ID A3CL58_STRSV Unreviewed; 232 AA.
AC A3CL58;
DT 20-MAR-2007, integrated into UniProtKB/TrEMBL.
DT 20-MAR-2007, sequence version 1.
DT 24-JAN-2024, entry version 77.
DE SubName: Full=Precorrin-8X methylmutase / precorrin isomerase, putative {ECO:0000313|EMBL:ABN43913.1};
DE EC=5.4.1.2 {ECO:0000313|EMBL:ABN43913.1};
GN OrderedLocusNames=SSA_0465 {ECO:0000313|EMBL:ABN43913.1};
OS Streptococcus sanguinis (strain SK36).
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=388919 {ECO:0000313|EMBL:ABN43913.1, ECO:0000313|Proteomes:UP000002148};
RN [1] {ECO:0000313|EMBL:ABN43913.1, ECO:0000313|Proteomes:UP000002148}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SK36 {ECO:0000313|EMBL:ABN43913.1,
RC ECO:0000313|Proteomes:UP000002148};
RX PubMed=17277061; DOI=10.1128/JB.01808-06;
RA Xu P., Alves J.M., Kitten T., Brown A., Chen Z., Ozaki L.S., Manque P.,
RA Ge X., Serrano M.G., Puiu D., Hendricks S., Wang Y., Chaplin M.D., Akan D.,
RA Paik S., Peterson D.L., Macrina F.L., Buck G.A.;
RT "Genome of the opportunistic pathogen Streptococcus sanguinis.";
RL J. Bacteriol. 189:3166-3175(2007).
CC -!- PATHWAY: Cofactor biosynthesis; adenosylcobalamin biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004953}.
CC -!- SIMILARITY: Belongs to the CobH/CbiC family.
CC {ECO:0000256|ARBA:ARBA00009774}.
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DR EMBL; CP000387; ABN43913.1; -; Genomic_DNA.
DR RefSeq; WP_002910554.1; NC_009009.1.
DR RefSeq; YP_001034463.1; NC_009009.1.
DR AlphaFoldDB; A3CL58; -.
DR STRING; 388919.SSA_0465; -.
DR KEGG; ssa:SSA_0465; -.
DR PATRIC; fig|388919.9.peg.449; -.
DR eggNOG; COG2082; Bacteria.
DR HOGENOM; CLU_084703_1_1_9; -.
DR OrthoDB; 9780708at2; -.
DR UniPathway; UPA00148; -.
DR Proteomes; UP000002148; Chromosome.
DR GO; GO:0016993; F:precorrin-8X methylmutase activity; IEA:InterPro.
DR GO; GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.40.50.10230; Cobalamin biosynthesis CobH/CbiC, precorrin-8X methylmutase; 1.
DR InterPro; IPR003722; Cbl_synth_CobH/CbiC.
DR InterPro; IPR036588; CobH/CbiC_sf.
DR PANTHER; PTHR43588; COBALT-PRECORRIN-8 METHYLMUTASE; 1.
DR PANTHER; PTHR43588:SF1; COBALT-PRECORRIN-8 METHYLMUTASE; 1.
DR Pfam; PF02570; CbiC; 1.
DR SUPFAM; SSF63965; Precorrin-8X methylmutase CbiC/CobH; 1.
PE 3: Inferred from homology;
KW Cobalamin biosynthesis {ECO:0000256|ARBA:ARBA00022573};
KW Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000313|EMBL:ABN43913.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000002148}.
FT DOMAIN 10..208
FT /note="Cobalamin biosynthesis precorrin-8X methylmutase
FT CobH/CbiC"
FT /evidence="ECO:0000259|Pfam:PF02570"
SQ SEQUENCE 232 AA; 25601 MW; 126B3F30BC3224CE CRC64;
MTYIQNPSSI EEKSFQIIQS MITEKDPDYV FHSEMEESII KRAIHTTGDF DYLYTMRFEH
DVLKKIEEVI RAKGTILLDS NISLNGINKR VLDQLGVSYR CLISDEEVVA LAKEKQITRA
MAAVEIAAKI EGPKVFAFGG APTALSYLIE LAEQGLVEAD AVIGVPVGFI NVEESKEELL
QSGLPALVNL GRKGGSTIVV AIVNAIIYQL REVVTDDYVR YSTPSSKEGG KN
//
