ID A2BJ88_HYPBU Unreviewed; 264 AA.
AC A2BJ88;
DT 20-FEB-2007, integrated into UniProtKB/TrEMBL.
DT 20-FEB-2007, sequence version 1.
DT 27-MAR-2024, entry version 69.
DE SubName: Full=Fe-S oxidoreductase {ECO:0000313|EMBL:ABM80049.1};
GN OrderedLocusNames=Hbut_0177 {ECO:0000313|EMBL:ABM80049.1};
OS Hyperthermus butylicus (strain DSM 5456 / JCM 9403 / PLM1-5).
OC Archaea; Thermoproteota; Thermoprotei; Desulfurococcales; Pyrodictiaceae;
OC Hyperthermus.
OX NCBI_TaxID=415426 {ECO:0000313|EMBL:ABM80049.1, ECO:0000313|Proteomes:UP000002593};
RN [1] {ECO:0000313|EMBL:ABM80049.1, ECO:0000313|Proteomes:UP000002593}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 5456 / JCM 9403 / PLM1-5
RC {ECO:0000313|Proteomes:UP000002593};
RX PubMed=17350933;
RA Brugger K., Chen L., Stark M., Zibat A., Redder P., Ruepp A., Awayez M.,
RA She Q., Garrett R.A., Klenk H.P.;
RT "The genome of Hyperthermus butylicus: a sulfur-reducing, peptide
RT fermenting, neutrophilic Crenarchaeote growing up to 108 degrees C.";
RL Archaea 2:127-135(2007).
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
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DR EMBL; CP000493; ABM80049.1; -; Genomic_DNA.
DR RefSeq; WP_011821366.1; NC_008818.1.
DR AlphaFoldDB; A2BJ88; -.
DR STRING; 415426.Hbut_0177; -.
DR EnsemblBacteria; ABM80049; ABM80049; Hbut_0177.
DR GeneID; 4781613; -.
DR KEGG; hbu:Hbut_0177; -.
DR eggNOG; arCOG05120; Archaea.
DR HOGENOM; CLU_1080107_0_0_2; -.
DR OrthoDB; 5620at2157; -.
DR Proteomes; UP000002593; Chromosome.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd01335; Radical_SAM; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR007197; rSAM.
DR PANTHER; PTHR43787; FEMO COFACTOR BIOSYNTHESIS PROTEIN NIFB-RELATED; 1.
DR PANTHER; PTHR43787:SF12; RADICAL SAM CORE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF13353; Fer4_12; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR SFLD; SFLDS00029; Radical_SAM; 1.
DR SFLD; SFLDG01067; SPASM/twitch_domain_containing; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 4: Predicted;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000002593};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691}.
FT DOMAIN 35..249
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
SQ SEQUENCE 264 AA; 30449 MW; 84BEA642BBA25320 CRC64;
MLSRGYDPVR LAELVAERVA PWSGGMRLRR YYRFRRDRWY GGIVTGDVVG CNLRCRFCWA
WRFTWTGYGR GVLLSPDEAA ERLMRLARRT RVRQVRLSGG EPTVGWEHLL EVMEAVTGEG
LHFVLETNGI LIGAYEELAR RLASFHGAGV EVRVSIKGTS EEEFYMLTGA RPEAWRLQLR
ALKLLVDYGL EPGEEVYPAV MLSFTDERGV TRIKRLLYAI HPRLAENIDP EYVILYPHVV
ELMRRTGLRP RKAYRPDEVP PELV
//
