ID A2ACV5_MOUSE Unreviewed; 232 AA.
AC A2ACV5;
DT 20-FEB-2007, integrated into UniProtKB/TrEMBL.
DT 20-FEB-2007, sequence version 1.
DT 27-MAR-2024, entry version 89.
DE SubName: Full=DSN1 homolog, MIS12 kinetochore complex component {ECO:0000313|Ensembl:ENSMUSP00000122524.2};
DE Flags: Fragment;
GN Name=Dsn1 {ECO:0000313|Ensembl:ENSMUSP00000122524.2,
GN ECO:0000313|MGI:MGI:1914184};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000122524.2, ECO:0000313|Proteomes:UP000000589};
RN [1] {ECO:0000313|Ensembl:ENSMUSP00000122524.2, ECO:0000313|Proteomes:UP000000589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000122524.2,
RC ECO:0000313|Proteomes:UP000000589};
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [2] {ECO:0000313|Ensembl:ENSMUSP00000122524.2}
RP IDENTIFICATION.
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000122524.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; A2ACV5; -.
DR SMR; A2ACV5; -.
DR jPOST; A2ACV5; -.
DR MaxQB; A2ACV5; -.
DR PeptideAtlas; A2ACV5; -.
DR ProteomicsDB; 306433; -.
DR Antibodypedia; 1232; 206 antibodies from 26 providers.
DR Ensembl; ENSMUST00000146413.8; ENSMUSP00000122524.2; ENSMUSG00000027635.16.
DR AGR; MGI:1914184; -.
DR MGI; MGI:1914184; Dsn1.
DR VEuPathDB; HostDB:ENSMUSG00000027635; -.
DR GeneTree; ENSGT00390000011347; -.
DR Proteomes; UP000000589; Chromosome 2.
DR Bgee; ENSMUSG00000027635; Expressed in animal zygote and 198 other cell types or tissues.
DR ExpressionAtlas; A2ACV5; baseline and differential.
DR GO; GO:0000444; C:MIS12/MIND type complex; IEA:InterPro.
DR GO; GO:0051301; P:cell division; IEA:InterPro.
DR GO; GO:0007059; P:chromosome segregation; IEA:InterPro.
DR InterPro; IPR013218; Dsn1/Mis13.
DR PANTHER; PTHR14778; KINETOCHORE-ASSOCIATED PROTEIN DSN1 HOMOLOG; 1.
DR PANTHER; PTHR14778:SF2; KINETOCHORE-ASSOCIATED PROTEIN DSN1 HOMOLOG; 1.
DR Pfam; PF08202; MIS13; 1.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|EPD:A2ACV5,
KW ECO:0007829|MaxQB:A2ACV5};
KW Reference proteome {ECO:0000313|Proteomes:UP000000589}.
FT REGION 1..105
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..22
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 29..51
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 68..87
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 88..105
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 232
FT /evidence="ECO:0000313|Ensembl:ENSMUSP00000122524.2"
SQ SEQUENCE 232 AA; 26447 MW; 931210E9BC15C32B CRC64;
MTSVTRSEDQ EPTMSETQDR PLQPSLKPLE ALPQSSAYQE MMTQGVSEEK NHLGSNPGEG
ESCGADHQEG SQLRSFHLSP QEQSIRPQDR RQSWRRASMK EVNRRKSLAP FHPGITELCR
SISVKLAQSQ RLGALLLSSF QFSVEKLEPF LKNTKDFSLE CFRAKASSLS EELKHFTDRL
GNDGTLQKCF VEDSKEFSLE RQAWDRLLLQ YQNEVPPEEM PRGSTETRIT EV
//
