ID A2RAI7_ASPNC Unreviewed; 616 AA.
AC A2RAI7;
DT 06-MAR-2007, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2007, sequence version 1.
DT 27-MAR-2024, entry version 79.
DE SubName: Full=Contig An18c0100, genomic contig {ECO:0000313|EMBL:CAK48713.1};
DE EC=3.1.3.16 {ECO:0000313|EMBL:CAK48713.1};
GN ORFNames=An18g03290 {ECO:0000313|EMBL:CAK48713.1};
OS Aspergillus niger (strain ATCC MYA-4892 / CBS 513.88 / FGSC A1513).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Circumdati.
OX NCBI_TaxID=425011 {ECO:0000313|EMBL:CAK48713.1, ECO:0000313|Proteomes:UP000006706};
RN [1] {ECO:0000313|EMBL:CAK48713.1, ECO:0000313|Proteomes:UP000006706}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 513.88 / FGSC A1513 / ATCC MYA-4892
RC {ECO:0000313|Proteomes:UP000006706};
RX PubMed=17259976; DOI=10.1038/nbt1282;
RA Pel H.J., de Winde J.H., Archer D.B., Dyer P.S., Hofmann G., Schaap P.J.,
RA Turner G., de Vries R.P., Albang R., Albermann K., Andersen M.R.,
RA Bendtsen J.D., Benen J.A., van den Berg M., Breestraat S., Caddick M.X.,
RA Contreras R., Cornell M., Coutinho P.M., Danchin E.G., Debets A.J.,
RA Dekker P., van Dijck P.W., van Dijk A., Dijkhuizen L., Driessen A.J.,
RA d'Enfert C., Geysens S., Goosen C., Groot G.S., de Groot P.W.,
RA Guillemette T., Henrissat B., Herweijer M., van den Hombergh J.P.,
RA van den Hondel C.A., van der Heijden R.T., van der Kaaij R.M., Klis F.M.,
RA Kools H.J., Kubicek C.P., van Kuyk P.A., Lauber J., Lu X.,
RA van der Maarel M.J., Meulenberg R., Menke H., Mortimer M.A., Nielsen J.,
RA Oliver S.G., Olsthoorn M., Pal K., van Peij N.N., Ram A.F., Rinas U.,
RA Roubos J.A., Sagt C.M., Schmoll M., Sun J., Ussery D., Varga J.,
RA Vervecken W., van de Vondervoort P.J., Wedler H., Wosten H.A., Zeng A.P.,
RA van Ooyen A.J., Visser J., Stam H.;
RT "Genome sequencing and analysis of the versatile cell factory Aspergillus
RT niger CBS 513.88.";
RL Nat. Biotechnol. 25:221-231(2007).
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DR EMBL; AM270402; CAK48713.1; -; Genomic_DNA.
DR RefSeq; XP_001398789.1; XM_001398752.2.
DR AlphaFoldDB; A2RAI7; -.
DR SMR; A2RAI7; -.
DR EnsemblFungi; CAK48713; CAK48713; An18g03290.
DR GeneID; 4989891; -.
DR KEGG; ang:An18g03290; -.
DR VEuPathDB; FungiDB:An18g03290; -.
DR HOGENOM; CLU_015533_2_1_1; -.
DR OrthoDB; 759105at2759; -.
DR Proteomes; UP000006706; Chromosome 8L.
DR GO; GO:0005935; C:cellular bud neck; IEA:EnsemblFungi.
DR GO; GO:0005934; C:cellular bud tip; IEA:EnsemblFungi.
DR GO; GO:0000775; C:chromosome, centromeric region; IEA:EnsemblFungi.
DR GO; GO:0090443; C:FAR/SIN/STRIPAK complex; IEA:EnsemblFungi.
DR GO; GO:0043332; C:mating projection tip; IEA:EnsemblFungi.
DR GO; GO:0110085; C:mitotic actomyosin contractile ring; IEA:EnsemblFungi.
DR GO; GO:0005634; C:nucleus; IEA:EnsemblFungi.
DR GO; GO:0000159; C:protein phosphatase type 2A complex; IEA:EnsemblFungi.
DR GO; GO:0005816; C:spindle pole body; IEA:EnsemblFungi.
DR GO; GO:0017018; F:myosin phosphatase activity; IEA:UniProtKB-EC.
DR GO; GO:0061509; P:asymmetric protein localization to old mitotic spindle pole body; IEA:EnsemblFungi.
DR GO; GO:0030952; P:establishment or maintenance of cytoskeleton polarity; IEA:EnsemblFungi.
DR GO; GO:1990813; P:meiotic centromeric cohesion protection in anaphase I; IEA:EnsemblFungi.
DR GO; GO:0007094; P:mitotic spindle assembly checkpoint signaling; IEA:EnsemblFungi.
DR GO; GO:0031030; P:negative regulation of septation initiation signaling; IEA:EnsemblFungi.
DR GO; GO:0006417; P:regulation of translation; IEA:EnsemblFungi.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR021133; HEAT_type_2.
DR PANTHER; PTHR10648:SF4; PROTEIN PHOSPHATASE 2 (FORMERLY 2A), REGULATORY SUBUNIT A, BETA ISOFORM-RELATED; 1.
DR PANTHER; PTHR10648; SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A 65 KDA REGULATORY SUBUNIT; 1.
DR Pfam; PF13646; HEAT_2; 1.
DR Pfam; PF20168; PDS5; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS50077; HEAT_REPEAT; 10.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:CAK48713.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000006706}.
FT REPEAT 12..50
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT REPEAT 89..127
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT REPEAT 205..243
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT REPEAT 246..284
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT REPEAT 285..323
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT REPEAT 324..362
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT REPEAT 363..401
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT REPEAT 402..440
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT REPEAT 519..557
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT REPEAT 582..616
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
SQ SEQUENCE 616 AA; 69140 MW; FCC3360D19EEE200 CRC64;
MEGQGENDEL YPIAVLIDEL KHDDVLLRLN AIHRLSTIAL ALGPERTREE LIPFLDDSVE
DEDEVLTALS EELGNFIEYV GGPEYGHVLL SPLENLAAIE EPLVREKAVE SLNKIGEQLS
EKQIEENFIP MVLRLSKADW FTSKVSATGL YCVPYRKASP SSQQTLRQYY GGLVHDDTPM
VRRQSGNNLA KFIKELNTQI VIDEMIPLFQ HLATDEQDSV RLLTVDVLIS IAEEIPKEQQ
PSHGVLLTSL RNLFEDKSWR VRYMVADRYE KIAKAVHEEV VTRDMVPSFV KLLKDTEAEV
RTAIAGQIPG FCNLIDRDTL LNEIMTSVED LVSDPSQHVR AALGTQISGL APILGKEETI
AHLLPMFLQM LKDEFPDVRL HIISKLELVN KVIGIDLLSQ SLLPAIVQLA EDKQWRVRLA
IIEYIPLLAS QLGVKFFDEQ LSELCMGWLG DTVFSIREAA TQNLRKLTEV FGVDWAKGSI
IPKVMGMGQH TNYLYRMTTC FAISTLAPVV SLDIIENSIL PILDRLVSDE IPNIRFNVAK
SYAVLIDTLR RLPTEGTLTD LEKAGKTATP SPRGQDLIQQ RILPSLEKLQ EDEDVDVRYF
ATTAAGGHEE VMQTSP
//
