ID A2SE74_METPP Unreviewed; 327 AA.
AC A2SE74;
DT 06-MAR-2007, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2007, sequence version 1.
DT 27-MAR-2024, entry version 90.
DE SubName: Full=Alcohol dehydrogenase {ECO:0000313|EMBL:ABM93863.1};
GN OrderedLocusNames=Mpe_A0901 {ECO:0000313|EMBL:ABM93863.1};
OS Methylibium petroleiphilum (strain ATCC BAA-1232 / LMG 22953 / PM1).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Sphaerotilaceae; Methylibium.
OX NCBI_TaxID=420662 {ECO:0000313|EMBL:ABM93863.1, ECO:0000313|Proteomes:UP000000366};
RN [1] {ECO:0000313|EMBL:ABM93863.1, ECO:0000313|Proteomes:UP000000366}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-1232 / LMG 22953 / PM1
RC {ECO:0000313|Proteomes:UP000000366};
RX PubMed=17158667; DOI=10.1128/JB.01259-06;
RA Kane S.R., Chakicherla A.Y., Chain P.S.G., Schmidt R., Shin M.W.,
RA Legler T.C., Scow K.M., Larimer F.W., Lucas S.M., Richardson P.M.,
RA Hristova K.R.;
RT "Whole-genome analysis of the methyl tert-butyl ether-degrading beta-
RT proteobacterium Methylibium petroleiphilum PM1.";
RL J. Bacteriol. 189:1931-1945(2007).
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DR EMBL; CP000555; ABM93863.1; -; Genomic_DNA.
DR RefSeq; WP_011828501.1; NC_008825.1.
DR AlphaFoldDB; A2SE74; -.
DR STRING; 420662.Mpe_A0901; -.
DR KEGG; mpt:Mpe_A0901; -.
DR eggNOG; COG0604; Bacteria.
DR HOGENOM; CLU_026673_26_3_4; -.
DR Proteomes; UP000000366; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR CDD; cd08288; MDR_yhdh; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR014188; Acrylyl-CoA_reductase_AcuI.
DR InterPro; IPR013149; ADH-like_C.
DR InterPro; IPR013154; ADH-like_N.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020843; PKS_ER.
DR NCBIfam; TIGR02823; oxido_YhdH; 1.
DR PANTHER; PTHR43677:SF1; ACRYLYL-COA REDUCTASE ACUI-RELATED; 1.
DR PANTHER; PTHR43677; SHORT-CHAIN DEHYDROGENASE/REDUCTASE; 1.
DR Pfam; PF08240; ADH_N; 1.
DR Pfam; PF00107; ADH_zinc_N; 1.
DR SMART; SM00829; PKS_ER; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000000366};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 122..139
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 151..173
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 13..323
FT /note="Enoyl reductase (ER)"
FT /evidence="ECO:0000259|SMART:SM00829"
SQ SEQUENCE 327 AA; 34697 MW; 20AF2123E9ED0748 CRC64;
MFRALMLTQV DRRTHAELVE LDESQLPPGD VTVRIEYSSL NFKDALAVTG RGAVVKNWPL
VPGIDLAGVV ERSSDPAWQP GDRVVVNGWG LGETEWGGLA QKARLSPQCL LRLPAAFTTR
EAMAIATAGY TAALCVIALQ RHGLEPGADE VLVTGAAGGV GSVAVALLAG LGFRVVASTG
RPAEAEYLRF LGAAAILDRA ELSSPGKPLQ SERWAGVVDT VGSHTLVNAC AQTQWHGAVT
ACGLAQGSDL PGTVMPFILR GITLYGINCM RVDEATRRLA WELLAQHVRS DQLAQMTQEI
GLSEVIAYSP GLLDGKVRGR TVVDVNR
//
