ID   A2BMA9_HYPBU            Unreviewed;       955 AA.
AC   A2BMA9;
DT   20-FEB-2007, integrated into UniProtKB/TrEMBL.
DT   20-FEB-2007, sequence version 1.
DT   27-MAR-2024, entry version 91.
DE   SubName: Full=DEAD/DEAH box helicase {ECO:0000313|EMBL:ABM81120.1};
GN   OrderedLocusNames=Hbut_1290 {ECO:0000313|EMBL:ABM81120.1};
OS   Hyperthermus butylicus (strain DSM 5456 / JCM 9403 / PLM1-5).
OC   Archaea; Thermoproteota; Thermoprotei; Desulfurococcales; Pyrodictiaceae;
OC   Hyperthermus.
OX   NCBI_TaxID=415426 {ECO:0000313|EMBL:ABM81120.1, ECO:0000313|Proteomes:UP000002593};
RN   [1] {ECO:0000313|EMBL:ABM81120.1, ECO:0000313|Proteomes:UP000002593}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 5456 / JCM 9403 / PLM1-5
RC   {ECO:0000313|Proteomes:UP000002593};
RX   PubMed=17350933;
RA   Brugger K., Chen L., Stark M., Zibat A., Redder P., Ruepp A., Awayez M.,
RA   She Q., Garrett R.A., Klenk H.P.;
RT   "The genome of Hyperthermus butylicus: a sulfur-reducing, peptide
RT   fermenting, neutrophilic Crenarchaeote growing up to 108 degrees C.";
RL   Archaea 2:127-135(2007).
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DR   EMBL; CP000493; ABM81120.1; -; Genomic_DNA.
DR   RefSeq; WP_011822438.1; NC_008818.1.
DR   AlphaFoldDB; A2BMA9; -.
DR   STRING; 415426.Hbut_1290; -.
DR   EnsemblBacteria; ABM81120; ABM81120; Hbut_1290.
DR   GeneID; 4782050; -.
DR   KEGG; hbu:Hbut_1290; -.
DR   eggNOG; arCOG00557; Archaea.
DR   HOGENOM; CLU_002025_0_0_2; -.
DR   OrthoDB; 33870at2157; -.
DR   Proteomes; UP000002593; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR013701; DEAD/DEAH_assoc.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR017170; Lhr-like_ATP-dep_RNA_helic_prd.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR47962:SF5; ATP-DEPENDENT HELICASE LHR-RELATED; 1.
DR   PANTHER; PTHR47962; ATP-DEPENDENT HELICASE LHR-RELATED-RELATED; 1.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF08494; DEAD_assoc; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   PIRSF; PIRSF037307; Lhr-like_helic_prd; 1.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Helicase {ECO:0000313|EMBL:ABM81120.1};
KW   Hydrolase {ECO:0000313|EMBL:ABM81120.1};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002593}.
FT   DOMAIN          41..221
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
FT   DOMAIN          262..413
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51194"
SQ   SEQUENCE   955 AA;  107357 MW;  A20EDAC7F10F722A CRC64;
     MPRGFGQTSV QGAFRLLHPV LRAVLPRYGY IRPTEIQEKA IPLILRGNHV LIVAPTGSGK
     TEAALLPAMS SILPMRGFTG KIYVVYITPL RSLNRDIFAR MKSLASSVGL RLEVRHGDST
     ELEKRRFLEN PPHIMITTPE SFYFLLSVEK FREAISELKY VIVDEVHELV GDKRGAELSL
     ALERAISLYV KGKVQLVGLS ATVAEPELVV RKLFGSRYVR IVEASMARKY NVGVVLPSRD
     NTVNGLELSE FNEELYEDTI DRIAYIANVI REKGSVIVFT NTRDTAELIG ALLKKVLGEN
     SIEVHHGSLS REHRLSIEER FRKGEIAALV ATSSLELGID IGHVGYVVQY LSPRQVVKLV
     QRVGRARHRA GEAAAGVVVA SRNLFDVLES AVIAARTSRG NLEKLKPPHA PLDALVHQVA
     GTVIENPGID IGKLYLLVTR SGFYEGLDFD EFMAVLSYME HAGIIRIRDG KLYPGRKCMS
     YYFNSTMITE SIQYPVYDVV SGKRIGLLDE EFVASLDVGE KFVLAGRVWE VVGFDENGVR
     VKPSSEDRLI PPAWEGDLIP VEHNVAREVA SILRRFGEGH TEVLDMYPLS DTARRYVGEK
     LLQAMRELGF LPHDRRILVE HYGDTYVVYV FLGSRGNKSL EYLLAYYISQ IKGYNVLSAS
     TPYAIVLKLP ERSEPGLVEM VIKRLAELPP STLEEMYVEA VKKSRLYSWI LYRVAQRAGA
     LPASRRARDP SMLKRVVAQL ANTILGVEAL REFENRKGNL EVVKALLRDV GKGYVLISTV
     SRRNPSPLTE DIISEALFSD RVVRTQMPAT LVAEAVKRRI KARQVILICL VCGYKWQRRV
     SELPQEIKCP NCSSKLVYVT TVEEKARDAS MLAMKRKRVG LSRSENKRMR EYIEVANLVM
     DYGRYAVEAL VARGVGVSTA RRVLQKLVFS EDAFYKALVE AEAKYYKYAY KLRKK
//