ID SPXM3_ORYSI Reviewed; 698 AA.
AC A2Y8U6;
DT 05-OCT-2010, integrated into UniProtKB/Swiss-Prot.
DT 20-MAR-2007, sequence version 1.
DT 27-MAR-2024, entry version 73.
DE RecName: Full=SPX domain-containing membrane protein OsI_21475;
GN ORFNames=OsI_21475;
OS Oryza sativa subsp. indica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39946;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. 93-11;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily.
CC {ECO:0000305}.
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DR EMBL; CM000131; EAY99506.1; -; Genomic_DNA.
DR AlphaFoldDB; A2Y8U6; -.
DR STRING; 39946.A2Y8U6; -.
DR iPTMnet; A2Y8U6; -.
DR EnsemblPlants; BGIOSGA022231-TA; BGIOSGA022231-PA; BGIOSGA022231.
DR Gramene; BGIOSGA022231-TA; BGIOSGA022231-PA; BGIOSGA022231.
DR HOGENOM; CLU_025236_1_0_1; -.
DR OMA; MMLVYSY; -.
DR Proteomes; UP000007015; Chromosome 6.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR CDD; cd14479; SPX-MFS_plant; 1.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR004331; SPX_dom.
DR InterPro; IPR045264; SPXM_SPX_plant.
DR PANTHER; PTHR23510; INNER MEMBRANE TRANSPORT PROTEIN YAJR; 1.
DR PANTHER; PTHR23510:SF78; SPX DOMAIN-CONTAINING MEMBRANE PROTEIN OS06G0129400; 1.
DR Pfam; PF07690; MFS_1; 1.
DR Pfam; PF03105; SPX; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS51382; SPX; 1.
PE 3: Inferred from homology;
KW Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT CHAIN 1..698
FT /note="SPX domain-containing membrane protein OsI_21475"
FT /id="PRO_0000398574"
FT TRANSMEM 248..268
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 279..299
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 316..336
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 339..357
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 376..396
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 412..432
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 514..534
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 545..565
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 577..597
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 605..625
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 671..691
FT /note="Helical"
FT /evidence="ECO:0000255"
FT DOMAIN 2..145
FT /note="SPX"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00714"
FT REGION 467..495
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 698 AA; 77650 MW; FF082AB186330B32 CRC64;
MVNFGKKLMA DQIPEWKGYY INYKLMKKKV KQYGQQVQQG EKDRRRVLKD FSKMLDDQIE
KIVLFLLEQQ GALASRIEKL GKQRAILAEQ PDISAIAELR EAYREVGLDL IKLLKFVDLN
ATGIRKILKK FDKRFGYRFT DYYVTSRSNH PYSQLQQVFK HVGVGAVVGA LSRNLADLQE
RQGSYLSIYD QPSTALKDPI IDMINSSVDK LTRSTNFLRF LGQHALIVGE ESPSTAEEEE
IEDQKYHFMS LMLNLVNTFL YMVNTYIIVP TADDYSVSLG AASTVCGVVI GSMAVAQIFS
SVYFSAWSNK SYFRPLIFSS IVLFLGNVCY AMAYDMKSLT VLIIGRLLCG MGSARAVNRR
YISDCVPARI RMQASAGFVS ASALGMACGP ALAGLLQWKF KIYMVTFNQS TLPGWVMAVA
WLLYLVWLWI SFKEPNRATE VNGTQQNPAS VQRADIEQLE NGLAQPLLRD SSKKDEDDDE
EVDDSEEGTH DSRKPATSIG SAYRLLTPSV KVQLLIYFML KYAMEILLSE SSVITNHYFN
WNTSAVAIFL AILGLTVLPV NAVVGTYISN MFEDRQLLMV SQITLLVGII FSFKITSTYS
VVQYVVSALV TFVSAEVLEG VNLSLLSSVM SSRLSRGTYN GGLLSTEAGT LARVVADCTI
TAAGYLGIGK LLNVTLLPSL VICAASIAST FLTYNSLF
//
