ID A2AQR4_MOUSE Unreviewed; 676 AA.
AC A2AQR4;
DT 20-FEB-2007, integrated into UniProtKB/TrEMBL.
DT 20-FEB-2007, sequence version 1.
DT 27-MAR-2024, entry version 121.
DE SubName: Full=Zinc finger protein 64 {ECO:0000313|Ensembl:ENSMUSP00000085285.5};
GN Name=Zfp64 {ECO:0000313|Ensembl:ENSMUSP00000085285.5,
GN ECO:0000313|MGI:MGI:107342};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000085285.5, ECO:0000313|Proteomes:UP000000589};
RN [1] {ECO:0000313|Ensembl:ENSMUSP00000085285.5, ECO:0000313|Proteomes:UP000000589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000085285.5,
RC ECO:0000313|Proteomes:UP000000589};
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [2] {ECO:0000313|Ensembl:ENSMUSP00000085285.5}
RP IDENTIFICATION.
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000085285.5};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR RefSeq; NP_033590.2; NM_009564.2.
DR AlphaFoldDB; A2AQR4; -.
DR SMR; A2AQR4; -.
DR IntAct; A2AQR4; 2.
DR EPD; A2AQR4; -.
DR MaxQB; A2AQR4; -.
DR PeptideAtlas; A2AQR4; -.
DR ProteomicsDB; 329207; -.
DR Antibodypedia; 13873; 235 antibodies from 26 providers.
DR DNASU; 22722; -.
DR Ensembl; ENSMUST00000087971.11; ENSMUSP00000085285.5; ENSMUSG00000027551.16.
DR GeneID; 22722; -.
DR UCSC; uc008obk.1; mouse.
DR AGR; MGI:107342; -.
DR CTD; 55734; -.
DR MGI; MGI:107342; Zfp64.
DR VEuPathDB; HostDB:ENSMUSG00000027551; -.
DR eggNOG; KOG1721; Eukaryota.
DR GeneTree; ENSGT00940000156405; -.
DR HOGENOM; CLU_002678_71_1_1; -.
DR OrthoDB; 4036417at2759; -.
DR PhylomeDB; A2AQR4; -.
DR TreeFam; TF333046; -.
DR BioGRID-ORCS; 22722; 2 hits in 64 CRISPR screens.
DR ChiTaRS; Zfp64; mouse.
DR Proteomes; UP000000589; Chromosome 2.
DR Bgee; ENSMUSG00000027551; Expressed in ectoplacental cone and 210 other cell types or tissues.
DR ExpressionAtlas; A2AQR4; baseline and differential.
DR GO; GO:0005737; C:cytoplasm; IEA:Ensembl.
DR GO; GO:0043076; C:megasporocyte nucleus; IEA:Ensembl.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0048762; P:mesenchymal cell differentiation; IEA:Ensembl.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 8.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR24403:SF43; RCG32340, ISOFORM CRA_A; 1.
DR PANTHER; PTHR24403; ZINC FINGER PROTEIN; 1.
DR Pfam; PF00096; zf-C2H2; 5.
DR Pfam; PF13912; zf-C2H2_6; 1.
DR Pfam; PF13909; zf-H2C2_5; 1.
DR Pfam; PF12874; zf-met; 1.
DR SMART; SM00355; ZnF_C2H2; 11.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 6.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 5.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 9.
PE 1: Evidence at protein level;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Proteomics identification {ECO:0007829|EPD:A2AQR4,
KW ECO:0007829|PeptideAtlas:A2AQR4};
KW Reference proteome {ECO:0000313|Proteomes:UP000000589};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00042}.
FT DOMAIN 173..200
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 201..228
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 229..256
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 257..284
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 285..313
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 313..340
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 341..368
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 369..393
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 423..450
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
SQ SEQUENCE 676 AA; 74035 MW; A6D4BF424F2DF9F1 CRC64;
MNASVEGDTF SGSMQIPGGT TVLVELAPDI HICGLCKQHF SNLDAFVAHK QSGCQLTTTP
VTAPSTVQFV AEETEPATQT TTTTISSETQ TITVSAPEFV FEHGYQTYLP TESTDNQTAT
VISLPTKSRT KKPTAPPAQK RLGCCYPGCQ FKTAYGMKDM ERHLKIHTGD KPHKCEVCGK
CFSRKDKLKT HMRCHTGVKP YKCKTCDYAA ADSSSLNKHL RIHSDERPFK CQICPYASRN
SSQLTVHLRS HTGDAPFQCW LCSAKFKISS DLKRHMRVHS GEKPFKCEFC NVRCTMKGNL
KSHIRIKHSG NNFKCPHCDF LGDSKSTLRK HSRLHQSEHP EKCPECSYSC SSKAALRVHE
RIHCTERPFK CSYCSFDTKQ PSNLSKHMKK FHADMLKNEA PEKKESGRQS SRQVARLDAK
KTFHCDICDA SFMREDSLRS HKRQHSEYHS KNSDVTVVQL HLEPSKQPAA PLTVEQIQVP
LQSSQVPQFS EGRVKIIVGH QVPQTNAIVQ AAAAAVNIVP PTLVAQTPEE IPGNGRLQIL
RQVSLIAPPQ SSGCPGEAGA LSQPTVLLTT HDQTAGAALQ QALIPTTPVG TQEGTGNQTF
IASSGITCSD LEGLNALIQE GTTEVTVVSD GDQSIAVATT APSIFSTQQE LPKQTYSIIH
GAAHPALLCP ADSIPD
//
