ID A2SJ79_METPP Unreviewed; 1063 AA.
AC A2SJ79;
DT 06-MAR-2007, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2007, sequence version 1.
DT 27-MAR-2024, entry version 93.
DE SubName: Full=Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(S) {ECO:0000313|EMBL:ABM95618.1};
GN OrderedLocusNames=Mpe_A2664 {ECO:0000313|EMBL:ABM95618.1};
OS Methylibium petroleiphilum (strain ATCC BAA-1232 / LMG 22953 / PM1).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Sphaerotilaceae; Methylibium.
OX NCBI_TaxID=420662 {ECO:0000313|EMBL:ABM95618.1, ECO:0000313|Proteomes:UP000000366};
RN [1] {ECO:0000313|EMBL:ABM95618.1, ECO:0000313|Proteomes:UP000000366}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-1232 / LMG 22953 / PM1
RC {ECO:0000313|Proteomes:UP000000366};
RX PubMed=17158667; DOI=10.1128/JB.01259-06;
RA Kane S.R., Chakicherla A.Y., Chain P.S.G., Schmidt R., Shin M.W.,
RA Legler T.C., Scow K.M., Larimer F.W., Lucas S.M., Richardson P.M.,
RA Hristova K.R.;
RT "Whole-genome analysis of the methyl tert-butyl ether-degrading beta-
RT proteobacterium Methylibium petroleiphilum PM1.";
RL J. Bacteriol. 189:1931-1945(2007).
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DR EMBL; CP000555; ABM95618.1; -; Genomic_DNA.
DR RefSeq; WP_011830248.1; NC_008825.1.
DR AlphaFoldDB; A2SJ79; -.
DR STRING; 420662.Mpe_A2664; -.
DR KEGG; mpt:Mpe_A2664; -.
DR eggNOG; COG5000; Bacteria.
DR eggNOG; COG5001; Bacteria.
DR HOGENOM; CLU_000445_70_8_4; -.
DR Proteomes; UP000000366; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd06225; HAMP; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR44757:SF2; BIOFILM ARCHITECTURE MAINTENANCE PROTEIN MBAA; 1.
DR PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF13426; PAS_9; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00304; HAMP; 1.
DR SMART; SM00086; PAC; 1.
DR SMART; SM00091; PAS; 2.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50885; HAMP; 1.
DR PROSITE; PS50113; PAC; 1.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000000366};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 20..40
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 302..323
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 324..377
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 501..546
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 574..626
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 658..792
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 801..1055
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
SQ SEQUENCE 1063 AA; 116396 MW; C2F84C4B64A73D62 CRC64;
MTISHPFSRL LARLSVGRKL MLIYLLDLTA VIFVSSILIN EKFIAIDFAR KEIAGNAYIA
GMRDGLIEAA LGPDASGAAA RTDHRAALAL AERQHGAGMQ SEEPSLALAT AYGVLATAGP
GDRGKAQSDV LARGRDLITR VGNQSNLILD PDLDSYYTMS LIVLRYPELL ETIDGIGAQL
AAQVSAGAGL AEARTQYLIL EGKLDATRQG IDTDHSEAYA AGGPALKAQL RPAQAKLQAA
LEAYRRSARL LFDSGATPQS LAGVHVAQAG LVRELQVAWA VAGGAMDGLL DARVASLYHR
MWIHLGTALA LLCAILAIVY FVARQIAMPL RHLAEVTDTV RRTGDHSLRA QWSSSDEIGR
LVVGFNGMLA QLDQERETQK ELAASARAAE AQRALVEATP IPLVVTSVPG HEVLHANPPA
EAWLAGHRAD PWKHGLDSSV RARFFQQLAD RGAVDEFEVR WGAGTEPAWA VLSARRVRYQ
GQDAVLTAFA PINHLKLMER RLELWAKVFE ASSEGILIVD AQRRILTANQ AFSRHTGYEL
QEVVGEKPSL MLAVEQTDEQ SAAFWQSVSN RGTWQGELQV RRRNGSEYPA WLMVNAVRQS
QGDISHYIFT SIDISDRKKS EQRIRFLADH DVLTELPNRS LCTERLRMAV QQAQRSGQQV
AVMFIDLDRF KDINDSLGHH IGDGLLRSVA RRLLEAVRAG DTVSRLGGDE FVIVLNGVQH
IDEVTHIVDQ RLIPLIRQPH LVEGAELHVS CSVGIAVFPD DATDIDELMK HADTAMYQAK
AGGKDAAEFF TAEMTQRAES RMQLDADLRR ALELGQFELH WQPRVSAAGG VLLGVEGLLR
WQHPQRGLVS PAHFIPLAEE TGLIVPIGAW VIEEACRQVA AWRAQGLPSF GVSINLSARQ
LRDDGLTDLV RASLLRHGVP PGVLELELTE SMVMDDAERN LRQMHTLRDL GVGLAIDDFG
TGYSSLAYLN RFPIDKLKID RSFVHDMLAD PTDRAITMAI IGLGHALGLQ VVAEGVEEPR
AAALLREARC DELQGYLFGR PMPVPAFEAW LAEREAPVTR VTV
//
