ID A2SHR2_METPP Unreviewed; 341 AA.
AC A2SHR2;
DT 06-MAR-2007, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2007, sequence version 1.
DT 27-MAR-2024, entry version 89.
DE SubName: Full=Zinc-containing alcohol dehydrogenase superfamily {ECO:0000313|EMBL:ABM95101.1};
GN OrderedLocusNames=Mpe_A2145 {ECO:0000313|EMBL:ABM95101.1};
OS Methylibium petroleiphilum (strain ATCC BAA-1232 / LMG 22953 / PM1).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Sphaerotilaceae; Methylibium.
OX NCBI_TaxID=420662 {ECO:0000313|EMBL:ABM95101.1, ECO:0000313|Proteomes:UP000000366};
RN [1] {ECO:0000313|EMBL:ABM95101.1, ECO:0000313|Proteomes:UP000000366}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-1232 / LMG 22953 / PM1
RC {ECO:0000313|Proteomes:UP000000366};
RX PubMed=17158667; DOI=10.1128/JB.01259-06;
RA Kane S.R., Chakicherla A.Y., Chain P.S.G., Schmidt R., Shin M.W.,
RA Legler T.C., Scow K.M., Larimer F.W., Lucas S.M., Richardson P.M.,
RA Hristova K.R.;
RT "Whole-genome analysis of the methyl tert-butyl ether-degrading beta-
RT proteobacterium Methylibium petroleiphilum PM1.";
RL J. Bacteriol. 189:1931-1945(2007).
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DR EMBL; CP000555; ABM95101.1; -; Genomic_DNA.
DR AlphaFoldDB; A2SHR2; -.
DR STRING; 420662.Mpe_A2145; -.
DR KEGG; mpt:Mpe_A2145; -.
DR eggNOG; COG2130; Bacteria.
DR HOGENOM; CLU_026673_29_2_4; -.
DR Proteomes; UP000000366; Chromosome.
DR GO; GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR CDD; cd05288; PGDH; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013149; ADH-like_C.
DR InterPro; IPR041694; ADH_N_2.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR045010; MDR_fam.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020843; PKS_ER.
DR PANTHER; PTHR43205; PROSTAGLANDIN REDUCTASE; 1.
DR PANTHER; PTHR43205:SF7; PROSTAGLANDIN REDUCTASE 1; 1.
DR Pfam; PF16884; ADH_N_2; 1.
DR Pfam; PF00107; ADH_zinc_N; 1.
DR SMART; SM00829; PKS_ER; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000000366}.
FT DOMAIN 17..332
FT /note="Enoyl reductase (ER)"
FT /evidence="ECO:0000259|SMART:SM00829"
SQ SEQUENCE 341 AA; 36557 MW; CB4E4FF13266F22B CRC64;
MTTAGNRQLL LARHPEGRIR DEDFRLVDAP LAPLADGQVQ VRTIYLSIDP TMRVWLHPTD
NYLPMIQPGE VFRGIGIGVV EATRHPGFAQ GTLVQGLFGC QQRVISDGSD LLVLSDIAPL
PVTAHFSLLG HIGMTAYCGL VKVGAAKAGE TLLVSGAAGA VGALVGQIGR ILGCRVVGVA
GGAEKCRYLT EVLGFDAAVD YRAADFDASL AAACSKGIDV YFDNVGGHTL ELALGLMNDF
GRIVCCGMIS TYNDYDVPGP RNIVQVVLKR LRMQGFVILD PEHDPKEAYA HLLQWAGEGR
LQHRAHVVEG LERVPDAINM LLDGRNQGKL MVRLSDEPAA A
//
