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Database: UniProt
Entry: A2SSV9
LinkDB: A2SSV9
Original site: A2SSV9 
ID   RS4_METLZ               Reviewed;         181 AA.
AC   A2SSV9;
DT   10-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT   06-MAR-2007, sequence version 1.
DT   27-MAR-2024, entry version 83.
DE   RecName: Full=Small ribosomal subunit protein uS4 {ECO:0000255|HAMAP-Rule:MF_01306};
DE   AltName: Full=30S ribosomal protein S4 {ECO:0000305};
GN   Name=rps4 {ECO:0000255|HAMAP-Rule:MF_01306}; OrderedLocusNames=Mlab_1246;
OS   Methanocorpusculum labreanum (strain ATCC 43576 / DSM 4855 / Z).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC   Methanomicrobiales; Methanocorpusculaceae; Methanocorpusculum.
OX   NCBI_TaxID=410358;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43576 / DSM 4855 / Z;
RX   PubMed=21304657; DOI=10.4056/sigs.35575;
RA   Anderson I.J., Sieprawska-Lupa M., Goltsman E., Lapidus A., Copeland A.,
RA   Glavina Del Rio T., Tice H., Dalin E., Barry K., Pitluck S., Hauser L.,
RA   Land M., Lucas S., Richardson P., Whitman W.B., Kyrpides N.C.;
RT   "Complete genome sequence of Methanocorpusculum labreanum type strain Z.";
RL   Stand. Genomic Sci. 1:197-203(2009).
CC   -!- FUNCTION: One of the primary rRNA binding proteins, it binds directly
CC       to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
CC       {ECO:0000255|HAMAP-Rule:MF_01306}.
CC   -!- FUNCTION: With S5 and S12 plays an important role in translational
CC       accuracy. {ECO:0000255|HAMAP-Rule:MF_01306}.
CC   -!- SUBUNIT: Part of the 30S ribosomal subunit. Contacts protein S5. The
CC       interaction surface between S4 and S5 is involved in control of
CC       translational fidelity. {ECO:0000255|HAMAP-Rule:MF_01306}.
CC   -!- SIMILARITY: Belongs to the universal ribosomal protein uS4 family.
CC       {ECO:0000255|HAMAP-Rule:MF_01306}.
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DR   EMBL; CP000559; ABN07415.1; -; Genomic_DNA.
DR   RefSeq; WP_011833618.1; NC_008942.1.
DR   AlphaFoldDB; A2SSV9; -.
DR   SMR; A2SSV9; -.
DR   STRING; 410358.Mlab_1246; -.
DR   GeneID; 4795262; -.
DR   KEGG; mla:Mlab_1246; -.
DR   eggNOG; arCOG04239; Archaea.
DR   HOGENOM; CLU_089738_1_1_2; -.
DR   OrthoDB; 10429at2157; -.
DR   Proteomes; UP000000365; Chromosome.
DR   GO; GO:0015935; C:small ribosomal subunit; IEA:InterPro.
DR   GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0006412; P:translation; IEA:UniProtKB-UniRule.
DR   CDD; cd00165; S4; 1.
DR   Gene3D; 3.10.290.10; RNA-binding S4 domain; 1.
DR   HAMAP; MF_01306_A; Ribosomal_uS4_A; 1.
DR   InterPro; IPR022801; Ribosomal_uS4.
DR   InterPro; IPR022802; Ribosomal_uS4_arc.
DR   InterPro; IPR018079; Ribosomal_uS4_CS.
DR   InterPro; IPR005710; Ribosomal_uS4_euk/arc.
DR   InterPro; IPR001912; Ribosomal_uS4_N.
DR   InterPro; IPR002942; S4_RNA-bd.
DR   InterPro; IPR036986; S4_RNA-bd_sf.
DR   NCBIfam; TIGR01018; uS4_arch; 1.
DR   PANTHER; PTHR11831; 30S 40S RIBOSOMAL PROTEIN; 1.
DR   PANTHER; PTHR11831:SF5; 40S RIBOSOMAL PROTEIN S9; 1.
DR   Pfam; PF01479; S4; 1.
DR   SMART; SM01390; Ribosomal_S4; 1.
DR   SMART; SM00363; S4; 1.
DR   SUPFAM; SSF55174; Alpha-L RNA-binding motif; 1.
DR   PROSITE; PS00632; RIBOSOMAL_S4; 1.
DR   PROSITE; PS50889; S4; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Ribonucleoprotein; Ribosomal protein; RNA-binding;
KW   rRNA-binding.
FT   CHAIN           1..181
FT                   /note="Small ribosomal subunit protein uS4"
FT                   /id="PRO_0000293405"
FT   DOMAIN          108..180
FT                   /note="S4 RNA-binding"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01306"
SQ   SEQUENCE   181 AA;  20488 MW;  31701C9F6A583F45 CRC64;
     MGYPGKNTKQ YSSPKRRFEK SRIESERVLA ITYGLRNKRE IWRATEVLRK HRSGAREVLA
     MTSSIGEAPK TIARRDELVG TLQRYGLLGP DAAMDNILSL KVEDILERRL QTIVYRKGLA
     RSPKQARQLI THGHIAINGQ RVSVPSYMVS IAEEAGIMYY ATSSLGDEAN GERQRIMNQR
     A
//
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