ID A2ST80_METLZ Unreviewed; 418 AA.
AC A2ST80;
DT 06-MAR-2007, integrated into UniProtKB/TrEMBL.
DT 06-MAR-2007, sequence version 1.
DT 27-MAR-2024, entry version 86.
DE RecName: Full=tryptophan--tRNA ligase {ECO:0000256|ARBA:ARBA00013161};
DE EC=6.1.1.2 {ECO:0000256|ARBA:ARBA00013161};
DE AltName: Full=Tryptophanyl-tRNA synthetase {ECO:0000256|ARBA:ARBA00030268};
GN OrderedLocusNames=Mlab_1369 {ECO:0000313|EMBL:ABN07536.1};
OS Methanocorpusculum labreanum (strain ATCC 43576 / DSM 4855 / Z).
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanomicrobiales; Methanocorpusculaceae; Methanocorpusculum.
OX NCBI_TaxID=410358 {ECO:0000313|EMBL:ABN07536.1, ECO:0000313|Proteomes:UP000000365};
RN [1] {ECO:0000313|EMBL:ABN07536.1, ECO:0000313|Proteomes:UP000000365}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43576 / DSM 4855 / Z {ECO:0000313|Proteomes:UP000000365};
RX PubMed=21304657; DOI=10.4056.sigs.35575;
RA Anderson I.J., Sieprawska-Lupa M., Goltsman E., Lapidus A., Copeland A.,
RA Glavina Del Rio T., Tice H., Dalin E., Barry K., Pitluck S., Hauser L.,
RA Land M., Lucas S., Richardson P., Whitman W.B., Kyrpides N.C.;
RT "Complete genome sequence of Methanocorpusculum labreanum type strain Z.";
RL Stand. Genomic Sci. 1:197-203(2009).
CC -!- SIMILARITY: Belongs to the class-I aminoacyl-tRNA synthetase family.
CC {ECO:0000256|ARBA:ARBA00005594, ECO:0000256|RuleBase:RU363036}.
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DR EMBL; CP000559; ABN07536.1; -; Genomic_DNA.
DR RefSeq; WP_011833739.1; NC_008942.1.
DR AlphaFoldDB; A2ST80; -.
DR STRING; 410358.Mlab_1369; -.
DR GeneID; 4795217; -.
DR KEGG; mla:Mlab_1369; -.
DR eggNOG; arCOG01887; Archaea.
DR HOGENOM; CLU_032621_3_0_2; -.
DR OrthoDB; 371821at2157; -.
DR Proteomes; UP000000365; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004830; F:tryptophan-tRNA ligase activity; IEA:UniProtKB-EC.
DR GO; GO:0006436; P:tryptophanyl-tRNA aminoacylation; IEA:InterPro.
DR Gene3D; 3.40.50.620; HUPs; 1.
DR Gene3D; 1.10.240.10; Tyrosyl-Transfer RNA Synthetase; 1.
DR InterPro; IPR002305; aa-tRNA-synth_Ic.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR InterPro; IPR002306; Trp-tRNA-ligase.
DR PANTHER; PTHR10055:SF1; TRYPTOPHAN--TRNA LIGASE, CYTOPLASMIC; 1.
DR PANTHER; PTHR10055; TRYPTOPHANYL-TRNA SYNTHETASE; 1.
DR Pfam; PF00579; tRNA-synt_1b; 2.
DR PRINTS; PR01039; TRNASYNTHTRP.
DR SUPFAM; SSF52374; Nucleotidylyl transferase; 1.
PE 3: Inferred from homology;
KW Aminoacyl-tRNA synthetase {ECO:0000256|ARBA:ARBA00023146,
KW ECO:0000256|RuleBase:RU363036};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU363036};
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000256|RuleBase:RU363036};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU363036};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917,
KW ECO:0000256|RuleBase:RU363036};
KW Reference proteome {ECO:0000313|Proteomes:UP000000365}.
SQ SEQUENCE 418 AA; 46939 MW; 0A15562EFE9C18C5 CRC64;
MAEQINPWSS TPKVDINRLF EEFGIESFAA QKQLLEDQPV FIRRDIVAGH RGYEAISEAI
RMKKPFHVLT GFMPSGHPHF GHLMVMKEVV WHINQGGRGF ISMADREAHA VRGLSWDVCD
TYAREYMECL YALGFKGEIY SQRKNNPLKD LAFEAATKIN FSELSAIYGF GPETELAHAM
SVAMQVGDIL YPQLVGGAAP TIVPVGIDQD PHIRLTRDVT KALRMFLVED RGSHISIRVK
KATPEAIDAV AKRFKGAKKY EGHIDLPAGY TVAAVDEIVR SVEQEFGGFG FMLPSSTYHS
FLQGLQGGKM SSSVPESLVW FDDTENDAKK KIMGALTGGR QTLEEQKQLG GEPEKCSIYQ
LNKFHMQEDD KELAKMCEAC KAGELMCGTC KKETLERVLT FLKEFKEKRD EVSHMVEW
//
