ID A3CQW0_STRSV Unreviewed; 154 AA.
AC A3CQW0;
DT 20-MAR-2007, integrated into UniProtKB/TrEMBL.
DT 20-MAR-2007, sequence version 1.
DT 27-MAR-2024, entry version 78.
DE RecName: Full=Transcriptional regulator CtsR {ECO:0000256|ARBA:ARBA00014129, ECO:0000256|PIRNR:PIRNR010607};
GN Name=ctsR {ECO:0000313|EMBL:ABN45565.1};
GN OrderedLocusNames=SSA_2200 {ECO:0000313|EMBL:ABN45565.1};
OS Streptococcus sanguinis (strain SK36).
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=388919 {ECO:0000313|EMBL:ABN45565.1, ECO:0000313|Proteomes:UP000002148};
RN [1] {ECO:0000313|EMBL:ABN45565.1, ECO:0000313|Proteomes:UP000002148}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SK36 {ECO:0000313|EMBL:ABN45565.1,
RC ECO:0000313|Proteomes:UP000002148};
RX PubMed=17277061; DOI=10.1128/JB.01808-06;
RA Xu P., Alves J.M., Kitten T., Brown A., Chen Z., Ozaki L.S., Manque P.,
RA Ge X., Serrano M.G., Puiu D., Hendricks S., Wang Y., Chaplin M.D., Akan D.,
RA Paik S., Peterson D.L., Macrina F.L., Buck G.A.;
RT "Genome of the opportunistic pathogen Streptococcus sanguinis.";
RL J. Bacteriol. 189:3166-3175(2007).
CC -!- SIMILARITY: Belongs to the CtsR family. {ECO:0000256|ARBA:ARBA00010189,
CC ECO:0000256|PIRNR:PIRNR010607}.
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DR EMBL; CP000387; ABN45565.1; -; Genomic_DNA.
DR RefSeq; WP_002899234.1; NC_009009.1.
DR RefSeq; YP_001036115.1; NC_009009.1.
DR AlphaFoldDB; A3CQW0; -.
DR STRING; 388919.SSA_2200; -.
DR GeneID; 61535526; -.
DR KEGG; ssa:SSA_2200; -.
DR PATRIC; fig|388919.9.peg.2085; -.
DR eggNOG; COG4463; Bacteria.
DR HOGENOM; CLU_118139_0_0_9; -.
DR OrthoDB; 1680813at2; -.
DR Proteomes; UP000002148; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:UniProtKB-UniRule.
DR Gene3D; 1.10.1200.150; Transcriptional regulator CtsR, C-terminal domain; 1.
DR Gene3D; 3.30.56.130; Transcriptional regulator CtsR, winged HTH domain; 1.
DR InterPro; IPR008463; CtsR.
DR InterPro; IPR041473; CtsR_C.
DR InterPro; IPR041908; CtsR_C_sf.
DR InterPro; IPR040465; CtsR_N.
DR InterPro; IPR041902; CtsR_N_sf.
DR Pfam; PF05848; CtsR; 1.
DR Pfam; PF17727; CtsR_C; 1.
DR PIRSF; PIRSF010607; Txn_repr_CtsR; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PIRNR:PIRNR010607};
KW Reference proteome {ECO:0000313|Proteomes:UP000002148};
KW Repressor {ECO:0000256|ARBA:ARBA00022491, ECO:0000256|PIRNR:PIRNR010607};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|PIRNR:PIRNR010607};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW ECO:0000256|PIRNR:PIRNR010607}.
FT DOMAIN 5..73
FT /note="CtsR N-terminal HTH"
FT /evidence="ECO:0000259|Pfam:PF05848"
FT DOMAIN 78..145
FT /note="CtsR C-terminal dimerization"
FT /evidence="ECO:0000259|Pfam:PF17727"
SQ SEQUENCE 154 AA; 17151 MW; BAACA1307643AD56 CRC64;
MGAKNTSDSI EAYIKSILAQ AGMVELKRSE LADVFQVVPS QINYVIKTRF TESRGYIVES
KRGGGGYIRI GKIEFSDRHQ MLCGLYDSVG ERVSQQVFTD VIQLLFDEKI MTEREGNLIL
STASDSILGD GAAVIRARIL KKILQQLDRK GMES
//