ID A1WUY9_HALHL Unreviewed; 360 AA.
AC A1WUY9;
DT 06-FEB-2007, integrated into UniProtKB/TrEMBL.
DT 06-FEB-2007, sequence version 1.
DT 24-JAN-2024, entry version 86.
DE RecName: Full=Ion-translocating oxidoreductase complex subunit A {ECO:0000256|HAMAP-Rule:MF_00459};
DE EC=7.-.-.- {ECO:0000256|HAMAP-Rule:MF_00459};
DE AltName: Full=Rnf electron transport complex subunit A {ECO:0000256|HAMAP-Rule:MF_00459};
GN Name=rnfA {ECO:0000256|HAMAP-Rule:MF_00459};
GN OrderedLocusNames=Hhal_0719 {ECO:0000313|EMBL:ABM61501.1};
OS Halorhodospira halophila (strain DSM 244 / SL1) (Ectothiorhodospira
OS halophila (strain DSM 244 / SL1)).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Chromatiales;
OC Ectothiorhodospiraceae; Halorhodospira.
OX NCBI_TaxID=349124 {ECO:0000313|EMBL:ABM61501.1, ECO:0000313|Proteomes:UP000000647};
RN [1] {ECO:0000313|Proteomes:UP000000647}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 244 / SL1 {ECO:0000313|Proteomes:UP000000647};
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA Saunders E., Brettin T., Bruce D., Han C., Tapia R., Schmutz J.,
RA Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Hoff W.,
RA Richardson P.;
RT "Complete sequence of Halorhodospira halophila SL1.";
RL Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ABM61501.1, ECO:0000313|Proteomes:UP000000647}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 244 / SL1 {ECO:0000313|Proteomes:UP000000647};
RX PubMed=23991253; DOI=10.4056/sigs.3677284;
RA Challacombe J.F., Majid S., Deole R., Brettin T.S., Bruce D., Delano S.F.,
RA Detter J.C., Gleasner C.D., Han C.S., Misra M., Reitenga K.G.,
RA Mikhailova N., Woyke T., Pitluck S., Nolan M., Land M.L., Saunders E.,
RA Tapia R., Lapidus A., Ivanova N., Hoff W.D.;
RT "Complete genome sequence of Halorhodospira halophila SL1.";
RL Stand. Genomic Sci. 8:206-214(2013).
CC -!- FUNCTION: Part of a membrane-bound complex that couples electron
CC transfer with translocation of ions across the membrane.
CC {ECO:0000256|HAMAP-Rule:MF_00459}.
CC -!- SUBUNIT: The complex is composed of six subunits: RnfA, RnfB, RnfC,
CC RnfD, RnfE and RnfG. {ECO:0000256|HAMAP-Rule:MF_00459}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000256|HAMAP-
CC Rule:MF_00459}; Multi-pass membrane protein {ECO:0000256|HAMAP-
CC Rule:MF_00459}. Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass
CC membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the NqrDE/RnfAE family. {ECO:0000256|HAMAP-
CC Rule:MF_00459}.
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DR EMBL; CP000544; ABM61501.1; -; Genomic_DNA.
DR AlphaFoldDB; A1WUY9; -.
DR STRING; 349124.Hhal_0719; -.
DR KEGG; hha:Hhal_0719; -.
DR eggNOG; COG1259; Bacteria.
DR eggNOG; COG4657; Bacteria.
DR HOGENOM; CLU_768964_0_0_6; -.
DR Proteomes; UP000000647; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004518; F:nuclease activity; IEA:InterPro.
DR GO; GO:0022900; P:electron transport chain; IEA:UniProtKB-UniRule.
DR Gene3D; 3.10.690.10; Bifunctional nuclease domain; 1.
DR HAMAP; MF_00459; RsxA_RnfA; 1.
DR InterPro; IPR036104; BFN_sf.
DR InterPro; IPR003729; Bi_nuclease_dom.
DR InterPro; IPR011293; Ion_transpt_RnfA/RsxA.
DR InterPro; IPR003667; NqrDE/RnfAE.
DR NCBIfam; TIGR01943; rnfA; 1.
DR PANTHER; PTHR30335; INTEGRAL MEMBRANE PROTEIN OF SOXR-REDUCING COMPLEX; 1.
DR PANTHER; PTHR30335:SF0; ION-TRANSLOCATING OXIDOREDUCTASE COMPLEX SUBUNIT A; 1.
DR Pfam; PF02577; BFN_dom; 1.
DR Pfam; PF02508; Rnf-Nqr; 1.
DR SUPFAM; SSF103256; Hypothetical protein TM0160; 1.
DR PROSITE; PS51658; BFN; 1.
PE 3: Inferred from homology;
KW Cell inner membrane {ECO:0000256|ARBA:ARBA00022519, ECO:0000256|HAMAP-
KW Rule:MF_00459}; Cell membrane {ECO:0000256|HAMAP-Rule:MF_00459};
KW Electron transport {ECO:0000256|ARBA:ARBA00022982, ECO:0000256|HAMAP-
KW Rule:MF_00459};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|HAMAP-Rule:MF_00459};
KW Reference proteome {ECO:0000313|Proteomes:UP000000647};
KW Translocase {ECO:0000256|ARBA:ARBA00022967, ECO:0000256|HAMAP-
KW Rule:MF_00459};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|HAMAP-
KW Rule:MF_00459};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, ECO:0000256|HAMAP-
KW Rule:MF_00459};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|HAMAP-Rule:MF_00459}.
FT TRANSMEM 6..28
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00459"
FT TRANSMEM 40..64
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00459"
FT TRANSMEM 70..91
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00459"
FT TRANSMEM 103..123
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00459"
FT TRANSMEM 129..153
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00459"
FT TRANSMEM 165..189
FT /note="Helical"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00459"
FT DOMAIN 204..338
FT /note="BFN"
FT /evidence="ECO:0000259|PROSITE:PS51658"
FT REGION 335..360
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 335..350
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 360 AA; 38205 MW; B9D54DE961FD2674 CRC64;
MDLLLLAVAA VLVNNFVLTQ FLGLCPFLGV SRKVETAAGM AAATAFVLTL ASVLSYLAFT
YILVPLDAEY LRTPTFILII AIAVQLTEMA VRFTSPMLQQ VLGLYLPLIT TNCAVLGVAL
LNLRGDHDLI ASAVYGAAAA AGFGLVLVIF AALRERLESA EVPRAFRGAP IALVSAGILS
MGFMGFAGLA QAGERELATD REDMVEVEVT TLTLEEGGAP APVILLGEPD SEQMVPIFIG
PSEAQAIHDA LHGVEPPRPM THDLFGNVLR ATGYTLQAVY IDAIVDGAYV AALALAPEDG
GEVRYIDSRS SDAIALALRA EATIYAAPEV LEAAQEREQQ RPRDESLRMT RLDLVPGPTT
//
