ID A2AKS7_MOUSE Unreviewed; 728 AA.
AC A2AKS7;
DT 20-FEB-2007, integrated into UniProtKB/TrEMBL.
DT 20-FEB-2007, sequence version 1.
DT 27-MAR-2024, entry version 130.
DE SubName: Full=Cadherin 17 {ECO:0000313|Ensembl:ENSMUSP00000103938.2};
GN Name=Cdh17 {ECO:0000313|Ensembl:ENSMUSP00000103938.2,
GN ECO:0000313|MGI:MGI:1095414};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000103938.2, ECO:0000313|Proteomes:UP000000589};
RN [1] {ECO:0000313|Ensembl:ENSMUSP00000103938.2, ECO:0000313|Proteomes:UP000000589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000103938.2,
RC ECO:0000313|Proteomes:UP000000589};
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [2] {ECO:0000313|Ensembl:ENSMUSP00000103938.2}
RP IDENTIFICATION.
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000103938.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; A2AKS7; -.
DR SMR; A2AKS7; -.
DR MaxQB; A2AKS7; -.
DR PeptideAtlas; A2AKS7; -.
DR ProteomicsDB; 332331; -.
DR Antibodypedia; 12841; 616 antibodies from 42 providers.
DR Ensembl; ENSMUST00000108303.2; ENSMUSP00000103938.2; ENSMUSG00000028217.12.
DR UCSC; uc008rzx.2; mouse.
DR AGR; MGI:1095414; -.
DR MGI; MGI:1095414; Cdh17.
DR VEuPathDB; HostDB:ENSMUSG00000028217; -.
DR GeneTree; ENSGT00940000157655; -.
DR Proteomes; UP000000589; Chromosome 4.
DR Bgee; ENSMUSG00000028217; Expressed in small intestine Peyer's patch and 43 other cell types or tissues.
DR ExpressionAtlas; A2AKS7; baseline and differential.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0005509; F:calcium ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0007156; P:homophilic cell adhesion via plasma membrane adhesion molecules; IEA:InterPro.
DR CDD; cd11304; Cadherin_repeat; 6.
DR Gene3D; 2.60.40.60; Cadherins; 6.
DR InterPro; IPR039808; Cadherin.
DR InterPro; IPR002126; Cadherin-like_dom.
DR InterPro; IPR015919; Cadherin-like_sf.
DR InterPro; IPR020894; Cadherin_CS.
DR PANTHER; PTHR24027:SF419; CADHERIN-17; 1.
DR PANTHER; PTHR24027; CADHERIN-23; 1.
DR Pfam; PF00028; Cadherin; 5.
DR PRINTS; PR00205; CADHERIN.
DR SMART; SM00112; CA; 6.
DR SUPFAM; SSF49313; Cadherin-like; 6.
DR PROSITE; PS00232; CADHERIN_1; 3.
DR PROSITE; PS50268; CADHERIN_2; 5.
PE 1: Evidence at protein level;
KW Calcium {ECO:0000256|ARBA:ARBA00022837, ECO:0000256|PROSITE-
KW ProRule:PRU00043}; Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Proteomics identification {ECO:0007829|EPD:A2AKS7,
KW ECO:0007829|MaxQB:A2AKS7};
KW Reference proteome {ECO:0000313|Proteomes:UP000000589};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..728
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5015086017"
FT DOMAIN 57..125
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 126..339
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 340..448
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 457..565
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 566..666
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
SQ SEQUENCE 728 AA; 80654 MW; 0EDE7E7F7A3F2CA4 CRC64;
MVSAQLHFLC LLTLYLTCGY GEEGKFSGPL KPMTFSIFEG QEPSQVIFQF KTNPPAVTFE
LTGETDGIFK IEKDGLLYHT RALDRETRAV HHLQLAALDS HGAIVDGPVP ITIEVKDIND
NRPTFLQSKY EGSVRQNSRP GKPFMYVNAT DLDDPATPNG QLFYQIVIQL PQINDVMYFQ
IDSKTGAISL TPEGSQELDP VKNPSYNLVV SVKDMGGQSE NSFSDTTYVD ISIRENIWKA
PEPVEIRENS TDPHPIKITQ VQWNDPGAQY SLVNKEKLSP FPFSIDQEGN IYVTQALDRE
EKNSHVFFAT AKDENGKPLA YPLEIYVKVI DINDNPPTCL SPVTVFEVQE NEPLGNSIGI
FEAHDMDEAN NINSILKYKL VDQTPKVPSD GLFLIGEYEG KVQLSKQSLK KQDSPQYNLS
IEVSDVDFKT LCYIQVNVID INDQIPIFET SNYGSKTLSE DTAIGSTILI IQATDADEPF
TGSSKILYKI VQGDTEGRLE VVTDPTTNAG YVKIKKPLDF ETQPVSSIVF QAENPEPLVK
GIEYNASSFA SFELIVTDVN EVPVFPQRIF QANVSEDAAV GSRVGNVTAR DPEGLTVSYS
LKGNMRGWLK IDSVTGEIFS AAPLDRETES VYRVQVVATE VGGSSLSSTA DFHLVLTDVN
DNPPRLAKDY TGLFFCHPLS APGSLIFEVT DDDQQSLRRP KFTFALGREG LQSDWEVSKI
NGELSNVQ
//
