ID A2R027_ASPNC Unreviewed; 337 AA.
AC A2R027;
DT 06-MAR-2007, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2007, sequence version 1.
DT 27-MAR-2024, entry version 74.
DE SubName: Full=Contig An12c0220, genomic contig {ECO:0000313|EMBL:CAK46341.1};
GN ORFNames=An12g07130 {ECO:0000313|EMBL:CAK46341.1};
OS Aspergillus niger (strain ATCC MYA-4892 / CBS 513.88 / FGSC A1513).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Circumdati.
OX NCBI_TaxID=425011 {ECO:0000313|EMBL:CAK46341.1, ECO:0000313|Proteomes:UP000006706};
RN [1] {ECO:0000313|EMBL:CAK46341.1, ECO:0000313|Proteomes:UP000006706}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 513.88 / FGSC A1513 / ATCC MYA-4892
RC {ECO:0000313|Proteomes:UP000006706};
RX PubMed=17259976; DOI=10.1038/nbt1282;
RA Pel H.J., de Winde J.H., Archer D.B., Dyer P.S., Hofmann G., Schaap P.J.,
RA Turner G., de Vries R.P., Albang R., Albermann K., Andersen M.R.,
RA Bendtsen J.D., Benen J.A., van den Berg M., Breestraat S., Caddick M.X.,
RA Contreras R., Cornell M., Coutinho P.M., Danchin E.G., Debets A.J.,
RA Dekker P., van Dijck P.W., van Dijk A., Dijkhuizen L., Driessen A.J.,
RA d'Enfert C., Geysens S., Goosen C., Groot G.S., de Groot P.W.,
RA Guillemette T., Henrissat B., Herweijer M., van den Hombergh J.P.,
RA van den Hondel C.A., van der Heijden R.T., van der Kaaij R.M., Klis F.M.,
RA Kools H.J., Kubicek C.P., van Kuyk P.A., Lauber J., Lu X.,
RA van der Maarel M.J., Meulenberg R., Menke H., Mortimer M.A., Nielsen J.,
RA Oliver S.G., Olsthoorn M., Pal K., van Peij N.N., Ram A.F., Rinas U.,
RA Roubos J.A., Sagt C.M., Schmoll M., Sun J., Ussery D., Varga J.,
RA Vervecken W., van de Vondervoort P.J., Wedler H., Wosten H.A., Zeng A.P.,
RA van Ooyen A.J., Visser J., Stam H.;
RT "Genome sequencing and analysis of the versatile cell factory Aspergillus
RT niger CBS 513.88.";
RL Nat. Biotechnol. 25:221-231(2007).
CC -!- SIMILARITY: Belongs to the NmrA-type oxidoreductase family. Isoflavone
CC reductase subfamily. {ECO:0000256|ARBA:ARBA00005725}.
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DR EMBL; AM270278; CAK46341.1; -; Genomic_DNA.
DR RefSeq; XP_001395766.1; XM_001395729.1.
DR AlphaFoldDB; A2R027; -.
DR EnsemblFungi; CAK46341; CAK46341; An12g07130.
DR GeneID; 4986062; -.
DR KEGG; ang:An12g07130; -.
DR VEuPathDB; FungiDB:An12g07130; -.
DR HOGENOM; CLU_044876_1_1_1; -.
DR OrthoDB; 2166478at2759; -.
DR Proteomes; UP000006706; Chromosome 3L.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR CDD; cd05259; PCBER_SDR_a; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR Gene3D; 3.90.25.10; UDP-galactose 4-epimerase, domain 1; 1.
DR InterPro; IPR016040; NAD(P)-bd_dom.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR045312; PCBER-like.
DR PANTHER; PTHR47706:SF7; NMRA-LIKE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR47706; NMRA-LIKE FAMILY PROTEIN; 1.
DR Pfam; PF13460; NAD_binding_10; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000006706}.
FT DOMAIN 23..156
FT /note="NAD(P)-binding"
FT /evidence="ECO:0000259|Pfam:PF13460"
SQ SEQUENCE 337 AA; 36863 MW; 716392AEFE983F3A CRC64;
MAKYAKDQPA GFKNSIERVA IVGAGGTVGL NIVTELLKTG KHTVTALTRA DSTNKIPEGV
QIAHINYDDE ATIISALKGQ QFLIITMAPT APRDTHSKIV QAAAKAGIPY VMPNGYGGDI
EKVKLGEETF LGPVNRAHRD EIARLGMQWI TVCCGFWYDY SLAGGESRFG FDFDKRSLTI
YDDGTTKNST STLSQIGRAV AKVLSLKELP EDESDKSLTL SSFLNKGIYF QSFLVNQKEM
FESVKRVTGT TDADWTITHE STKKRYEEGL ALVKGGNMAG FAKMLYARGF YPEDTSDHAS
KAQNELLGLP EESLDEGTKA AIDLVKKLQA RPERMAS
//
