ID   A2QQR7_ASPNC            Unreviewed;       881 AA.
AC   A2QQR7;
DT   06-MAR-2007, integrated into UniProtKB/TrEMBL.
DT   06-MAR-2007, sequence version 1.
DT   27-MAR-2024, entry version 82.
DE   SubName: Full=Contig An08c0100, genomic contig {ECO:0000313|EMBL:CAK45383.1};
GN   ORFNames=An08g03470 {ECO:0000313|EMBL:CAK45383.1};
OS   Aspergillus niger (strain ATCC MYA-4892 / CBS 513.88 / FGSC A1513).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Circumdati.
OX   NCBI_TaxID=425011 {ECO:0000313|EMBL:CAK45383.1, ECO:0000313|Proteomes:UP000006706};
RN   [1] {ECO:0000313|EMBL:CAK45383.1, ECO:0000313|Proteomes:UP000006706}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 513.88 / FGSC A1513 / ATCC MYA-4892
RC   {ECO:0000313|Proteomes:UP000006706};
RX   PubMed=17259976; DOI=10.1038/nbt1282;
RA   Pel H.J., de Winde J.H., Archer D.B., Dyer P.S., Hofmann G., Schaap P.J.,
RA   Turner G., de Vries R.P., Albang R., Albermann K., Andersen M.R.,
RA   Bendtsen J.D., Benen J.A., van den Berg M., Breestraat S., Caddick M.X.,
RA   Contreras R., Cornell M., Coutinho P.M., Danchin E.G., Debets A.J.,
RA   Dekker P., van Dijck P.W., van Dijk A., Dijkhuizen L., Driessen A.J.,
RA   d'Enfert C., Geysens S., Goosen C., Groot G.S., de Groot P.W.,
RA   Guillemette T., Henrissat B., Herweijer M., van den Hombergh J.P.,
RA   van den Hondel C.A., van der Heijden R.T., van der Kaaij R.M., Klis F.M.,
RA   Kools H.J., Kubicek C.P., van Kuyk P.A., Lauber J., Lu X.,
RA   van der Maarel M.J., Meulenberg R., Menke H., Mortimer M.A., Nielsen J.,
RA   Oliver S.G., Olsthoorn M., Pal K., van Peij N.N., Ram A.F., Rinas U.,
RA   Roubos J.A., Sagt C.M., Schmoll M., Sun J., Ussery D., Varga J.,
RA   Vervecken W., van de Vondervoort P.J., Wedler H., Wosten H.A., Zeng A.P.,
RA   van Ooyen A.J., Visser J., Stam H.;
RT   "Genome sequencing and analysis of the versatile cell factory Aspergillus
RT   niger CBS 513.88.";
RL   Nat. Biotechnol. 25:221-231(2007).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AM270165; CAK45383.1; -; Genomic_DNA.
DR   AlphaFoldDB; A2QQR7; -.
DR   EnsemblFungi; CAK45383; CAK45383; An08g03470.
DR   VEuPathDB; FungiDB:An08g03470; -.
DR   HOGENOM; CLU_002472_8_0_1; -.
DR   Proteomes; UP000006706; Chromosome 8R.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR   GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR   GO; GO:0007127; P:meiosis I; IEA:UniProt.
DR   GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR   CDD; cd03281; ABC_MSH5_euk; 1.
DR   Gene3D; 1.10.1420.10; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR000432; DNA_mismatch_repair_MutS_C.
DR   InterPro; IPR007696; DNA_mismatch_repair_MutS_core.
DR   InterPro; IPR036187; DNA_mismatch_repair_MutS_sf.
DR   InterPro; IPR045076; MutS_family.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR11361; DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER; 1.
DR   PANTHER; PTHR11361:SF20; MUTS PROTEIN HOMOLOG 5; 1.
DR   Pfam; PF05192; MutS_III; 1.
DR   Pfam; PF00488; MutS_V; 1.
DR   SMART; SM00534; MUTSac; 1.
DR   SMART; SM00533; MUTSd; 1.
DR   SUPFAM; SSF48334; DNA repair protein MutS, domain III; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS00486; DNA_MISMATCH_REPAIR_2; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006706}.
FT   DOMAIN          702..718
FT                   /note="DNA mismatch repair proteins mutS family"
FT                   /evidence="ECO:0000259|PROSITE:PS00486"
FT   REGION          1..53
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        33..53
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   881 AA;  98662 MW;  5B1D78452CBEEAE6 CRC64;
     MEPQTKRKRT TYPSHFESFN TWSNHDDRPK SRFSSNLPPT SQETLRARAS TSNDTELYRS
     GSGLFEHAVD DELEQVVVAV DVRDSGTVGC SYYSALEEKL YLLGDLRYST KEIIDSYTLS
     YVPYQLEVRP SQEFNFSNAK NRLIALDLSS RHEHRIKFLV PHSGLVDGEQ MDAENLDLTL
     QEGKLLNVYG SVDMENTVTI GCAGVILAYL QRRRASMSIS NERALGILRV SSVEMFALTG
     TMFVNGRTLF SLQIMESESH PSMVNHGPGR KSTSSKEGLS VYGLFQRFAC TPQGRNQLKQ
     MFLRPSVELD VINERNSFIG VYLRTDNFNP FDKMVKGLKH IKNLHYVMIN LRKGISTGSG
     KIMGFKATVW ATLLAALRAF EAAQLYKVGR MIQETKVDID SSEEQGRTVV KPGIDRDLDR
     IKDRYDGLNS LLKQVAIEIA TTIPESYDID VNVVYFPQLG FNIAIPLNNA RDAAYRGAEN
     EWELMFFTEN RAYLKDFRMR EMDDKLGDIY GIICEREIEI VYDLAQRVLQ YEEVLLEASD
     ICGQIDSLLA MAHAASSYKL VRPKMVQEDV IKIKGGRHIL QELTVSSYVP NDTYLIGRRT
     QRESVEPICT TLKPYENDCE PSMLLLTGPN YSGKSVYMKQ VALIIYLAQV GSFVPAESAE
     LGIIDKILVK SNTQDSVSQI QSTFMNDLQQ LSFDLKQVTG HSLLLIDEFG KGTNEYDGIG
     LACGVLENLL NREDAPKVIA ATHFHEILAN GYLKPRPQLQ LGHMEVRVHE EPGEAEDQIT
     YLYNFRLGRS DQSFGTICAA MNGISQTIVD RANEIAALSA RGENLIAACA VLSAQETQAL
     EDAVGYMLSV CFWSSVEIAN GVLLEGQISK RVPVVGSVRG L
//