ID   A1T9T2_MYCVP            Unreviewed;       247 AA.
AC   A1T9T2;
DT   06-FEB-2007, integrated into UniProtKB/TrEMBL.
DT   06-FEB-2007, sequence version 1.
DT   27-MAR-2024, entry version 82.
DE   RecName: Full=Thioesterase TesA {ECO:0000256|ARBA:ARBA00015007};
GN   OrderedLocusNames=Mvan_3130 {ECO:0000313|EMBL:ABM13932.1};
OS   Mycolicibacterium vanbaalenii (strain DSM 7251 / JCM 13017 / BCRC 16820 /
OS   KCTC 9966 / NRRL B-24157 / PYR-1) (Mycobacterium vanbaalenii).
OC   Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC   Mycolicibacterium.
OX   NCBI_TaxID=350058 {ECO:0000313|EMBL:ABM13932.1, ECO:0000313|Proteomes:UP000009159};
RN   [1] {ECO:0000313|EMBL:ABM13932.1, ECO:0000313|Proteomes:UP000009159}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 7251 / JCM 13017 / BCRC 16820 / KCTC 9966 / NRRL B-24157 /
RC   PYR-1 {ECO:0000313|Proteomes:UP000009159};
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA   Singan V., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N.,
RA   Anderson I.J., Miller C., Richardson P.;
RT   "Complete sequence of Mycobacterium vanbaalenii PYR-1.";
RL   Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a fatty acyl-CoA + H2O = a fatty acid + CoA + H(+);
CC         Xref=Rhea:RHEA:16781, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:28868, ChEBI:CHEBI:57287, ChEBI:CHEBI:77636;
CC         Evidence={ECO:0000256|ARBA:ARBA00024293};
CC   -!- SIMILARITY: Belongs to the thioesterase family.
CC       {ECO:0000256|ARBA:ARBA00007169}.
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DR   EMBL; CP000511; ABM13932.1; -; Genomic_DNA.
DR   RefSeq; WP_011780337.1; NZ_JACKSD010000048.1.
DR   AlphaFoldDB; A1T9T2; -.
DR   STRING; 350058.Mvan_3130; -.
DR   ESTHER; mycvn-q25xf5; Thioesterase.
DR   KEGG; mva:Mvan_3130; -.
DR   eggNOG; COG3208; Bacteria.
DR   HOGENOM; CLU_070456_1_2_11; -.
DR   Proteomes; UP000009159; Chromosome.
DR   GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR020802; PKS_thioesterase.
DR   InterPro; IPR012223; TEII.
DR   InterPro; IPR001031; Thioesterase.
DR   PANTHER; PTHR11487:SF0; S-ACYL FATTY ACID SYNTHASE THIOESTERASE, MEDIUM CHAIN; 1.
DR   PANTHER; PTHR11487; THIOESTERASE; 1.
DR   Pfam; PF00975; Thioesterase; 1.
DR   SMART; SM00824; PKS_TE; 1.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Reference proteome {ECO:0000313|Proteomes:UP000009159}.
FT   DOMAIN          20..241
FT                   /note="Polyketide synthase thioesterase"
FT                   /evidence="ECO:0000259|SMART:SM00824"
SQ   SEQUENCE   247 AA;  26613 MW;  CE4AA70E24F26F82 CRC64;
     MTTGGAGESS AGQPKLFIFP HAGGSAQYYV PFAKTFATDI KRVAVQYPGQ RGKQDFASFT
     SLPALADEVC KMVSPDKEGG VHGPPIAFFG HSMGGLLAFE VARRFEEAGR PIAALFVSAV
     AAPGRVGYED IPDDDEGLLA AVSSMTGANP EFMKNPEFAA AILPTLRGLK AIANYTCPPD
     VTLSCPIHAF YGDDDEIATA DKVKPWAERT TADFTAREFS GHHFYLNDHL GELVPDLEQK
     LWSRLRE
//