ID A2QBP9_ASPNC Unreviewed; 401 AA.
AC A2QBP9;
DT 06-MAR-2007, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2007, sequence version 1.
DT 27-MAR-2024, entry version 80.
DE SubName: Full=Contig An02c0010, genomic contig {ECO:0000313|EMBL:CAK96296.1};
DE EC=2.1.1.109 {ECO:0000313|EMBL:CAK96296.1};
GN ORFNames=An02g00810 {ECO:0000313|EMBL:CAK96296.1};
OS Aspergillus niger (strain ATCC MYA-4892 / CBS 513.88 / FGSC A1513).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Circumdati.
OX NCBI_TaxID=425011 {ECO:0000313|EMBL:CAK96296.1, ECO:0000313|Proteomes:UP000006706};
RN [1] {ECO:0000313|EMBL:CAK96296.1, ECO:0000313|Proteomes:UP000006706}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 513.88 / FGSC A1513 / ATCC MYA-4892
RC {ECO:0000313|Proteomes:UP000006706};
RX PubMed=17259976; DOI=10.1038/nbt1282;
RA Pel H.J., de Winde J.H., Archer D.B., Dyer P.S., Hofmann G., Schaap P.J.,
RA Turner G., de Vries R.P., Albang R., Albermann K., Andersen M.R.,
RA Bendtsen J.D., Benen J.A., van den Berg M., Breestraat S., Caddick M.X.,
RA Contreras R., Cornell M., Coutinho P.M., Danchin E.G., Debets A.J.,
RA Dekker P., van Dijck P.W., van Dijk A., Dijkhuizen L., Driessen A.J.,
RA d'Enfert C., Geysens S., Goosen C., Groot G.S., de Groot P.W.,
RA Guillemette T., Henrissat B., Herweijer M., van den Hombergh J.P.,
RA van den Hondel C.A., van der Heijden R.T., van der Kaaij R.M., Klis F.M.,
RA Kools H.J., Kubicek C.P., van Kuyk P.A., Lauber J., Lu X.,
RA van der Maarel M.J., Meulenberg R., Menke H., Mortimer M.A., Nielsen J.,
RA Oliver S.G., Olsthoorn M., Pal K., van Peij N.N., Ram A.F., Rinas U.,
RA Roubos J.A., Sagt C.M., Schmoll M., Sun J., Ussery D., Varga J.,
RA Vervecken W., van de Vondervoort P.J., Wedler H., Wosten H.A., Zeng A.P.,
RA van Ooyen A.J., Visser J., Stam H.;
RT "Genome sequencing and analysis of the versatile cell factory Aspergillus
RT niger CBS 513.88.";
RL Nat. Biotechnol. 25:221-231(2007).
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DR EMBL; AM269996; CAK96296.1; -; Genomic_DNA.
DR RefSeq; XP_001399219.1; XM_001399182.2.
DR AlphaFoldDB; A2QBP9; -.
DR EnsemblFungi; CAK96296; CAK96296; An02g00810.
DR GeneID; 4978562; -.
DR KEGG; ang:An02g00810; -.
DR VEuPathDB; FungiDB:An02g00810; -.
DR HOGENOM; CLU_005533_5_0_1; -.
DR OrthoDB; 1067404at2759; -.
DR Proteomes; UP000006706; Chromosome 4R.
DR GO; GO:0047145; F:demethylsterigmatocystin 6-O-methyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0044550; P:secondary metabolite biosynthetic process; IEA:UniProt.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR016461; COMT-like.
DR InterPro; IPR001077; O_MeTrfase_dom.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR43712:SF11; O-METHYLTRANSFERASE (AFU_ORTHOLOGUE AFUA_2G17820)-RELATED; 1.
DR PANTHER; PTHR43712; PUTATIVE (AFU_ORTHOLOGUE AFUA_4G14580)-RELATED; 1.
DR Pfam; PF00891; Methyltransf_2; 1.
DR PIRSF; PIRSF005739; O-mtase; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51683; SAM_OMT_II; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:CAK96296.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000006706};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000313|EMBL:CAK96296.1}.
FT DOMAIN 175..371
FT /note="O-methyltransferase"
FT /evidence="ECO:0000259|Pfam:PF00891"
FT ACT_SITE 301
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR005739-1"
SQ SEQUENCE 401 AA; 45215 MW; A7A69D13B5F8EA26 CRC64;
MAVDQSKVLS LVETIKQTAL QDQGACQSAQ SHFQLLGLID ELRLAVETPT ETVLRLIYQP
PQNAALRTVM DLGIFPLLVE HSKRGLSATE LAAQTGAERG LIVRLMRVMT ALGLCANHES
EVYTANDKTV ALTQPIGRDG IPCIYDLTLP TLAKLPDYFR EHRYTSPKEY SRSPMQWAVG
KSQFEWLAQH KHRQALFNSY MSSRRHGKPT WFDVYPVERL TNDAMDHRDA AFLVDVGGNQ
GHDLVKFHDR HPEVPGRLIL QDLPKVVSRC PGGRVEGMGY SFLDPQPIKG ARAYYFRAIF
HDWPDHICRK ILVNTISAMD PEYSRIIIVD FVLPDTNAPL LQSSLDIQMM SIGSGVERSE
RQWRELLDEV GLEITGIWNN NPGMESVIEA VPKQEQRCSS P
//
