ID A1WRN6_VEREI Unreviewed; 273 AA.
AC A1WRN6;
DT 06-FEB-2007, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2007, sequence version 1.
DT 27-MAR-2024, entry version 81.
DE SubName: Full=D-aminopeptidase DppA. Metallo peptidase. MEROPS family M55 {ECO:0000313|EMBL:ABM60293.1};
GN OrderedLocusNames=Veis_4595 {ECO:0000313|EMBL:ABM60293.1};
OS Verminephrobacter eiseniae (strain EF01-2).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Comamonadaceae; Verminephrobacter.
OX NCBI_TaxID=391735 {ECO:0000313|EMBL:ABM60293.1, ECO:0000313|Proteomes:UP000000374};
RN [1] {ECO:0000313|Proteomes:UP000000374}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EF01-2 {ECO:0000313|Proteomes:UP000000374};
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T.,
RA Bruce D., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M.,
RA Hauser L., Kyrpides N., Kim E., Stahl D., Richardson P.;
RT "Complete sequence of chromosome 1 of Verminephrobacter eiseniae EF01-2.";
RL Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP000542; ABM60293.1; -; Genomic_DNA.
DR RefSeq; WP_011812277.1; NC_008786.1.
DR AlphaFoldDB; A1WRN6; -.
DR STRING; 391735.Veis_4595; -.
DR GeneID; 76462885; -.
DR KEGG; vei:Veis_4595; -.
DR eggNOG; COG2362; Bacteria.
DR HOGENOM; CLU_086038_1_1_4; -.
DR OrthoDB; 9785420at2; -.
DR Proteomes; UP000000374; Chromosome.
DR GO; GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd08663; DAP_dppA_1; 1.
DR Gene3D; 3.30.1360.130; Dipeptide transport protein; 1.
DR Gene3D; 3.40.50.10780; Dipeptide transport protein; 1.
DR InterPro; IPR027476; DppA_N.
DR InterPro; IPR007035; Peptidase_M55.
DR InterPro; IPR036177; Peptidase_M55_sf.
DR Pfam; PF04951; Peptidase_M55; 1.
DR PIRSF; PIRSF015853; Pep_DppA; 1.
DR SUPFAM; SSF63992; Dipeptide transport protein; 1.
PE 4: Predicted;
KW Aminopeptidase {ECO:0000313|EMBL:ABM60293.1};
KW Hydrolase {ECO:0000313|EMBL:ABM60293.1};
KW Metal-binding {ECO:0000256|PIRSR:PIRSR015853-2};
KW Protease {ECO:0000313|EMBL:ABM60293.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000000374};
KW Zinc {ECO:0000256|PIRSR:PIRSR015853-2}.
FT ACT_SITE 116
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PIRSR:PIRSR015853-1"
FT BINDING 8
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /evidence="ECO:0000256|PIRSR:PIRSR015853-2"
FT BINDING 8
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="1"
FT /evidence="ECO:0000256|PIRSR:PIRSR015853-2"
FT BINDING 10
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="1"
FT /evidence="ECO:0000256|PIRSR:PIRSR015853-2"
FT BINDING 60
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /evidence="ECO:0000256|PIRSR:PIRSR015853-2"
FT BINDING 105
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /evidence="ECO:0000256|PIRSR:PIRSR015853-2"
FT BINDING 135
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /evidence="ECO:0000256|PIRSR:PIRSR015853-2"
SQ SEQUENCE 273 AA; 29225 MW; 0D872D101D0FF3DD CRC64;
MKVLISTDIE GVAGVYHHEQ TRQGNPEYER ARVLMAHEAN AAIAGAFDAG ATEVLVNDSH
GGFRNMPPDM LDARARVVQG KPRYLSMVAG VEEDGVQALC MLGYHSRAQG RGILAHTING
FAFAGIRFGD QELGEAGIYG ALAGAYGVPV VMGSGDDMFI AENRALFPHA TFVQTKKATG
FNSGVSLSSE QSRQAIRAGV IEALAARANA RPLVFKGPQV VTLRTQSPMM ADLFCQWPSF
ERVDGVTLRF SADTVEAAVR VLNCCSAMSS MLR
//
