06-FEB-2007, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2007, sequence version 1.
DT 27-MAR-2024, entry version 110.
DE SubName: Full=Putative helicase {ECO:0000313|EMBL:ABM13406.1};
GN OrderedLocusNames=Mvan_2598 {ECO:0000313|EMBL:ABM13406.1};
OS Mycolicibacterium vanbaalenii (strain DSM 7251 / JCM 13017 / BCRC 16820 /
OS KCTC 9966 / NRRL B-24157 / PYR-1) (Mycobacterium vanbaalenii).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycolicibacterium.
OX NCBI_TaxID=350058 {ECO:0000313|EMBL:ABM13406.1, ECO:0000313|Proteomes:UP000009159};
RN [1] {ECO:0000313|EMBL:ABM13406.1, ECO:0000313|Proteomes:UP000009159}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 7251 / JCM 13017 / BCRC 16820 / KCTC 9966 / NRRL B-24157 /
RC PYR-1 {ECO:0000313|Proteomes:UP000009159};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA Singan V., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N.,
RA Anderson I.J., Miller C., Richardson P.;
RT "Complete sequence of Mycobacterium vanbaalenii PYR-1.";
RL Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP000511; ABM13406.1; -; Genomic_DNA.
DR RefSeq; WP_011779815.1; NZ_JACKSD010000055.1.
DR AlphaFoldDB; A1T8A6; -.
DR STRING; 350058.Mvan_2598; -.
DR KEGG; mva:Mvan_2598; -.
DR eggNOG; COG3973; Bacteria.
DR HOGENOM; CLU_010312_3_1_11; -.
DR Proteomes; UP000009159; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR InterPro; IPR027351; (+)RNA_virus_helicase_core_dom.
DR InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR InterPro; IPR048227; HelD-like_actinomycetes.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR018647; SLFN_3-like_DNA/RNA_helicase.
DR InterPro; IPR014016; UvrD-like_ATP-bd.
DR NCBIfam; NF041465; HelD_MYCSM; 1.
DR NCBIfam; NF041258; motor_HelR_2; 1.
DR PANTHER; PTHR11070:SF45; ATP-DEPENDENT DNA HELICASE UVRD2; 1.
DR PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR Pfam; PF09848; SLFN-g3_helicase; 1.
DR Pfam; PF01443; Viral_helicase1; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00560}; Reference proteome {ECO:0000313|Proteomes:UP000009159}.
FT DOMAIN 188..602
FT /note="UvrD-like helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51198"
FT BINDING 209..216
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ SEQUENCE 734 AA; 80514 MW; 4C59A56E02C44341 CRC64;
MSTHHSTHYQ AELQSERGYV DGLYARLDAE RTRVKDRYAA ALRSPVDAQN GATLVARDAE
VRATAAQMDR LNVADAGLCF GRLDSLTGER LYIGRIGVLD DDHEPLLLDW RAPAARAFYV
ATGANPENMR RRRQFHSLGR RLLRFTDEVF GRPVADDAGE QPGSSSDVAL LAAVNAPRGD
GMRDIVATIQ AEQDAIIRLD HPGVLVIEGG PGTGKTVVAL HRVAYLLYTQ RKRMESHGVL
VVGPNAAFLR HIGRVLPSLG ETNVVFMTTG DLVPGLHVTA EDTPAAAAIK GSLAMLDVLK
AAVADRQRAP QDPLPIDLSD VSVSIGADIA QWAIQEARAG DQPHNDARAV FVDVITWALT
ERAIAKIGRG WLTRDDRAAW EHLRADLLDE LEDHTAFKAA IDQLWPKLTP EVLLAELYSS
PERLRAAGAD PALYRTDGAA WTISDVPLLD ELVDLLGRDK SAEEAAERER REEAAYAAGV
LDLMVDREDL MEDEDLLLAR DVIGAEDLAE RFLERDTREV AERAAADREW TYGHVVVDEA
QELSEMDWRV LMRRCPSRSF TMVGDLAQRR SPAGAASWAA VLEPYVPDRW MYRTLTVNYR
TPAEIMAVAA DVLAEFAPGA RPPESVRSTG VVPWARKVSD DELPSAIENF IREEADREGT
HVVIGPADVP GAVIPTETKG LEFDAVLVVH PERILAEGSR GAADLYVALT RATQRLGVLH
RDPLPQALTG LNHH
//
