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Database: UniProt
Entry: A2XZL0
LinkDB: A2XZL0
Original site: A2XZL0 
ID   MT2C_ORYSI              Reviewed;          84 AA.
AC   A2XZL0; A5JVN2; P93433; Q0DLB2; Q65XV5;
DT   24-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT   20-MAR-2007, sequence version 1.
DT   16-JAN-2019, entry version 46.
DE   RecName: Full=Metallothionein-like protein 2C;
DE   AltName: Full=Class I metallothionein-like protein 2C;
DE   AltName: Full=OsMT-I-2c;
DE   AltName: Full=OsMT2b;
GN   Name=MT2C; Synonyms=MT2BL; ORFNames=OsI_017503;
OS   Oryza sativa subsp. indica (Rice).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliophyta; Liliopsida; Poales; Poaceae; BOP clade;
OC   Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX   NCBI_TaxID=39946;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=cv. Milyang 23;
RA   Lee M.C., Park J.Y., Lee J.S., Eun M.Y.;
RT   "Molecular cloning and characterization of a metallothionein-like
RT   protein gene in rice.";
RL   Submitted (DEC-1996) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=cv. Jiayu 948;
RX   PubMed=18258694; DOI=10.1104/pp.107.110304;
RA   Yuan J., Chen D., Ren Y., Zhang X., Zhao J.;
RT   "Characteristic and expression analysis of a metallothionein gene,
RT   OsMT2b, down-regulated by cytokinin suggests functions in root
RT   development and seed embryo germination of rice.";
RL   Plant Physiol. 146:1637-1650(2008).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. 93-11;
RX   PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA   Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA   Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H.,
RA   Cong L., Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J.,
RA   Wang J., Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X.,
RA   Wang J., Wang X., Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y.,
RA   Zhang Z., Bao J., Han Y., Dong L., Ji J., Chen P., Wu S., Liu J.,
RA   Xiao Y., Bu D., Tan J., Yang L., Ye C., Zhang J., Xu J., Zhou Y.,
RA   Yu Y., Zhang B., Zhuang S., Wei H., Liu B., Lei M., Yu H., Li Y.,
RA   Xu H., Wei S., He X., Fang L., Zhang Z., Zhang Y., Huang X., Su Z.,
RA   Tong W., Li J., Tong Z., Li S., Ye J., Wang L., Fang L., Lei T.,
RA   Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F., Xu H.,
RA   Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q., Li W.,
RA   Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J., Gao L.,
RA   Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M., McDermott J.,
RA   Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT   "The genomes of Oryza sativa: a history of duplications.";
RL   PLoS Biol. 3:266-281(2005).
RN   [4]
RP   GENE FAMILY.
RX   PubMed=17002881; DOI=10.5483/BMBRep.2006.39.5.595;
RA   Zhou G., Xu Y., Li J., Yang L., Liu J.-Y.;
RT   "Molecular analyses of the metallothionein gene family in rice (Oryza
RT   sativa L.).";
RL   J. Biochem. Mol. Biol. 39:595-606(2006).
CC   -!- FUNCTION: Metallothioneins have a high content of cysteine
CC       residues that bind various heavy metals. Acts as reactive oxygen
CC       species (ROS) scavenger in the cytosol. Possesses superoxide anion
CC       and hydroxyl radical scavenging activities in vitro. Plays a role
CC       during root development, lateral root initiation and seed embryo
CC       germination, possibly by regulating levels of cytokinin.
CC       {ECO:0000250|UniProtKB:A3AZ88}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC       {ECO:0000250|UniProtKB:A3AZ88}.
CC   -!- SIMILARITY: Belongs to the metallothionein superfamily. Type 15
CC       family. {ECO:0000305}.
DR   EMBL; U77294; AAB18814.1; -; mRNA.
DR   EMBL; Y08529; CAA69845.1; -; mRNA.
DR   EMBL; EF584509; ABQ57494.1; -; mRNA.
DR   EMBL; CM000130; EAY96270.1; -; Genomic_DNA.
DR   PIR; T03787; T03787.
DR   ProteinModelPortal; A2XZL0; -.
DR   PRIDE; A2XZL0; -.
DR   EnsemblPlants; BGIOSGA019039-TA; BGIOSGA019039-PA; BGIOSGA019039.
DR   Gramene; BGIOSGA019039-TA; BGIOSGA019039-PA; BGIOSGA019039.
DR   OMA; MVIAEAT; -.
DR   Proteomes; UP000007015; Chromosome 5.
DR   GO; GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0072593; P:reactive oxygen species metabolic process; IEA:EnsemblPlants.
DR   InterPro; IPR000347; Metalthion_15p.
DR   PANTHER; PTHR33543; PTHR33543; 1.
DR   Pfam; PF01439; Metallothio_2; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Cytoplasm; Metal-binding; Metal-thiolate cluster;
KW   Reference proteome; Stress response.
FT   CHAIN         1     84       Metallothionein-like protein 2C.
FT                                /FTId=PRO_0000296354.
FT   CONFLICT     21     21       G -> S (in Ref. 2; ABQ57494).
FT                                {ECO:0000305}.
SQ   SEQUENCE   84 AA;  7969 MW;  5BF71575A9142311 CRC64;
     MSCCGGNCGC GSGCQCGGGC GGCKMFPDVE ATATTKTFVL AAPSNKASSG GMEMAVESGE
     NGGCGCNTCK CGTSCSGCSC CSCN
//
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