ID A1THU2_MYCVP Unreviewed; 292 AA.
AC A1THU2;
DT 06-FEB-2007, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2007, sequence version 1.
DT 27-MAR-2024, entry version 82.
DE RecName: Full=Peptidase M10 metallopeptidase domain-containing protein {ECO:0000259|Pfam:PF00413};
GN OrderedLocusNames=Mvan_5986 {ECO:0000313|EMBL:ABM16742.1};
OS Mycolicibacterium vanbaalenii (strain DSM 7251 / JCM 13017 / BCRC 16820 /
OS KCTC 9966 / NRRL B-24157 / PYR-1) (Mycobacterium vanbaalenii).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycolicibacterium.
OX NCBI_TaxID=350058 {ECO:0000313|EMBL:ABM16742.1, ECO:0000313|Proteomes:UP000009159};
RN [1] {ECO:0000313|EMBL:ABM16742.1, ECO:0000313|Proteomes:UP000009159}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 7251 / JCM 13017 / BCRC 16820 / KCTC 9966 / NRRL B-24157 /
RC PYR-1 {ECO:0000313|Proteomes:UP000009159};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA Singan V., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N.,
RA Anderson I.J., Miller C., Richardson P.;
RT "Complete sequence of Mycobacterium vanbaalenii PYR-1.";
RL Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP000511; ABM16742.1; -; Genomic_DNA.
DR RefSeq; WP_011783086.1; NZ_JACKSD010000159.1.
DR AlphaFoldDB; A1THU2; -.
DR STRING; 350058.Mvan_5986; -.
DR MEROPS; M10.068; -.
DR KEGG; mva:Mvan_5986; -.
DR eggNOG; COG5549; Bacteria.
DR HOGENOM; CLU_952554_0_0_11; -.
DR Proteomes; UP000009159; Chromosome.
DR GO; GO:0031012; C:extracellular matrix; IEA:InterPro.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR Gene3D; 3.40.390.10; Collagenase (Catalytic Domain); 1.
DR InterPro; IPR024079; MetalloPept_cat_dom_sf.
DR InterPro; IPR001818; Pept_M10_metallopeptidase.
DR Pfam; PF00413; Peptidase_M10; 1.
DR SUPFAM; SSF55486; Metalloproteases ('zincins'), catalytic domain; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000009159};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 40..61
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 171..269
FT /note="Peptidase M10 metallopeptidase"
FT /evidence="ECO:0000259|Pfam:PF00413"
FT REGION 83..104
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 292 AA; 31066 MW; 968424FCFFC53BE1 CRC64;
MTPLIRGRHG TATDLVAFRA RYSSPRPTGR HQPEPRSAGS LFAGFPALLI VVALLIGSAL
LSHPEPAATT PYVAAGGAAP VADRPIQPSA APTPTPEQEP QQSVFSPIAR PAHPWLDEEP
GGEPVAWACA PIGYRVVLEG APAGVEQLLA EATARISAVS GHQFRADRPL HWLEERSTPY
VGITVAWVAR AEHPEASQDA IAIARTTTTP TPSGGSLYSA GKVHIFSDWP GAHRMNFTAN
GVGPVMLHEL GHALGLGHSD DRDAMMHPTN LGVTTWSEPE RAALRYLRQS CR
//
