ID A2SFJ7_METPP Unreviewed; 1353 AA.
AC A2SFJ7;
DT 06-MAR-2007, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2007, sequence version 1.
DT 27-MAR-2024, entry version 104.
DE SubName: Full=ATP-dependent helicase HrpA {ECO:0000313|EMBL:ABM94336.1};
GN OrderedLocusNames=Mpe_A1374 {ECO:0000313|EMBL:ABM94336.1};
OS Methylibium petroleiphilum (strain ATCC BAA-1232 / LMG 22953 / PM1).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Sphaerotilaceae; Methylibium.
OX NCBI_TaxID=420662 {ECO:0000313|EMBL:ABM94336.1, ECO:0000313|Proteomes:UP000000366};
RN [1] {ECO:0000313|EMBL:ABM94336.1, ECO:0000313|Proteomes:UP000000366}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-1232 / LMG 22953 / PM1
RC {ECO:0000313|Proteomes:UP000000366};
RX PubMed=17158667; DOI=10.1128/JB.01259-06;
RA Kane S.R., Chakicherla A.Y., Chain P.S.G., Schmidt R., Shin M.W.,
RA Legler T.C., Scow K.M., Larimer F.W., Lucas S.M., Richardson P.M.,
RA Hristova K.R.;
RT "Whole-genome analysis of the methyl tert-butyl ether-degrading beta-
RT proteobacterium Methylibium petroleiphilum PM1.";
RL J. Bacteriol. 189:1931-1945(2007).
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DR EMBL; CP000555; ABM94336.1; -; Genomic_DNA.
DR RefSeq; WP_011828973.1; NC_008825.1.
DR STRING; 420662.Mpe_A1374; -.
DR KEGG; mpt:Mpe_A1374; -.
DR eggNOG; COG1643; Bacteria.
DR HOGENOM; CLU_001832_3_3_4; -.
DR Proteomes; UP000000366; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0003724; F:RNA helicase activity; IEA:InterPro.
DR CDD; cd18791; SF2_C_RHA; 1.
DR Gene3D; 1.20.120.1080; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR007502; Helicase-assoc_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR024590; HrpA_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR010222; RNA_helicase_HrpA.
DR NCBIfam; TIGR01967; DEAH_box_HrpA; 1.
DR PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR PANTHER; PTHR18934:SF83; PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE DHX16; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF11898; DUF3418; 1.
DR Pfam; PF21010; HA2_C; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF07717; OB_NTP_bind; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00847; HA2; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000313|EMBL:ABM94336.1};
KW Hydrolase {ECO:0000313|EMBL:ABM94336.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000000366}.
FT DOMAIN 36..207
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 263..436
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 198..224
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 560..591
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1028..1076
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1030..1049
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1353 AA; 150356 MW; 2F312D9BD629880B CRC64;
MPETAPRTAA PAPPRSLPPI RFPEALPVSA RRDEIAEAVQ RHQVVIVCGE TGSGKTTQLP
KLMLALGRGK ANAKPGERGR LIGHTQPRRI AASSVAKRIA DELETPLGEV VGYKVRFQDR
LTSGASVKLM TDGILLAETQ TDPLLQAYDT LIIDEAHERS LNIDFLLGYL RQILPKRPDL
KVIVTSATID ADRFARHFGS VRPTPDRPKP GGAPSGGGDS AERGAWGHEL VPAPVIQVSG
RLFPVEQRWR AFEESREHDL NDAIADAVDE LWREGRGDVL VFLPGEREIR EAADHLRKHL
LQQHRGGPQP EILPLFARLS QTEQDRVFQA GNGRRIVLAT NVAETSLTVP GIRYVVDAGT
ARVKRYSYRN KVEQLQVEPI SQAAANQRAG RCGRVADGIC IRLYDEKDYA GRPRFTDPEI
LRSSLAGVIL RMKALGLGDV EAFPFLEPPP KKAIADGYAL LNELGATDDD NALTAIGKEL
ARLPLDPRIG RMILAARDRQ ALAEVLVIAS ALSVQDVRDR PLEQQQAADQ KHKLFDDERS
EFVGYLKLWQ WIEAGRGHAA HPSAMPAPAR APDGRGEGTA AHKLSNRQQE QRLREHFVSP
RRVREWRDIH SQLHTVVAEH GWRLNGTPAT YEQLHLAMLA GLLGNVGCKS DDEDWYLGAR
GIKFWRHPGA HLSKKPGRWL IAAELVETTR LFGRALAAIE PAWIVQVAGH LLKKQLLEPH
WEKKAAEVVA LERATLYGLV VYNNKRVNFG NVDPAAAREI FIREALVNGE WESRLPFLAH
NRKLIRQVEE LEHKSRRQDV LVDDELIFAF YDQQLPKDVH SGTTLERWYR AQSPQQPKLL
MLTKDELMRH EAAGITTAAF PKTLRLGGID CEATYLHEPG DSKDGLTVTV PIYALNQVND
ERCEWLVPGL LKDKVLALMK SLHQRPRSRL VPLPEAAAEF CELVPFAQGG LVDALLKAVR
ERTQIAVQRN DFKLETLQPH LFMNFRVVDE HGRQLGMGRH LPTLKAELGA QARSAFQALA
ALKLGGVEQA ANSPSPQPSP TSGRGNRTNS LPLPPAGEGR GEGTPPSATP PQRHTTWSFG
ELPELMEIRR GAQSLVGFPA LIDKGGHVEI EVFDEPDVAA TRHRAGLRRL VALQIKEPLK
YLEKSIPDLP RMAVAYMALG GSADELRAQI IDVALDRAFL VEPLPTDAAG FAKRIDEGRT
RLNLIAQEVA RLAATVLAEQ ATATRKLKDT RPAKEVADDV AAQLARLCPK RFLAETGYAQ
LHHLPRYLKG VTLRLDKWRA DPARDAARLA ELRPIEQRYL RRVAELKGAA DARLDEFRWL
IEELRVSLFA QELRTPQPVS AKRLEKAWSQ LSA
//
